8IP4
| Cryo-EM structure of hMRS-highEDTA | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Magnesium transporter MRS2 homolog, ... | 著者 | Li, M, Li, Y, Yang, X, Shen, Y.Q. | 登録日 | 2023-03-14 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel. Nat Commun, 14, 2023
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8IP5
| Cryo-EM structure of hMRS2-lowEDTA | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Magnesium transporter MRS2 homolog, ... | 著者 | Li, M, Li, Y, Yang, X, Shen, Y.Q. | 登録日 | 2023-03-14 | 公開日 | 2023-06-14 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel. Nat Commun, 14, 2023
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6LAE
| Crystal structure of the DNA-binding domain of human XPA in complex with DNA | 分子名称: | DNA (5'-D(P*GP*CP*AP*TP*CP*TP*CP*GP*CP*CP*T)-3'), DNA (5'-D(P*TP*GP*GP*CP*GP*AP*GP*AP*TP*GP*C)-3'), DNA repair protein complementing XP-A cells, ... | 著者 | Lian, F.M, Yang, X, Jiang, Y.L, Yang, F, Li, C, Yang, W, Qian, C. | 登録日 | 2019-11-12 | 公開日 | 2020-02-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | New structural insights into the recognition of undamaged splayed-arm DNA with a single pair of non-complementary nucleotides by human nucleotide excision repair protein XPA. Int.J.Biol.Macromol., 148, 2020
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6LYG
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7F6V
| Cryo-EM structure of the human TACAN channel in a closed state | 分子名称: | CHOLESTEROL, Ion channel TACAN | 著者 | Chen, X.Z, Wang, Y.J, Li, Y, Yang, X, Shen, Y.Q. | 登録日 | 2021-06-25 | 公開日 | 2022-02-16 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Cryo-EM structure of the human TACAN in a closed state. Cell Rep, 38, 2022
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7XGL
| Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in Apo form | 分子名称: | CHLORIDE ION, GLYCEROL, Quinolinate Phosphoribosyl Transferase, ... | 著者 | Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z. | 登録日 | 2022-04-05 | 公開日 | 2023-03-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. Acs Chem.Biol., 18, 2023
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7XGM
| Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in complex with Quinolinic Acid (QA) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, QUINOLINIC ACID, ... | 著者 | Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z. | 登録日 | 2022-04-05 | 公開日 | 2023-03-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. Acs Chem.Biol., 18, 2023
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7XGN
| Quinolinate Phosphoribosyl Transferase (QAPRTase) from Streptomyces pyridomyceticus NRRL B-2517 in complex with Nicotinic Acid (NA) | 分子名称: | CHLORIDE ION, NICOTINIC ACID, Quinolinate Phosphoribosyl Transferase, ... | 著者 | Zhou, Z, Yang, X, Huang, T, Wang, X, Liang, R, Zheng, J, Dai, S, Lin, S, Deng, Z. | 登録日 | 2022-04-05 | 公開日 | 2023-03-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. Acs Chem.Biol., 18, 2023
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7WL5
| Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Equine/Guangxi/25/2010(H5N1) and A/Equine/Guangxi/68/2010(H5N1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | 著者 | Wei, X, Yang, X, Chen, Q, Meng, G. | 登録日 | 2022-01-12 | 公開日 | 2023-01-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of an avian influenza H5 hemagglutinin from the influenza virus A/Equine/Guangxi/25/2010(H5N1) and A/Equine/Guangxi/68/2010(H5N1) To Be Published
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7DD7
| Structure of Calcium-Sensing Receptor in complex with Evocalcet | 分子名称: | 2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wen, T.L, Yang, X, Shen, Y.Q. | 登録日 | 2020-10-27 | 公開日 | 2021-06-16 | 最終更新日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for activation and allosteric modulation of full-length calcium-sensing receptor. Sci Adv, 7, 2021
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7DD5
| Structure of Calcium-Sensing Receptor in complex with NPS-2143 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile, ... | 著者 | Wen, T.L, Yang, X, Shen, Y.Q. | 登録日 | 2020-10-27 | 公開日 | 2021-06-16 | 最終更新日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for activation and allosteric modulation of full-length calcium-sensing receptor. Sci Adv, 7, 2021
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7DD6
| Structure of Ca2+/L-Trp-bonnd Calcium-Sensing Receptor in active state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Wen, T.L, Yang, X, Shen, Y.Q. | 登録日 | 2020-10-27 | 公開日 | 2021-06-16 | 最終更新日 | 2021-06-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for activation and allosteric modulation of full-length calcium-sensing receptor. Sci Adv, 7, 2021
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7DSC
| CALHM1 open state with disordered CTH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1 | 著者 | Ren, Y, Yang, X, Shen, Y.Q. | 登録日 | 2020-12-30 | 公開日 | 2022-01-05 | 最終更新日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel. J.Biol.Chem., 298, 2022
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7DSD
| CALHM1 close state with disordered CTH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1 | 著者 | Ren, Y, Yang, X, Shen, Y.Q. | 登録日 | 2020-12-30 | 公開日 | 2022-01-05 | 最終更新日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel. J.Biol.Chem., 298, 2022
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7DSE
| CALHM1 close state with ordered CTH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcium homeostasis modulator 1 | 著者 | Ren, Y, Yang, X, Shen, Y.Q. | 登録日 | 2020-12-30 | 公開日 | 2022-01-05 | 最終更新日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of the heptameric calcium homeostasis modulator 1 channel. J.Biol.Chem., 298, 2022
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7Y37
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5Z9Y
| Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP | 分子名称: | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Thiazole synthase | 著者 | Zhang, J, Zhang, B, Zhao, Y, Yang, X, Huang, M, Cui, P, Zhang, W, Li, J, Zhang, Y. | 登録日 | 2018-02-05 | 公開日 | 2018-04-11 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG). Biochem. Biophys. Res. Commun., 497, 2018
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7Y6I
| Cryo-EM structure of human sodium-chloride cotransporter | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Nan, J, Yang, X, Shan, Z, Yuan, Y, Zhang, Y.Q. | 登録日 | 2022-06-20 | 公開日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Cryo-EM structure of the human sodium-chloride cotransporter NCC. Sci Adv, 8, 2022
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6BJ8
| TCR55 in complex with Pep20/HLA-B35 | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | 著者 | Jude, K.M, Sibener, L.V, Yang, X, Garcia, K.C. | 登録日 | 2017-11-05 | 公開日 | 2018-07-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding. Cell, 174, 2018
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7EHL
| Cryo-EM structure of human ABCB8 transporter in nucleotide binding state | 分子名称: | CHOLESTEROL, MAGNESIUM ION, Mitochondrial potassium channel ATP-binding subunit, ... | 著者 | Li, S.J, Yang, X, Shen, Y.Q. | 登録日 | 2021-03-29 | 公開日 | 2021-05-05 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Cryo-EM structure of human ABCB8 transporter in nucleotide binding state. Biochem.Biophys.Res.Commun., 557, 2021
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8HNC
| Cryo-EM structure of human OATP1B1 in complex with bilirubin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ... | 著者 | Shan, Z, Yang, X, Liu, H, Nan, J, Yuan, Y, Zhang, Y. | 登録日 | 2022-12-07 | 公開日 | 2023-09-13 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | Cryo-EM structures of human organic anion transporting polypeptide OATP1B1. Cell Res., 33, 2023
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8HND
| Cryo-EM structure of human OATP1B1 in complex with estrone-3-sulfate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier organic anion transporter family member 1B1, ... | 著者 | Shan, Z, Yang, X, Liu, H, Nan, J, Yuan, Y, Zhang, Y. | 登録日 | 2022-12-07 | 公開日 | 2023-09-13 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Cryo-EM structures of human organic anion transporting polypeptide OATP1B1. Cell Res., 33, 2023
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8HNB
| Cryo-EM structure of human OATP1B1 in apo state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier organic anion transporter family member 1B1 | 著者 | Shan, Z, Yang, X, Zhang, Y. | 登録日 | 2022-12-07 | 公開日 | 2023-09-13 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Cryo-EM structures of human organic anion transporting polypeptide OATP1B1. Cell Res., 33, 2023
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8HNH
| Cryo-EM structure of human OATP1B1 in complex with simeprevir | 分子名称: | (2R,3aR,10Z,11aS,12aR,14aR)-N-(cyclopropylsulfonyl)-2-({7-methoxy-8-methyl-2-[4-(1-methylethyl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)-5-methyl-4,14-dioxo-2,3,3a,4,5,6,7,8,9,11a,12,13,14,14a-tetradecahydrocyclopenta[c]cyclopropa[g][1,6]diazacyclotetradecine-12a(1H)-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Shan, Z, Yang, X, Zhang, Y. | 登録日 | 2022-12-07 | 公開日 | 2023-09-13 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | Cryo-EM structures of human organic anion transporting polypeptide OATP1B1. Cell Res., 33, 2023
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7CAF
| Mycobacterium smegmatis LpqY-SugABC complex in the pre-translocation state | 分子名称: | ABC sugar transporter, permease component, ABC transporter, ... | 著者 | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | 登録日 | 2020-06-08 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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