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1S9X
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Crystal Structure Analysis of NY-ESO-1 epitope analogue, SLLMWITQA, in complex with HLA-A2
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Webb, A.I, Dunstone, M.A, Chen, W, Aguilar, M.I, Chen, Q, Chang, L, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Rossjohn, J, Purcell, A.W.
登録日2004-02-05
公開日2004-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue
J.Biol.Chem., 279, 2004
6MYF
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Crystal structure of free human Scribble PDZ1 domain
分子名称: Protein scribble homolog
著者Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J.
登録日2018-11-01
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
J.Cell Biol., 218, 2019
1S9W
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Crystal Structure Analysis of NY-ESO-1 epitope, SLLMWITQC, in complex with HLA-A2
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Webb, A.I, Dunstone, M.A, Chen, W, Aguilar, M.I, Chen, Q, Chang, L, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Rossjohn, J, Purcell, A.W.
登録日2004-02-05
公開日2004-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue
J.Biol.Chem., 279, 2004
2IU2
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Recombinant human H ferritin, K86Q, E27D and E107D mutant, soaked with Zn ions
分子名称: FERRITIN HEAVY CHAIN, GLYCEROL, ZINC ION
著者Toussaint, L, Crichton, R.R, Declercq, J.P.
登録日2006-05-26
公開日2006-12-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-Resolution X-Ray Structures of Human Apoferritin H-Chain Mutants Correlated with Their Activity and Metal-Binding Sites.
J.Mol.Biol., 365, 2007
8OL6
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BU of 8ol6 by Molmil
Murine type II Abeta fibril from tgAPPSwe mouse
分子名称: Amyloid-beta protein 42
著者Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F.
登録日2023-03-30
公開日2023-11-29
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
1SI8
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Crystal structure of E. faecalis catalase
分子名称: CHLORIDE ION, Catalase, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Hakansson, K.O, Brugna, M, Tasse, L.
登録日2004-02-28
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The three-dimensional structure of catalase from Enterococcus faecalis.
Acta Crystallogr.,Sect.D, 60, 2004
1RYI
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BU of 1ryi by Molmil
STRUCTURE OF GLYCINE OXIDASE WITH BOUND INHIBITOR GLYCOLATE
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCINE OXIDASE, GLYCOLIC ACID
著者Moertl, M, Diederichs, K, Welte, W, Pollegioni, L, Molla, G, Motteran, L, Andriolo, G, Pilone, M.S.
登録日2003-12-22
公開日2005-02-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-function correlation in glycine oxidase from Bacillus subtilis
J.Biol.Chem., 279, 2004
8OLN
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DI1 Abeta fibril from tg-SwDI mouse
分子名称: Amyloid-beta protein 42
著者Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F.
登録日2023-03-30
公開日2023-11-29
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
8OLQ
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BU of 8olq by Molmil
DI3 Abeta fibril from tg-SwDI mouse
分子名称: Amyloid-beta protein 42
著者Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F.
登録日2023-03-30
公開日2023-11-29
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
8OL3
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Murine type III Abeta fibril from APP/PS1 mouse
分子名称: Amyloid-beta protein 42
著者Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F.
登録日2023-03-30
公開日2023-11-29
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
8OL2
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Murine type II Abeta fibril from APP23 mouse
分子名称: Amyloid-beta protein 42
著者Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F.
登録日2023-03-30
公開日2023-11-29
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
8OL5
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BU of 8ol5 by Molmil
Murine type II Abeta fibril from ARTE10 mouse
分子名称: Amyloid-beta protein 42
著者Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F.
登録日2023-03-30
公開日2023-11-29
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
5NEC
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BU of 5nec by Molmil
Crystal structure of the siderophore receptor PiuD from Pseudomonas aeruginosa
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, TonB-dependent siderophore receptor
著者Moynie, L, Naismith, J.H.
登録日2017-03-10
公開日2018-02-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献TonB-Dependent Receptor Repertoire of Pseudomonas aeruginosa for Uptake of Siderophore-Drug Conjugates.
Antimicrob. Agents Chemother., 62, 2018
8OL7
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BU of 8ol7 by Molmil
MurineArc type I Abeta fibril from tg-APPArcSwe mouse
分子名称: Amyloid-beta protein 42
著者Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F.
登録日2023-03-30
公開日2023-11-29
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
5NHF
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Human Erk2 with an Erk1/2 inhibitor
分子名称: 2-[2-(oxan-4-ylamino)pyrimidin-4-yl]-5-(phenylmethyl)-6,7-dihydro-1~{H}-pyrrolo[3,2-c]pyridin-4-one, Mitogen-activated protein kinase 1, SULFATE ION
著者Debreczeni, J.E, Ward, R.A, Bethel, P, Cook, C, Davies, E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, Hudson, J, James, M, Jones, C.D, Jones, C.R, Lamont, S, Lewis, R, Lindsay, N, Roberts, K, Simpson, I, StGallay, S, Swallow, S, Tonge, M.
登録日2017-03-21
公開日2017-04-19
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point.
J. Med. Chem., 60, 2017
5NHJ
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Human Erk2 with an Erk1/2 inhibitor
分子名称: 5-(2-methoxyethyl)-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydro-1~{H}-pyrrolo[3,2-c]pyridin-4-one, Mitogen-activated protein kinase 1, SULFATE ION
著者Debreczeni, J.E, Ward, R.A, Bethel, P, Cook, C, Davies, E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, Hudson, J, James, M, Jones, C.D, Jones, C.R, Lamont, S, Lewis, R, Lindsay, N, Roberts, K, Simpson, I, StGallay, S, Swallow, S, Tonge, M.
登録日2017-03-21
公開日2017-04-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point.
J. Med. Chem., 60, 2017
8OLG
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BU of 8olg by Molmil
DI2 Abeta fibril from tg-SwDI mouse
分子名称: Amyloid-beta protein 42
著者Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F.
登録日2023-03-30
公開日2023-11-29
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
8OLO
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BU of 8olo by Molmil
Murine type III Abeta fibril from ARTE10 mouse
分子名称: Amyloid-beta protein 42
著者Zielinski, M, Peralta Reyes, F.S, Gremer, L, Schemmert, S, Frieg, B, Willuweit, A, Donner, L, Elvers, M, Nilsson, L.N.G, Syvanen, S, Sehlin, D, Ingelsson, M, Willbold, D, Schroeder, G.F.
登録日2023-03-30
公開日2023-11-29
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease.
Nat.Neurosci., 26, 2023
5NHP
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BU of 5nhp by Molmil
Human Erk2 with an Erk1/2 inhibitor
分子名称: 5-(2-methoxyethyl)-1-methyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydropyrrolo[3,2-c]pyridin-4-one, Mitogen-activated protein kinase 1, SULFATE ION
著者Debreczeni, J.E, Ward, R.A, Bethel, P, Cook, C, Davies, E, Eckersley, K, Fairley, G, Feron, L, Flemington, V, Graham, M.A, Greenwood, R, Hopcroft, P, Howard, T.D, Hudson, J, James, M, Jones, C.D, Jones, C.R, Lamont, S, Lewis, R, Lindsay, N, Roberts, K, Simpson, I, StGallay, S, Swallow, S, Tonge, M.
登録日2017-03-22
公開日2017-04-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structure-Guided Discovery of Potent and Selective Inhibitors of ERK1/2 from a Modestly Active and Promiscuous Chemical Start Point.
J. Med. Chem., 60, 2017
5NLQ
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Auxiliary activity 9
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity 9, CHLORIDE ION, ...
著者Frandsen, K.E.H, Poulsen, J.-C.N, Tandrup, T, Lo Leggio, L.
登録日2017-04-04
公開日2017-11-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates.
Nat Commun, 8, 2017
3NMZ
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BU of 3nmz by Molmil
Crystal structure of APC complexed with Asef
分子名称: APC variant protein, Rho guanine nucleotide exchange factor 4
著者Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G.
登録日2010-06-23
公開日2011-07-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
8B0V
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BU of 8b0v by Molmil
Crystal structure of C-terminal domain of Pseudomonas aeruginosa LexA G91D mutant
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Vascon, F, De Felice, S, Chinellato, M, Maso, L, Cendron, L.
登録日2022-09-08
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural investigations on the SOS response in Pseudomonas aeruginosa
To Be Published
6NC5
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BU of 6nc5 by Molmil
Cronobacter sakazakii (Enterobacter sakazakii) Metallo-beta-lactamse HARLDQ motif
分子名称: ACETATE ION, Beta-lactamase, PHOSPHATE ION, ...
著者Monteiro Pedroso, M, Waite, D, Natasa, M, McGeary, R, Guddat, L, Hugenholtz, P, Schenk, G.
登録日2018-12-10
公開日2019-12-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.074 Å)
主引用文献Broad spectrum antibiotic-degrading metallo-beta-lactamases are phylogenetically diverse.
Protein Cell, 11, 2020
8RGG
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BU of 8rgg by Molmil
Structure of dynein-2 intermediate chain DYNC2I2 (WDR34) in complex with dynein-2 heavy chain DYNC2H1.
分子名称: Cytoplasmic dynein 2 intermediate chain 1, Cytoplasmic dynein 2 intermediate chain 2, Dynein light chain 1, ...
著者Mukhopadhyay, A.G, Toropova, K, Daly, L, Wells, J, Vuolo, L, Mladenov, M, Seda, M, Jenkins, D, Stephens, D.J, Roberts, A.J.
登録日2023-12-13
公開日2024-03-20
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure and tethering mechanism of dynein-2 intermediate chains in intraflagellar transport.
Embo J., 43, 2024
8RGH
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Structure of dynein-2 intermediate chain DYNC2I1 (WDR60) in complex with the dynein-2 heavy chain DYNC2H1.
分子名称: Cytoplasmic dynein 2 intermediate chain 1, Cytoplasmic dynein 2 intermediate chain 2, Cytoplasmic dynein 2 light intermediate chain 1, ...
著者Mukhopadhyay, A.G, Toropova, K, Daly, L, Wells, J, Vuolo, L, Seda, M, Jenkins, D, Stephens, D.J, Roberts, A.J.
登録日2023-12-13
公開日2024-03-20
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure and tethering mechanism of dynein-2 intermediate chains in intraflagellar transport.
Embo J., 43, 2024

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件を2024-07-17に公開中

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