8JGP
 
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8JGO
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7EKI
 | | human alpha 7 nicotinic acetylcholine receptor in apo-form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Liu, S, Zhao, Y, Sun, D, Tian, C. | | 登録日 | 2021-04-05 | | 公開日 | 2021-05-19 | | 最終更新日 | 2021-06-16 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Structural basis of human alpha 7 nicotinic acetylcholine receptor activation.
Cell Res., 31, 2021
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7EKP
 | | human alpha 7 nicotinic acetylcholine receptor bound to EVP-6124 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide, ... | | 著者 | Liu, S, Zhao, Y, Sun, D, Tian, C. | | 登録日 | 2021-04-06 | | 公開日 | 2021-05-19 | | 最終更新日 | 2021-06-16 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structural basis of human alpha 7 nicotinic acetylcholine receptor activation.
Cell Res., 31, 2021
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7EKT
 | | human alpha 7 nicotinic acetylcholine receptor bound to EVP-6124 and PNU-120596 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide, ... | | 著者 | Liu, S, Zhao, Y, Sun, D, Tian, C. | | 登録日 | 2021-04-06 | | 公開日 | 2021-05-19 | | 最終更新日 | 2021-06-16 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Structural basis of human alpha 7 nicotinic acetylcholine receptor activation.
Cell Res., 31, 2021
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7DHP
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8D1T
 | | Crystal structure of human USP30 in complex with a covalent inhibitor 552 and a Fab | | 分子名称: | (1R,2R,4S,7E)-7-[amino(sulfanyl)methylidene]-2-{[(1P)-3-chloro-3'-(1-cyanocyclopropyl)[1,1'-biphenyl]-4-carbonyl]amino}-7-azabicyclo[2.2.1]heptan-7-ium, 1,2-ETHANEDIOL, Ubiquitin carboxyl-terminal hydrolase 30, ... | | 著者 | Song, X, Butler, J, Li, C, Zhang, K, Zhang, D, Hao, Y. | | 登録日 | 2022-05-27 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | TBD
To Be Published
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8D0A
 | | Crystal structure of human USP30 in complex with a covalent inhibitor 829 and a Fab | | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION, mouse anti-huUSP30 Fab heavy chain, ... | | 著者 | Song, X, Butler, J, Li, C, Zhang, K, Zhang, D, Hao, Y. | | 登録日 | 2022-05-25 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | TBD
To Be Published
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6PGN
 | | PagF single mutant with GPP | | 分子名称: | GERANYL DIPHOSPHATE, MAGNESIUM ION, PagF | | 著者 | Nair, S.K, Hao, Y, Estrada, P. | | 登録日 | 2019-06-24 | | 公開日 | 2019-07-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A Single Amino Acid Switch Alters the Isoprene Donor Specificity in
Ribosomally Synthesized and Post-Translationally Modified Peptide
Prenyltransferases
J. Am. Chem. Soc., 140, 2018
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6PGM
 | | PirF geranyltransferase | | 分子名称: | PirF Geranyltransferase | | 著者 | Nair, S.K, Hao, Y, Estrada, P. | | 登録日 | 2019-06-24 | | 公開日 | 2019-07-03 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A Single Amino Acid Switch Alters the Isoprene Donor Specificity in Ribosomally Synthesized and Post-Translationally Modified Peptide Prenyltransferases.
J.Am.Chem.Soc., 140, 2018
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3OFU
 | | Crystal Structure of Cytochrome P450 CYP101C1 | | 分子名称: | (3E)-4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-3-en-2-one, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Zhou, W, Ma, M, Bell, S.G, Yang, W, Hao, Y, Rees, N.H, Bartlam, M, Wong, L.-L, Rao, Z. | | 登録日 | 2010-08-16 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444.
Chembiochem, 12, 2011
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3OFT
 | | Crystal Structure of Cytochrome P450 CYP101C1 | | 分子名称: | (2R,5R)-hexane-2,5-diol, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Zhou, W, Ma, M, Bell, S.G, Yang, W, Hao, Y, Rees, N.H, Bartlam, M, Wong, L.-L, Rao, Z. | | 登録日 | 2010-08-16 | | 公開日 | 2011-07-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444.
Chembiochem, 12, 2011
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4UX5
 | | Structure of DNA complex of PCG2 | | 分子名称: | 5'-D(*CP*AP*AP*TP*GP*AP*CP*GP*CP*GP*TP*AP*AP*GP)-3', 5'-D(*CP*TP*TP*AP*CP*GP*CP*GP*TP*CP*AP*TP*TP*GP)-3', TRANSCRIPTION FACTOR MBP1 | | 著者 | Liu, J, Huang, J, Zhao, Y, Liu, H, Wang, D, Yang, J, Zhao, W, Taylor, I.A, Peng, Y. | | 登録日 | 2014-08-19 | | 公開日 | 2015-01-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of DNA Recognition by Pcg2 Reveals a Novel DNA Binding Mode for Winged Helix-Turn-Helix Domains.
Nucleic Acids Res., 43, 2015
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4UIS
 | | The cryoEM structure of human gamma-Secretase complex | | 分子名称: | GAMMA-SECRETASE, LYSOZYME | | 著者 | Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y. | | 登録日 | 2015-04-03 | | 公開日 | 2015-06-10 | | 最終更新日 | 2017-08-02 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural Basis of Human Gamma-Secretase Assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5VHG
 | | Crystal structure of pentad mutant GAPR-1 | | 分子名称: | Golgi-associated plant pathogenesis-related protein 1, SULFATE ION | | 著者 | Li, Y, Zhao, Y, Su, M, Chakravarthy, S, Colbert, C.L, Levine, B, Sinha, S.C. | | 登録日 | 2017-04-13 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein.
Acta Crystallogr D Struct Biol, 73, 2017
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5VOU
 | | Structure of AMPA receptor-TARP complex | | 分子名称: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | | 著者 | Chen, S, Zhao, Y, Wang, Y.S, Shekhar, M, Tajkhorshid, E, Gouaux, E. | | 登録日 | 2017-05-03 | | 公開日 | 2017-07-12 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | | 主引用文献 | Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
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5VOT
 | | Structure of AMPA receptor-TARP complex | | 分子名称: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | | 著者 | Chen, S, Zhao, Y, Wang, Y.S, Shekhar, M, Tajkhorshid, E, Gouaux, E. | | 登録日 | 2017-05-03 | | 公開日 | 2017-07-12 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
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4OCH
 | | Apo structure of Smr domain of MutS2 from Deinococcus radiodurans | | 分子名称: | Endonuclease MutS2, GLYCEROL | | 著者 | Zhang, H, Zhao, Y, Xu, Q, Hua, Y.J. | | 登録日 | 2014-01-09 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.4001 Å) | | 主引用文献 | Structural and functional studies of MutS2 from Deinococcus radiodurans.
Dna Repair, 21, 2014
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6ZFO
 | | Association of two complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... | | 著者 | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | | 登録日 | 2020-06-17 | | 公開日 | 2020-07-08 | | 最終更新日 | 2021-12-22 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Nat.Struct.Mol.Biol., 27, 2020
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6Z97
 | | Structure of the prefusion SARS-CoV-2 spike glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin | | 著者 | Duyvesteyn, H.M.E, Ren, J, Zhao, Y, Zhou, D, Huo, J, Carrique, L, Malinauskas, T, Ruza, R.R, Shah, P.N.M, Fry, E.E, Owens, R, Stuart, D.I. | | 登録日 | 2020-06-03 | | 公開日 | 2020-07-01 | | 最終更新日 | 2020-09-23 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike.
Cell Host Microbe, 28, 2020
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6ZDH
 | | SARS-CoV-2 Spike glycoprotein in complex with a neutralizing antibody EY6A Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, ... | | 著者 | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | | 登録日 | 2020-06-14 | | 公開日 | 2020-07-01 | | 最終更新日 | 2021-12-22 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Nat.Struct.Mol.Biol., 27, 2020
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6ZDG
 | | Association of three complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... | | 著者 | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | | 登録日 | 2020-06-14 | | 公開日 | 2020-07-29 | | 最終更新日 | 2021-12-22 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Nat.Struct.Mol.Biol., 27, 2020
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6ZER
 | | Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with EY6A Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... | | 著者 | Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | | 登録日 | 2020-06-16 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Nat.Struct.Mol.Biol., 27, 2020
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6ZCZ
 | | Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in ternary complex with EY6A Fab and a nanobody. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EY6A heavy chain, ... | | 著者 | Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | | 登録日 | 2020-06-12 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Nat.Struct.Mol.Biol., 27, 2020
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3HJC
 | | Crystal structure of the carboxy-terminal domain of HSP90 from Leishmania major, LmjF33.0312 | | 分子名称: | Heat shock protein 83-1, SULFATE ION | | 著者 | Wernimont, A.K, Tempel, W, Walker, J, Lin, Y.H, Hutchinson, A, Mackenzie, F, Fairlamb, A, Kozieradzki, I, Cossar, D, Zhao, Y, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Ferguson, M.A.J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2009-05-21 | | 公開日 | 2009-06-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of the middle and carboxy-terminal domain of HSP90 from Leishmania major, LMJF33.0312
To be Published
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