6U69
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![BU of 6u69 by Molmil](/molmil-images/mine/6u69) | Crystal structure of Yck2 from Candida albicans, apoenzyme | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-08-29 | 公開日 | 2019-10-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2. Cell Chem Biol, 27, 2020
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6U6A
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![BU of 6u6a by Molmil](/molmil-images/mine/6u6a) | Crystal structure of Yck2 from Candida albicans in complex with kinase inhibitor GW461484A | 分子名称: | 2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine, SULFATE ION, Serine/threonine protein kinase | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Chang, C, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-08-29 | 公開日 | 2019-10-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2. Cell Chem Biol, 27, 2020
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6EDD
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![BU of 6edd by Molmil](/molmil-images/mine/6edd) | Crystal structure of a GNAT Superfamily PA3944 acetyltransferase in complex with CoA (P1 space group) | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Acetyltransferase PA3944, ... | 著者 | Czub, M.P, Porebski, P.J, Majorek, K.A, Satchell, K.J, Joachimiak, A, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-08-09 | 公開日 | 2018-08-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | A Gcn5-Related N-Acetyltransferase (GNAT) Capable of Acetylating Polymyxin B and Colistin Antibiotics in Vitro. Biochemistry, 57, 2018
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6EDV
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![BU of 6edv by Molmil](/molmil-images/mine/6edv) | Structure of a GNAT superfamily acetyltransferase PA3944 in complex with CoA | 分子名称: | 1,2-ETHANEDIOL, Acetyltransferase PA3944, CALCIUM ION, ... | 著者 | Majorek, K.A, Satchell, K.J.F, Joachimiak, A, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-08-12 | 公開日 | 2018-12-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | A Gcn5-Related N-Acetyltransferase (GNAT) Capable of Acetylating Polymyxin B and Colistin Antibiotics in Vitro. Biochemistry, 57, 2018
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6WON
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![BU of 6won by Molmil](/molmil-images/mine/6won) | Crystal structure of acetoin dehydrogenase YohF from Salmonella typhimurium | 分子名称: | CHLORIDE ION, SULFATE ION, YohF | 著者 | Stogios, P.J, Skarina, T, Mesa, N, Endres, M, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-04-25 | 公開日 | 2020-05-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Crystal structure of acetoin dehydrogenase YohF from Salmonella typhimurium To Be Published
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6XNJ
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![BU of 6xnj by Molmil](/molmil-images/mine/6xnj) | Crystal structure of the PDZ domain of human GOPC in complex with a peptide of E. coli O157:H7 str. Sakai effector NleG8 | 分子名称: | Golgi-associated PDZ and coiled-coil motif-containing protein, NleG8 peptide, SULFATE ION | 著者 | Stogios, P.J, Skarina, T, Popov, G, Chang, C, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-07-03 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of the PDZ domain of human GOPC in complex with a peptide of E. coli O157:H7 str. Sakai effector NleG8 To Be Published
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7KES
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![BU of 7kes by Molmil](/molmil-images/mine/7kes) | Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, mutant H168A in complex with apramycin and CoA | 分子名称: | APRAMYCIN, Aminoglycoside N(3)-acetyltransferase, CHLORIDE ION, ... | 著者 | Stogios, P.J, Skarina, T, Michalska, K, Xu, Z, Yim, V, Savchenko, A, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-10-12 | 公開日 | 2020-10-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Commun Biol, 5, 2022
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5BQ9
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![BU of 5bq9 by Molmil](/molmil-images/mine/5bq9) | Crystal structure of uncharacterized protein lpg1496 Legionella pneumophila subsp. pneumophila | 分子名称: | Uncharacterized protein | 著者 | Chang, C, Morar, M, Evdokimova, E, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-05-28 | 公開日 | 2015-06-10 | 最終更新日 | 2016-01-27 | 実験手法 | X-RAY DIFFRACTION (2.2785 Å) | 主引用文献 | Crystal structure of the Legionella pneumophila lem10 effector reveals a new member of the HD protein superfamily. Proteins, 83, 2015
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1K7K
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![BU of 1k7k by Molmil](/molmil-images/mine/1k7k) | crystal structure of RdgB- inosine triphosphate pyrophosphatase from E. coli | 分子名称: | Hypothetical protein yggV | 著者 | Sanishvili, R, Joachimiak, A, Edwards, A, Savchenko, A, Skarina, T, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2001-10-19 | 公開日 | 2002-08-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli. J.Mol.Biol., 374, 2007
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4M3S
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![BU of 4m3s by Molmil](/molmil-images/mine/4m3s) | Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with HEPES | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, SULFATE ION, ... | 著者 | Majorek, K.A, Chruszcz, M, Xu, X, Cymborowski, M, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2013-08-06 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments. Protein Sci., 23, 2014
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2NP3
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![BU of 2np3 by Molmil](/molmil-images/mine/2np3) | Crystal structure of TetR-family regulator (SCO0857) from Streptomyces coelicolor A3. | 分子名称: | Putative TetR-family regulator | 著者 | Koclega, K.D, Xu, X, Chruszcz, M, Gu, J, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-10-26 | 公開日 | 2006-11-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure of TetR-family regulator (SCO0857) from Streptomyces coelicolor A3. To be Published
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2NP5
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![BU of 2np5 by Molmil](/molmil-images/mine/2np5) | Crystal structure of a transcriptional regulator (RHA1_ro04179) from Rhodococcus sp. Rha1. | 分子名称: | DODECYL-BETA-D-MALTOSIDE, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, Transcriptional regulator | 著者 | Chruszcz, M, Evdokimova, E, Kagan, O, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-10-26 | 公開日 | 2006-11-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of a transcriptional regulator (RHA1_ro04179) from Rhodococcus sp. Rha1. TO BE PUBLISHED
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2O0Y
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![BU of 2o0y by Molmil](/molmil-images/mine/2o0y) | Crystal structure of putative transcriptional regulator RHA1_ro06953 (IclR-family) from Rhodococcus sp. | 分子名称: | Transcriptional regulator | 著者 | Chruszcz, M, Wang, S, Skarina, T, Onopriyenko, O, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-11-28 | 公開日 | 2006-12-26 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Putative Transcriptional Regul 2 Rha1_Ro06953(Iclr-Family) from Rhodococcus Sp. To be Published
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1YNB
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![BU of 1ynb by Molmil](/molmil-images/mine/1ynb) | crystal structure of genomics APC5600 | 分子名称: | hypothetical protein AF1432 | 著者 | Dong, A, Skarina, T, Savchenko, A, Pai, E.F, Joachimiak, A, Edwards, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2005-01-24 | 公開日 | 2005-03-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Crystal structure of genomics AF1432 by Sulfur SAD methods To be Published
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1YQH
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![BU of 1yqh by Molmil](/molmil-images/mine/1yqh) | |
1YLM
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![BU of 1ylm by Molmil](/molmil-images/mine/1ylm) | |
1YLX
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![BU of 1ylx by Molmil](/molmil-images/mine/1ylx) | |
7TI9
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![BU of 7ti9 by Molmil](/molmil-images/mine/7ti9) | Crystal structure of the ubiquitin-like domain 1 (Ubl1) of Nsp3 from SARS-CoV-2, form 2 | 分子名称: | CHLORIDE ION, GLYCEROL, Papain-like protease nsp3 | 著者 | Stogios, P.J, Skarina, T, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2022-01-13 | 公開日 | 2022-01-26 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Crystal structure of the ubiquitin-like domain 1 (Ubl1) of Nsp3 from SARS-CoV-2, form 2 To Be Published
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1YX2
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![BU of 1yx2 by Molmil](/molmil-images/mine/1yx2) | |
1YSQ
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![BU of 1ysq by Molmil](/molmil-images/mine/1ysq) | The crystal structure of transcriptional regulator YaiJ | 分子名称: | HTH-type transcriptional regulator yiaJ, PHOSPHATE ION | 著者 | Bochkarev, A, Lunin, V.V, Ezersky, A, Evdokimova, E, Skarina, T, Xu, X, Borek, D, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2005-02-08 | 公開日 | 2005-03-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural study of effector binding specificity in IclR transcriptional regulators To be Published
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1YSP
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![BU of 1ysp by Molmil](/molmil-images/mine/1ysp) | Crystal structure of the C-terminal domain of E. coli transcriptional regulator KdgR. | 分子名称: | SULFATE ION, Transcriptional regulator kdgR | 著者 | Bochkarev, A, Lunin, V.V, Ezersky, A, Evdokimova, E, Skarina, T, Xu, X, Borek, D, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2005-02-08 | 公開日 | 2005-03-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural study of effector binding specificity in IclR transcriptional regulators To be Published
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2ES3
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![BU of 2es3 by Molmil](/molmil-images/mine/2es3) | |
3HYK
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![BU of 3hyk by Molmil](/molmil-images/mine/3hyk) | 2.31 Angstrom resolution crystal structure of a holo-(acyl-carrier-protein) synthase from Bacillus anthracis str. Ames in complex with CoA (3',5'-ADP) | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, CHLORIDE ION, Holo-[acyl-carrier-protein] synthase, ... | 著者 | Halavaty, A.S, Minasov, G, Skarina, T, Onopriyenko, O, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2009-06-22 | 公開日 | 2009-06-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria. Acta Crystallogr.,Sect.D, 68, 2012
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7UUJ
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![BU of 7uuj by Molmil](/molmil-images/mine/7uuj) | Crystal structure of aminoglycoside resistance enzyme ApmA, complex with gentamicin | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 1,2-ETHANEDIOL, Aminocyclitol acetyltransferase ApmA, ... | 著者 | Stogios, P.J, Evdokimova, E, Osipiuk, J, Di Leo, R, Bordeleau, E, Wright, G.D, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID) | 登録日 | 2022-04-28 | 公開日 | 2023-04-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Crystal structure of aminoglycoside resistance enzyme ApmA, complex with gentamicin To Be Published
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7UXG
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![BU of 7uxg by Molmil](/molmil-images/mine/7uxg) | Crystal structure of putative serine protease YdgD from Escherichia coli | 分子名称: | Serine protease | 著者 | Stogios, P.J, Michalska, K, Skarina, T, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2022-05-05 | 公開日 | 2022-05-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Crystal structure of putative serine protease YdgD from Escherichia coli To Be Published
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