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7EKP

human alpha 7 nicotinic acetylcholine receptor bound to EVP-6124

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Neuronal acetylcholine receptor subunit alpha-7polymer50256505.25UniProt (P36544)
Pfam (PF02931)
Pfam (PF02932)
Homo sapiens (Human)
2F, G, H, I, J
(F, G, H, I, J)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.45In PDB
GlyTouCan (G42666HT)
3K, N, Q, T, W
(A, B, C, D, E)
7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamidenon-polymer320.85Chemie (I33)
4L, O, R, U, X
(A, B, C, D, E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.25Chemie (NAG)
5M, P, S, V, Y
(A, B, C, D, E)
CHOLESTEROLnon-polymer386.75Chemie (CLR)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight282525.9
BranchedNumber of molecules5
Total formula weight2122.0
Non-Polymers*Number of molecules15
Total formula weight4643.5
All*Total formula weight289291.4
*Water molecules are not included.

227344

PDB entries from 2024-11-13

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