8OL6

Murine type II Abeta fibril from tgAPPSwe mouse

Summary for 8OL6

Entry DOI	10.2210/pdb8ol6/pdb
EMDB information	16952
Descriptor	Amyloid-beta protein 42 (1 entity in total)
Functional Keywords	amyloid fibril, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	10
Total formula weight	45200.87
Authors	Zielinski, M.,Peralta Reyes, F.S.,Gremer, L.,Schemmert, S.,Frieg, B.,Willuweit, A.,Donner, L.,Elvers, M.,Nilsson, L.N.G.,Syvanen, S.,Sehlin, D.,Ingelsson, M.,Willbold, D.,Schroeder, G.F. (deposition date: 2023-03-30, release date: 2023-11-29, Last modification date: 2023-12-13)
Primary citation	Zielinski, M.,Peralta Reyes, F.S.,Gremer, L.,Schemmert, S.,Frieg, B.,Schafer, L.U.,Willuweit, A.,Donner, L.,Elvers, M.,Nilsson, L.N.G.,Syvanen, S.,Sehlin, D.,Ingelsson, M.,Willbold, D.,Schroder, G.F. Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease. Nat.Neurosci., 26:2073-2080, 2023 Cited by PubMed: 37973869 DOI: 10.1038/s41593-023-01484-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation