9AT9

Crystal structure of Klebsiella pneumoniae FimH lectin domain bound to D-mannose

Summary for 9AT9

Entry DOI	10.2210/pdb9at9/pdb
Descriptor	FimH, alpha-D-mannopyranose (3 entities in total)
Functional Keywords	lectin domain, adhesin, complex, type 1 pilus, cell adhesion
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	17998.89
Authors	Lopatto, E.,Tamadonfar, K.O.,Hultgren, S.J. (deposition date: 2024-02-26, release date: 2024-09-25, Last modification date: 2024-10-16)
Primary citation	Lopatto, E.D.B.,Pinkner, J.S.,Sanick, D.A.,Potter, R.F.,Liu, L.X.,Bazan Villicana, J.,Tamadonfar, K.O.,Ye, Y.,Zimmerman, M.I.,Gualberto, N.C.,Dodson, K.W.,Janetka, J.W.,Hunstad, D.A.,Hultgren, S.J. Conformational ensembles in Klebsiella pneumoniae FimH impact uropathogenesis. Proc.Natl.Acad.Sci.USA, 121:e2409655121-e2409655121, 2024 Cited by PubMed: 39288182 DOI: 10.1073/pnas.2409655121 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.34 Å)

Structure validation