3DVN
 
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9HGR
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7AYP
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7TCZ
 | | Human cytomegalovirus protease mutant (C84A, C87A, C138A, C202A) in complex with inhibitor | | 分子名称: | Assemblin, [1-(2-oxopropyl)-4-phenyl-1H-1,2,3-triazol-5-yl]methyl benzylcarbamate | | 著者 | Hulce, K.R, Bohn, M, Ongpipattanakul, C, Jaishankar, P, Renslo, A.R, Craik, C.S. | | 登録日 | 2021-12-29 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine.
Cell Chem Biol, 29, 2022
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3EQ4
 | | Model of tRNA(Leu)-EF-Tu in the ribosomal pre-accommodated state revealed by cryo-EM | | 分子名称: | 30S ribosomal protein S12, 50S ribosomal protein L11, Elongation factor Tu, ... | | 著者 | Frank, J, Li, W, Agirrezabala, X. | | 登録日 | 2008-09-30 | | 公開日 | 2008-12-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (12 Å) | | 主引用文献 | Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM.
Embo J., 27, 2008
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7AX7
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7AY3
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9HXA
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3EP2
 | | Model of Phe-tRNA(Phe) in the ribosomal pre-accommodated state revealed by cryo-EM | | 分子名称: | 30S ribosomal protein S12, 50S ribosomal protein L11, Elongation factor Tu, ... | | 著者 | Frank, J, Li, W, Agirrezabala, X. | | 登録日 | 2008-09-29 | | 公開日 | 2008-12-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM.
Embo J., 27, 2008
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3EQ3
 | | Model of tRNA(Trp)-EF-Tu in the ribosomal pre-accommodated state revealed by cryo-EM | | 分子名称: | 30S ribosomal protein S12, 50S ribosomal protein L11, Elongation factor Tu, ... | | 著者 | Frank, J, Li, W, Agirrezabala, X. | | 登録日 | 2008-09-30 | | 公開日 | 2008-12-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM.
Embo J., 27, 2008
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9J9A
 | | Staphylococcus aureus exfoliative toxin D | | 分子名称: | SULFATE ION, Serine protease, beta-D-glucopyranose | | 著者 | Tonozuka, T. | | 登録日 | 2024-08-22 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of exfoliative toxin D from Staphylococcus aureus.
Biochem.Biophys.Res.Commun., 733, 2024
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6ZCZ
 | | Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in ternary complex with EY6A Fab and a nanobody. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EY6A heavy chain, ... | | 著者 | Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | | 登録日 | 2020-06-12 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Nat.Struct.Mol.Biol., 27, 2020
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9AT9
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9AV4
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9AV5
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9AV8
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7TYV
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7UL7
 | | Lineage I (Pinneo) Lassa virus glycoprotein bound to 18.5C-M30 Fab | | 分子名称: | 18.5C-M30 Fab Heavy Chain, 18.5C-M30 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Buck, T.K, Enriquez, A.S, Hastie, K.M. | | 登録日 | 2022-04-04 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | Neutralizing Antibodies against Lassa Virus Lineage I.
Mbio, 13, 2022
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7UDS
 | | Structure of lineage I (Pinneo) Lassa virus glycoprotein bound to Fab 25.10C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 25.10C Fab Heavy Chain, ... | | 著者 | Buck, T.K, Enriquez, A.E, Hastie, K.M. | | 登録日 | 2022-03-20 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Neutralizing Antibodies against Lassa Virus Lineage I.
Mbio, 13, 2022
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9AUF
 | | Cas9d 20bp R-loop Complex | | 分子名称: | 3' Target Strand, 5' Target Strand, HNH nuclease domain-containing protein, ... | | 著者 | Fregoso Ocampo, R, Taylor, D.W, Bravo, J.P.K. | | 登録日 | 2024-02-29 | | 公開日 | 2025-01-15 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | DNA targeting by compact Cas9d and its resurrected ancestor.
Nat Commun, 16, 2025
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4XUC
 | | Synthesis and evaluation of heterocyclic catechol mimics as inhibitors of catechol-O-methyltransferase (COMT): Structure with Cmpd18 (1-(biphenyl-3-yl)-3-hydroxypyridin-4(1H)-one) | | 分子名称: | 1-(biphenyl-3-yl)-3-hydroxypyridin-4(1H)-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Catechol O-methyltransferase, ... | | 著者 | Allison, T, Wolkenberg, S, Sanders, J.M, Soisson, S.M. | | 登録日 | 2015-01-25 | | 公開日 | 2015-04-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT).
Acs Med.Chem.Lett., 6, 2015
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4XUD
 | | Synthesis and evaluation of heterocyclic catechol mimics as inhibitors of catechol-O-methyltransferase (COMT): Structure with Cmpd32 ([1-(biphenyl-3-yl)-5-hydroxy-4-oxo-1,4-dihydropyridin-3-yl]boronic acid) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Catechol O-methyltransferase, MAGNESIUM ION, ... | | 著者 | Allison, T, Wolkenberg, S, Sanders, J.M, Soisson, S.M. | | 登録日 | 2015-01-25 | | 公開日 | 2015-04-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT).
Acs Med.Chem.Lett., 6, 2015
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4XUE
 | | Synthesis and evaluation of heterocyclic catechol mimics as inhibitors of catechol-O-methyltransferase (COMT): Structure with Cmpd27b | | 分子名称: | 2-(biphenyl-3-yl)-5-hydroxy-3-methylpyrimidin-4(3H)-one, Catechol O-methyltransferase, MAGNESIUM ION, ... | | 著者 | Allison, T, Wolkenberg, S, Sanders, J.M, Soisson, S.M. | | 登録日 | 2015-01-25 | | 公開日 | 2015-04-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT).
Acs Med.Chem.Lett., 6, 2015
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6CEG
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6DXH
 | | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 4-(4-tert-butylphenyl)-4-oxobutanoate | | 分子名称: | 4-(4-tert-butylphenyl)-4-oxobutanoic acid, UNKNOWN ATOM OR ION, Ubiquitin carboxyl-terminal hydrolase 5, ... | | 著者 | Harding, R.J, Mann, M.K, Ravichandran, M, Ferreira de Freitas, R, Franzoni, I, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Schapira, M, Structural Genomics Consortium (SGC) | | 登録日 | 2018-06-28 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain.
J.Med.Chem., 62, 2019
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