7EKP

human alpha 7 nicotinic acetylcholine receptor bound to EVP-6124

Summary for 7EKP

• Entry DOI: 10.2210/pdb7ekp/pdb
• EMDB information: 31172
• Descriptor: Neuronal acetylcholine receptor subunit alpha-7, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide, ... (5 entities in total)
• Functional Keywords: alpha 7, nicotinic acetylcholine receptor, apo-form, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 5
• Total formula weight: 289291.38

Authors

Liu, S.,Zhao, Y.,Sun, D.,Tian, C. (deposition date: 2021-04-06, release date: 2021-05-19, Last modification date: 2021-06-16)

• Primary citation: Zhao, Y.,Liu, S.,Zhou, Y.,Zhang, M.,Chen, H.,Eric Xu, H.,Sun, D.,Liu, L.,Tian, C.; Structural basis of human alpha 7 nicotinic acetylcholine receptor activation.; Cell Res., 31:713-716, 2021; PubMed: 33958730; DOI: 10.1038/s41422-021-00509-6

Experimental method

ELECTRON MICROSCOPY (2.85 Å)