7ZLY

Crystal structure of human GPCR Niacin receptor (HCA2) expressed from Spodoptera frugiperda

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562	polymer	431	49817.5	1	UniProt (Q8TDS4) UniProt (P0ABE7) Pfam (PF00001) Pfam (PF07361)	Homo sapiens (human)	G-protein coupled receptor 109A,G-protein coupled receptor HM74A,Niacin receptor 1,Nicotinic acid receptor,Cytochrome b-562
2	B, C, D, E, F... (A)	OLEIC ACID	non-polymer		282.5	6	Chemie (OLA)
3	H (A)	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate	non-polymer		356.5	1	Chemie (OLC)

Sequence modifications

A: 1 - 219 (UniProt: Q8TDS4)

PDB	External Database	Details
Val 70	Ala 70	conflict

A: 220 - 324 (UniProt: P0ABE7)

PDB	External Database	Details
Trp 226	Met 29	conflict
Ile 321	His 124	conflict
Leu 325	-	linker

A: 326 - 431 (UniProt: Q8TDS4)

PDB	External Database	Details
Val 393	Ser 287	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	49817.5
Non-Polymers*	Number of molecules	7
	Total formula weight	2051.3
All*	Total formula weight	51868.8

*Water molecules are not included.