8OL6
Murine type II Abeta fibril from tgAPPSwe mouse
Summary for 8OL6
Entry DOI | 10.2210/pdb8ol6/pdb |
EMDB information | 16952 |
Descriptor | Amyloid-beta protein 42 (1 entity in total) |
Functional Keywords | amyloid fibril, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 10 |
Total formula weight | 45200.87 |
Authors | Zielinski, M.,Peralta Reyes, F.S.,Gremer, L.,Schemmert, S.,Frieg, B.,Willuweit, A.,Donner, L.,Elvers, M.,Nilsson, L.N.G.,Syvanen, S.,Sehlin, D.,Ingelsson, M.,Willbold, D.,Schroeder, G.F. (deposition date: 2023-03-30, release date: 2023-11-29, Last modification date: 2023-12-13) |
Primary citation | Zielinski, M.,Peralta Reyes, F.S.,Gremer, L.,Schemmert, S.,Frieg, B.,Schafer, L.U.,Willuweit, A.,Donner, L.,Elvers, M.,Nilsson, L.N.G.,Syvanen, S.,Sehlin, D.,Ingelsson, M.,Willbold, D.,Schroder, G.F. Cryo-EM of A beta fibrils from mouse models find tg-APP ArcSwe fibrils resemble those found in patients with sporadic Alzheimer's disease. Nat.Neurosci., 26:2073-2080, 2023 Cited by PubMed: 37973869DOI: 10.1038/s41593-023-01484-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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