8RGG

Structure of dynein-2 intermediate chain DYNC2I2 (WDR34) in complex with dynein-2 heavy chain DYNC2H1.

This is a non-PDB format compatible entry.

Summary for 8RGG

• Entry DOI: 10.2210/pdb8rgg/pdb
• EMDB information: 19132
• Descriptor: Methylated-DNA--protein-cysteine methyltransferase,Cytoplasmic dynein 2 heavy chain 1, Cytoplasmic dynein 2 intermediate chain 1, Cytoplasmic dynein 2 intermediate chain 2, ... (5 entities in total)
• Functional Keywords: dynein, cilia, intraflagellar transport, complex, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 741360.27

Authors

Mukhopadhyay, A.G.,Toropova, K.,Daly, L.,Wells, J.,Vuolo, L.,Mladenov, M.,Seda, M.,Jenkins, D.,Stephens, D.J.,Roberts, A.J. (deposition date: 2023-12-13, release date: 2024-03-20, Last modification date: 2024-04-10)

• Primary citation: Mukhopadhyay, A.G.,Toropova, K.,Daly, L.,Wells, J.N.,Vuolo, L.,Mladenov, M.,Seda, M.,Jenkins, D.,Stephens, D.J.,Roberts, A.J.; Structure and tethering mechanism of dynein-2 intermediate chains in intraflagellar transport.; Embo J., 43:1257-1272, 2024; PubMed: 38454149; DOI: 10.1038/s44318-024-00060-1

Experimental method

ELECTRON MICROSCOPY (4 Å)