3D1D
| |
1YTY
| Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen | 分子名称: | 5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein | 著者 | Teplova, M, Yuan, Y.R, Ilin, S, Malinina, L, Phan, A.T, Teplov, A, Patel, D.J. | 登録日 | 2005-02-11 | 公開日 | 2006-01-17 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen. Mol.Cell, 21, 2006
|
|
1YTU
| Structural basis for 5'-end-specific recognition of the guide RNA strand by the A. fulgidus PIWI protein | 分子名称: | 5'-R(P*AP*GP*AP*CP*AP*G)-3', 5'-R(P*UP*GP*UP*C)-3', MAGNESIUM ION, ... | 著者 | Ma, J.B, Yuan, Y.R, Meister, G, Pei, Y, Tuschl, T, Patel, D.J. | 登録日 | 2005-02-11 | 公開日 | 2005-04-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature, 434, 2005
|
|
1ZBH
| |
6MUA
| |
6UF1
| Pistol ribozyme transition-state analog vanadate | 分子名称: | MANGANESE (II) ION, RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(GVA)*UP*CP*CP*AP*A)-3'), RNA (50-MER) | 著者 | Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R. | 登録日 | 2019-09-23 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
2ASD
| oxoG-modified Insertion Ternary Complex | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*T*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', 5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', ... | 著者 | Rechkoblit, O, Malinina, L, Cheng, Y, Kuryavyi, V, Broyde, S, Geacintov, N.E, Patel, D.J. | 登録日 | 2005-08-23 | 公開日 | 2006-01-10 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion Plos Biol., 4, 2006
|
|
6NXF
| |
2AU0
| Unmodified preinsertion binary complex | 分子名称: | 5'-D(*CP*TP*AP*AP*CP*G*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', 5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', CALCIUM ION, ... | 著者 | Rechkoblit, O, Malinina, L, Cheng, Y, Kuryavyi, V, Broyde, S, Geacintov, N.E, Patel, D.J. | 登録日 | 2005-08-26 | 公開日 | 2006-01-10 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion Plos Biol., 4, 2006
|
|
1YKQ
| Crystal structure of Diels-Alder ribozyme | 分子名称: | CADMIUM ION, Diels-Alder ribozyme, MAGNESIUM ION | 著者 | Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J. | 登録日 | 2005-01-18 | 公開日 | 2005-02-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat.Struct.Mol.Biol., 12, 2005
|
|
1YKV
| Crystal structure of the Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene | 分子名称: | (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, Diels-Alder ribozyme, MAGNESIUM ION | 著者 | Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J. | 登録日 | 2005-01-18 | 公開日 | 2005-02-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat.Struct.Mol.Biol., 12, 2005
|
|
1YLS
| Crystal structure of selenium-modified Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene | 分子名称: | (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION, RNA Diels-Alder ribozyme | 著者 | Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J. | 登録日 | 2005-01-19 | 公開日 | 2005-02-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat.Struct.Mol.Biol., 12, 2005
|
|
6O6T
| Crystal structure of Csm6 H132A mutant | 分子名称: | Csm6 | 著者 | Jia, N, Patel, D.J. | 登録日 | 2019-03-07 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity. Mol.Cell, 75, 2019
|
|
6O75
| Crystal structure of Csm1-Csm4 cassette in complex with pppApA | 分子名称: | CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, MANGANESE (II) ION, ... | 著者 | Jia, N, Patel, D.J. | 登録日 | 2019-03-07 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path. Mol.Cell, 75, 2019
|
|
6UFJ
| Pistol ribozyme product crystal structure | 分子名称: | MAGNESIUM ION, RNA (5'-R(*UP*CP*CP*AP*G)-3'), RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(23G))-3'), ... | 著者 | Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R. | 登録日 | 2019-09-24 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.645 Å) | 主引用文献 | Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6O71
| |
6O7B
| Crystal structure of Csm1-Csm4 cassette in complex with cA4 | 分子名称: | CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, Cyclic RNA cA4 | 著者 | Jia, N, Patel, D.J. | 登録日 | 2019-03-07 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path. Mol.Cell, 75, 2019
|
|
6OPF
| |
6UEY
| Pistol ribozyme transition-state analog vanadate | 分子名称: | MAGNESIUM ION, RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(GVA)*UP*CP*CP*AP*A)-3'), RNA (50-MER) | 著者 | Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R. | 登録日 | 2019-09-23 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6O47
| human cGAS core domain (K427E/K428E) bound with RU-521 | 分子名称: | (3~{S})-3-[1-[4,5-bis(chloranyl)-1~{H}-benzimidazol-2-yl]-3-methyl-5-oxidanyl-pyrazol-4-yl]-3~{H}-2-benzofuran-1-one, 2-(4,5-dichloro-1H-benzimidazol-2-yl)-5-methyl-4-[(1R)-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-1,2-dihydro-3H-pyrazol-3-one, CITRIC ACID, ... | 著者 | Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J. | 登録日 | 2019-02-28 | 公開日 | 2019-05-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.196 Å) | 主引用文献 | Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6O7I
| |
207D
| SOLUTION STRUCTURE OF MITHRAMYCIN DIMERS BOUND TO PARTIALLY OVERLAPPING SITES ON DNA | 分子名称: | 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYROXY-7-METHYLANTHRACENE, 2,6-dideoxy-3-C-methyl-beta-D-ribo-hexopyranose-(1-3)-2,6-dideoxy-beta-D-galactopyranose-(1-3)-beta-D-Olivopyranose, DNA (5'-D(*TP*AP*GP*CP*TP*AP*GP*CP*TP*A)-3'), ... | 著者 | Sastry, M, Fiala, R, Patel, D.J. | 登録日 | 1995-04-20 | 公開日 | 1995-09-15 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of mithramycin dimers bound to partially overlapping sites on DNA. J.Mol.Biol., 251, 1995
|
|
6O6X
| |
6O6S
| Crystal structure of Apo Csm6 | 分子名称: | Csm6 | 著者 | Jia, N, Patel, D.J. | 登録日 | 2019-03-07 | 公開日 | 2019-07-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity. Mol.Cell, 75, 2019
|
|
6O7H
| |