8I4Z
| CalA3 with hydrolysis product | 分子名称: | 11-oxidanylidene-11-(1~{H}-pyrrol-2-yl)undecanoic acid, Beta-ketoacyl-acyl-carrier-protein synthase I | 著者 | Wang, J, Wang, Z. | 登録日 | 2023-01-21 | 公開日 | 2023-02-22 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.97 Å) | 主引用文献 | C-N bond formation by a polyketide synthase. Nat Commun, 14, 2023
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8I4Y
| CalA3 complex structure with amidation product | 分子名称: | 11-oxidanylidene-11-(1~{H}-pyrrol-2-yl)undecanoic acid, 3-HYDROXYANTHRANILIC ACID, Beta-ketoacyl-acyl-carrier-protein synthase I | 著者 | Wang, J, Wang, Z. | 登録日 | 2023-01-21 | 公開日 | 2023-02-22 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | 主引用文献 | C-N bond formation by a polyketide synthase. Nat Commun, 14, 2023
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3JAV
| Structure of full-length IP3R1 channel in the apo-state determined by single particle cryo-EM | 分子名称: | Inositol 1,4,5-trisphosphate receptor type 1 | 著者 | Fan, G, Baker, M.L, Wang, Z, Baker, M.R, Sinyagovskiy, P.A, Chiu, W, Ludtke, S.J, Serysheva, I.I. | 登録日 | 2015-06-30 | 公開日 | 2015-10-07 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Gating machinery of InsP3R channels revealed by electron cryomicroscopy. Nature, 527, 2015
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5XE0
| Crystal structure of EV-D68-3Dpol in complex with GTP | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein | 著者 | Xie, W, Wang, C, Wang, Z, Li, Q, Wang, C. | 登録日 | 2017-03-30 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol J. Virol., 91, 2017
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6UK5
| Structure of SAM bound CalS10, an amino pentose methyltransferase from Micromonospora echinaspora involved in calicheamicin biosynthesis | 分子名称: | ACETATE ION, CalS10, DI(HYDROXYETHYL)ETHER, ... | 著者 | Alvarado, S.K, Miller, M.D, Xu, W, Wang, Z, Van Lanen, S.G, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2019-10-04 | 公開日 | 2020-10-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of SAM bound CalS10, an amino pentose methyltransferase from Micromonospora echinaspora involved in calicheamicin biosynthesis To Be Published
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6U6X
| Human SAMHD1 bound to deoxyribo(C*G*C*C*T)-oligonucleotide | 分子名称: | DNA SC-GS-SC-SC-DT, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION | 著者 | Taylor, A.B, Bhattacharya, A, Wang, Z, Ivanov, D.N. | 登録日 | 2019-08-30 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification. Nat Commun, 12, 2021
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6U6Y
| Human SAMHD1 bound to ribo(CGCCU)-oligonucleotide | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, RNA CGCCU, ... | 著者 | Taylor, A.B, Bhattacharya, A, Wang, Z, Ivanov, D.N. | 登録日 | 2019-08-30 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification. Nat Commun, 12, 2021
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6V3F
| Structure of NPC1-like intracellular cholesterol transporter 1 (NPC1L1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Huang, C.S, Yu, X, Min, X, Wang, Z. | 登録日 | 2019-11-25 | 公開日 | 2020-07-01 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition Sci Adv, 6, 2020
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6UWD
| Crystal structure of Apo AtmM | 分子名称: | ACETATE ION, D-glucose O-methyltransferase, MAGNESIUM ION | 著者 | Alvarado, S.K, Wang, Z, Miller, M.D, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2019-11-05 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structure of Apo AtmM To Be Published
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6URT
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6UV6
| AtmM with bound rebeccamycin analogue | 分子名称: | 12-beta-D-glucopyranosyl-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione, D-glucose O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Alvarado, S.K, Wang, Z, Miller, M.D, Thorson, J.S, Phillips Jr, G.N. | 登録日 | 2019-11-01 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Structure of AtmM Bound with Glycosylated Indolocarbazole To Be Published
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6V3H
| Structure of NPC1-like intracellular cholesterol transporter 1 (NPC1L1) in complex with an ezetimibe analog | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(2S,3R)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-1-(4-{3-[(methylsulfonyl)amino]prop-1-yn-1-yl}phenyl)-4-oxoazetidin-2-yl]phenyl beta-D-glucopyranosiduronic acid, ... | 著者 | Huang, C.S, Yu, X, Min, X, Wang, Z. | 登録日 | 2019-11-25 | 公開日 | 2020-07-01 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition Sci Adv, 6, 2020
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8X5N
| Tetramer Gabija with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, Gabija protein GajB, ... | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-11-17 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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8WY4
| GajA tetramer with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-10-30 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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8X51
| Cryo-EM structure of Gabija GajA in complex with DNA(focused refinement) | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*TP*T)-3'), ... | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-11-16 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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8X5I
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8WY5
| Structure of Gabija GajA in complex with DNA | 分子名称: | CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*T)-3'), ... | 著者 | Li, J, Wang, Z, Wang, L. | 登録日 | 2023-10-30 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system. Nature, 629, 2024
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7EVP
| Cryo-EM structure of the Gp168-beta-clamp complex | 分子名称: | Beta sliding clamp, Sliding clamp inhibitor | 著者 | Liu, B, Li, S, Liu, Y, Chen, H, Hu, Z, Wang, Z, Gou, L, Zhang, L, Ma, B, Wang, H, Matthews, S, Wang, Y, Zhang, K. | 登録日 | 2021-05-21 | 公開日 | 2022-02-16 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Bacteriophage Twort protein Gp168 is a beta-clamp inhibitor by occupying the DNA sliding channel. Nucleic Acids Res., 49, 2021
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6BUI
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6BO4
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6BUG
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6BUH
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6BO5
| TRPV2 ion channel in partially closed state | 分子名称: | Transient receptor potential cation channel subfamily V member 2 | 著者 | Dosey, T.L, Wang, Z. | 登録日 | 2017-11-18 | 公開日 | 2018-12-05 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures of TRPV2 in distinct conformations provide insight into role of the pore turret. Nat.Struct.Mol.Biol., 26, 2019
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7JR7
| Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4 | 分子名称: | ATP-binding cassette sub-family G member 5, ATP-binding cassette sub-family G member 8, Fab 11F4 heavy chain, ... | 著者 | Huang, C.S, Yu, X, Min, X, Wang, Z, Zhang, H. | 登録日 | 2020-08-11 | 公開日 | 2021-04-07 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies Commun Biol, 4, 2021
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7FAP
| Structure of VAR2CSA-CSA 3D7 | 分子名称: | 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-3)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, Erythrocyte membrane protein 1, PfEMP1 | 著者 | Wang, L, Wang, Z. | 登録日 | 2021-07-07 | 公開日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The molecular mechanism of cytoadherence to placental or tumor cells through VAR2CSA from Plasmodium falciparum. Cell Discov, 7, 2021
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