7ZLY

Crystal structure of human GPCR Niacin receptor (HCA2) expressed from Spodoptera frugiperda

Summary for 7ZLY

Entry DOI	10.2210/pdb7zly/pdb
Descriptor	Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562, OLEIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate (3 entities in total)
Functional Keywords	niacin receptor, hydroxycarboxylic acid receptor 2, hca2, gpcr, membrane protein structure, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	1
Total formula weight	51868.83
Authors	Yang, Y.,Kang, H.J.,Gao, R.G.,Wang, J.J.,FiBerto, J.F.,Wu, L.J.,Tong, J.H.,Han, G.W.,Qu, L.,Wu, Y.R.,Pileski, R.,Li, X.M.,Zhang, X.C.,Zhao, S.W.,Kenakin, T.,Wang, Q.,Stevens, R.C.,Peng, W.,Roth, B.L.,Rao, Z.H.,Liu, Z.J. (deposition date: 2022-04-17, release date: 2023-04-12, Last modification date: 2024-02-07)
Primary citation	Yang, Y.,Kang, H.J.,Gao, R.,Wang, J.,Han, G.W.,DiBerto, J.F.,Wu, L.,Tong, J.,Qu, L.,Wu, Y.,Pileski, R.,Li, X.,Zhang, X.C.,Zhao, S.,Kenakin, T.,Wang, Q.,Stevens, R.C.,Peng, W.,Roth, B.L.,Rao, Z.,Liu, Z.J. Structural insights into the human niacin receptor HCA2-G i signalling complex. Nat Commun, 14:1692-1692, 2023 Cited by PubMed: 36973264 DOI: 10.1038/s41467-023-37177-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation