6EDV

Structure of a GNAT superfamily acetyltransferase PA3944 in complex with CoA

Summary for 6EDV

• Entry DOI: 10.2210/pdb6edv/pdb
• Related: 6EDD
• Descriptor: Acetyltransferase PA3944, CALCIUM ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: gcn5-related n-acetyltransferase, gnat, pseudomonas aeruginosa, structural genomics, psi-biology, center for structural genomics of infectious diseases, csgid, transferase
• Biological source: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
• Total number of polymer chains: 1
• Total formula weight: 23011.79

Authors

Majorek, K.A.,Satchell, K.J.F.,Joachimiak, A.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2018-08-12, release date: 2018-12-26, Last modification date: 2023-10-11)

• Primary citation: Czub, M.P.,Zhang, B.,Chiarelli, M.P.,Majorek, K.A.,Joe, L.,Porebski, P.J.,Revilla, A.,Wu, W.,Becker, D.P.,Minor, W.,Kuhn, M.L.; A Gcn5-Related N-Acetyltransferase (GNAT) Capable of Acetylating Polymyxin B and Colistin Antibiotics in Vitro.; Biochemistry, 57:7011-7020, 2018; PubMed: 30499668; DOI: 10.1021/acs.biochem.8b00946

Experimental method

X-RAY DIFFRACTION (1.35 Å)