Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3D1D
DownloadVisualize
BU of 3d1d by Molmil
Hexagonal crystal structure of Tas3 C-terminal alpha motif
分子名称: RNA-induced transcriptional silencing complex protein tas3
著者Li, H, Patel, D.J.
登録日2008-05-05
公開日2009-04-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
1YTY
DownloadVisualize
BU of 1yty by Molmil
Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen
分子名称: 5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein
著者Teplova, M, Yuan, Y.R, Ilin, S, Malinina, L, Phan, A.T, Teplov, A, Patel, D.J.
登録日2005-02-11
公開日2006-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen.
Mol.Cell, 21, 2006
1YTU
DownloadVisualize
BU of 1ytu by Molmil
Structural basis for 5'-end-specific recognition of the guide RNA strand by the A. fulgidus PIWI protein
分子名称: 5'-R(P*AP*GP*AP*CP*AP*G)-3', 5'-R(P*UP*GP*UP*C)-3', MAGNESIUM ION, ...
著者Ma, J.B, Yuan, Y.R, Meister, G, Pei, Y, Tuschl, T, Patel, D.J.
登録日2005-02-11
公開日2005-04-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.
Nature, 434, 2005
1ZBH
DownloadVisualize
BU of 1zbh by Molmil
3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease
分子名称: 3'-5' exonuclease ERI1, 5'-R(*CP*CP*GP*GP*CP*UP*CP*UP*UP*UP*UP*CP*AP*GP*AP*GP*CP*CP*GP*G)-3', ADENOSINE MONOPHOSPHATE, ...
著者Cheng, Y, Patel, D.J.
登録日2005-04-08
公開日2006-09-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA
To be Published
6MUA
DownloadVisualize
BU of 6mua by Molmil
Crystal structure of Csm1-Csm4 subcomplex in the type III-A CRISPR-Csm interference complex
分子名称: Uncharacterized protein Csm1, Uncharacterized protein Csm4
著者Jia, N, Patel, D.J.
登録日2018-10-22
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6UF1
DownloadVisualize
BU of 6uf1 by Molmil
Pistol ribozyme transition-state analog vanadate
分子名称: MANGANESE (II) ION, RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(GVA)*UP*CP*CP*AP*A)-3'), RNA (50-MER)
著者Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R.
登録日2019-09-23
公開日2019-12-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme.
Angew.Chem.Int.Ed.Engl., 59, 2020
2ASD
DownloadVisualize
BU of 2asd by Molmil
oxoG-modified Insertion Ternary Complex
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*T*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', 5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', ...
著者Rechkoblit, O, Malinina, L, Cheng, Y, Kuryavyi, V, Broyde, S, Geacintov, N.E, Patel, D.J.
登録日2005-08-23
公開日2006-01-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
Plos Biol., 4, 2006
6NXF
DownloadVisualize
BU of 6nxf by Molmil
Crystal structure of mouse REC114 PH domain in complex with ANKRD31 C terminus
分子名称: Ankyrin repeat domain 31, Meiotic recombination protein REC114
著者Wang, J, Patel, D.J.
登録日2019-02-08
公開日2019-04-24
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.791 Å)
主引用文献REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks.
Mol.Cell, 74, 2019
2AU0
DownloadVisualize
BU of 2au0 by Molmil
Unmodified preinsertion binary complex
分子名称: 5'-D(*CP*TP*AP*AP*CP*G*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', 5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', CALCIUM ION, ...
著者Rechkoblit, O, Malinina, L, Cheng, Y, Kuryavyi, V, Broyde, S, Geacintov, N.E, Patel, D.J.
登録日2005-08-26
公開日2006-01-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
Plos Biol., 4, 2006
1YKQ
DownloadVisualize
BU of 1ykq by Molmil
Crystal structure of Diels-Alder ribozyme
分子名称: CADMIUM ION, Diels-Alder ribozyme, MAGNESIUM ION
著者Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J.
登録日2005-01-18
公開日2005-02-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YKV
DownloadVisualize
BU of 1ykv by Molmil
Crystal structure of the Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene
分子名称: (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, Diels-Alder ribozyme, MAGNESIUM ION
著者Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J.
登録日2005-01-18
公開日2005-02-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YLS
DownloadVisualize
BU of 1yls by Molmil
Crystal structure of selenium-modified Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene
分子名称: (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION, RNA Diels-Alder ribozyme
著者Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J.
登録日2005-01-19
公開日2005-02-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
6O6T
DownloadVisualize
BU of 6o6t by Molmil
Crystal structure of Csm6 H132A mutant
分子名称: Csm6
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6O75
DownloadVisualize
BU of 6o75 by Molmil
Crystal structure of Csm1-Csm4 cassette in complex with pppApA
分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, MANGANESE (II) ION, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6UFJ
DownloadVisualize
BU of 6ufj by Molmil
Pistol ribozyme product crystal structure
分子名称: MAGNESIUM ION, RNA (5'-R(*UP*CP*CP*AP*G)-3'), RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(23G))-3'), ...
著者Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R.
登録日2019-09-24
公開日2019-12-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.645 Å)
主引用文献Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme.
Angew.Chem.Int.Ed.Engl., 59, 2020
6O71
DownloadVisualize
BU of 6o71 by Molmil
Crystal structure of Csm6 in complex with cdA4 by soaking cdA4 into Csm6
分子名称: Csm6, Cyclic DNA cdA4
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6O7B
DownloadVisualize
BU of 6o7b by Molmil
Crystal structure of Csm1-Csm4 cassette in complex with cA4
分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, Cyclic RNA cA4
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6OPF
DownloadVisualize
BU of 6opf by Molmil
Crystal structure of dmNxf2 UBA domain fused with Panoramix helix
分子名称: Nuclear RNA export factor 2, Panoramix fusion
著者Wang, J, Patel, D.J.
登録日2019-04-24
公開日2019-07-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.
Nat.Struct.Mol.Biol., 26, 2019
6UEY
DownloadVisualize
BU of 6uey by Molmil
Pistol ribozyme transition-state analog vanadate
分子名称: MAGNESIUM ION, RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(GVA)*UP*CP*CP*AP*A)-3'), RNA (50-MER)
著者Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R.
登録日2019-09-23
公開日2019-12-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme.
Angew.Chem.Int.Ed.Engl., 59, 2020
6O47
DownloadVisualize
BU of 6o47 by Molmil
human cGAS core domain (K427E/K428E) bound with RU-521
分子名称: (3~{S})-3-[1-[4,5-bis(chloranyl)-1~{H}-benzimidazol-2-yl]-3-methyl-5-oxidanyl-pyrazol-4-yl]-3~{H}-2-benzofuran-1-one, 2-(4,5-dichloro-1H-benzimidazol-2-yl)-5-methyl-4-[(1R)-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-1,2-dihydro-3H-pyrazol-3-one, CITRIC ACID, ...
著者Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J.
登録日2019-02-28
公開日2019-05-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.196 Å)
主引用文献Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
6O7I
DownloadVisualize
BU of 6o7i by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system
分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm2, Csm3, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
207D
DownloadVisualize
BU of 207d by Molmil
SOLUTION STRUCTURE OF MITHRAMYCIN DIMERS BOUND TO PARTIALLY OVERLAPPING SITES ON DNA
分子名称: 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYROXY-7-METHYLANTHRACENE, 2,6-dideoxy-3-C-methyl-beta-D-ribo-hexopyranose-(1-3)-2,6-dideoxy-beta-D-galactopyranose-(1-3)-beta-D-Olivopyranose, DNA (5'-D(*TP*AP*GP*CP*TP*AP*GP*CP*TP*A)-3'), ...
著者Sastry, M, Fiala, R, Patel, D.J.
登録日1995-04-20
公開日1995-09-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of mithramycin dimers bound to partially overlapping sites on DNA.
J.Mol.Biol., 251, 1995
6O6X
DownloadVisualize
BU of 6o6x by Molmil
Crystal structure of Csm6 W14A/E337A mutant in complex with cA4 by cocrystallization
分子名称: Csm6, Cyclic RNA cA4
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6O6S
DownloadVisualize
BU of 6o6s by Molmil
Crystal structure of Apo Csm6
分子名称: Csm6
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6O7H
DownloadVisualize
BU of 6o7h by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system
分子名称: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm2, Csm3, ...
著者Jia, N, Patel, D.J.
登録日2019-03-07
公開日2019-07-31
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019

221716

件を2024-06-26に公開中

PDB statisticsPDBj update infoContact PDBjnumon