7DD5
Structure of Calcium-Sensing Receptor in complex with NPS-2143
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Calcium-Sensing Receptor | polymer | 1069 | 119314.2 | 2 | Pfam (PF01094) Pfam (PF07562) Pfam (PF00003) UniProt (by SIFTS) (A0A8I3AZV5) | Gallus gallus | |
| 2 | C, D, E, F (C, D, E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 3 | G, Q (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | H, I, J, P, R... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 5 | K, L, M, T, U... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 6 | N, W (A, B) | TRYPTOPHAN | non-polymer | 204.2 | 2 | Chemie (TRP) | |||
| 7 | O, X (A, B) | 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile | non-polymer | 408.9 | 2 | Chemie (YP1) | |||
| 8 | Y, Z (A, B) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 238628.5 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2864.9 | |
| All* | Total formula weight | 243191.0 |
