7DD5

Structure of Calcium-Sensing Receptor in complex with NPS-2143

Summary for 7DD5

• Entry DOI: 10.2210/pdb7dd5/pdb
• EMDB information: 30644
• Descriptor: Calcium-Sensing Receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (8 entities in total)
• Functional Keywords: calcium-sensing receptor, casr, nps-2143, membrane protein
• Biological source: Gallus gallus
• Total number of polymer chains: 2
• Total formula weight: 243190.99

Authors

Wen, T.L.,Yang, X.,Shen, Y.Q. (deposition date: 2020-10-27, release date: 2021-06-16, Last modification date: 2021-06-23)

• Primary citation: Wen, T.,Wang, Z.,Chen, X.,Ren, Y.,Lu, X.,Xing, Y.,Lu, J.,Chang, S.,Zhang, X.,Shen, Y.,Yang, X.; Structural basis for activation and allosteric modulation of full-length calcium-sensing receptor.; Sci Adv, 7:-, 2021; PubMed: 34088669; DOI: 10.1126/sciadv.abg1483

Experimental method

ELECTRON MICROSCOPY (3.2 Å)