7JTW
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![BU of 7jtw by Molmil](/molmil-images/mine/7jtw) | Crystal structure of RORgt with compound (4R)-6-[(2,5-dichloro-3-{[(2R,4R)-1-(cyclopentanecarbonyl)-2-methylpiperidin-4-yl]oxy}phenyl)amino]-6-oxo-4-phenylhexanoic acid | 分子名称: | (4R)-6-[(2,5-dichloro-3-{[(2R,4R)-1-(cyclopentanecarbonyl)-2-methylpiperidin-4-yl]oxy}phenyl)amino]-6-oxo-4-phenylhexanoic acid, GLYCEROL, RAR-related orphan receptor C isoform a variant, ... | 著者 | Min, X, Wang, Z. | 登録日 | 2020-08-18 | 公開日 | 2021-02-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of 6-Oxo-4-phenyl-hexanoic acid derivatives as ROR gamma t inverse agonists showing favorable ADME profile. Bioorg.Med.Chem.Lett., 36, 2021
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2Q8X
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![BU of 2q8x by Molmil](/molmil-images/mine/2q8x) | The high-resolution crystal structure of ixt6, a thermophilic, intracellular xylanase from G. stearothermophilus | 分子名称: | GLYCEROL, SODIUM ION, intra-cellular xylanase | 著者 | Solomon, V, Teplitsky, A, Gilboa, R, Zolotnitsky, G, Golan, G, Reiland, V, Moryles, S, Shoham, Y, Shoham, G. | 登録日 | 2007-06-12 | 公開日 | 2008-05-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure-specificity relationships of an intracellular xylanase from Geobacillus stearothermophilus Acta Crystallogr.,Sect.D, 63, 2007
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4PN0
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![BU of 4pn0 by Molmil](/molmil-images/mine/4pn0) | |
4PN1
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![BU of 4pn1 by Molmil](/molmil-images/mine/4pn1) | |
3MH8
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![BU of 3mh8 by Molmil](/molmil-images/mine/3mh8) | |
3MHA
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![BU of 3mha by Molmil](/molmil-images/mine/3mha) | Crystal structure of LprG from Mycobacterium tuberculosis bound to PIM | 分子名称: | (1S,2R,3R,4S,5R,6S)-2-(alpha-L-allopyranosyloxy)-3,4,5-trihydroxy-6-({6-O-[(1R)-1-hydroxyhexadecyl]-beta-L-gulopyranosyl}oxy)cyclohexyl (2R)-2-{[(1S)-1-hydroxyhexadecyl]oxy}-3-{[(1S,10S)-1-hydroxy-10-methyloctadecyl]oxy}propyl hydrogen (R)-phosphate, Lipoprotein lprG | 著者 | Tsai, H.-C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-04-07 | 公開日 | 2010-09-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2. Nat.Struct.Mol.Biol., 17, 2010
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2HVQ
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![BU of 2hvq by Molmil](/molmil-images/mine/2hvq) | Structure of Adenylated full-length T4 RNA Ligase 2 | 分子名称: | Hypothetical 37.6 kDa protein in Gp24-hoc intergenic region, MAGNESIUM ION | 著者 | Nandakumar, J, Lima, C.D. | 登録日 | 2006-07-30 | 公開日 | 2006-10-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward. Cell(Cambridge,Mass.), 127, 2006
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2HVS
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![BU of 2hvs by Molmil](/molmil-images/mine/2hvs) | Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 2'-deoxyribonucleotide at the nick | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*TP*TP*G)-3', 5'-D(*CP*AP*AP*TP*TP*GP*CP*GP*AP*C)-R(P*(OMC)P*C)-3', ... | 著者 | Nandakumar, J, Lima, C.D. | 登録日 | 2006-07-30 | 公開日 | 2006-10-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward. Cell(Cambridge,Mass.), 127, 2006
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2HVR
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![BU of 2hvr by Molmil](/molmil-images/mine/2hvr) | Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 3'-deoxyribonucleotide at the nick | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*TP*TP*G)-3', 5'-D(*CP*AP*AP*TP*TP*GP*CP*GP*AP*C)-R(P*(OMC)P*C)-3', ... | 著者 | Nandakumar, J, Lima, C.D. | 登録日 | 2006-07-30 | 公開日 | 2006-10-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward. Cell(Cambridge,Mass.), 127, 2006
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3EF1
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![BU of 3ef1 by Molmil](/molmil-images/mine/3ef1) | |
3EF0
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![BU of 3ef0 by Molmil](/molmil-images/mine/3ef0) | |
4LOH
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![BU of 4loh by Molmil](/molmil-images/mine/4loh) | Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(3',5')p] | 分子名称: | Stimulator of interferon genes protein, cGAMP | 著者 | Gao, P, Patel, D.J. | 登録日 | 2013-07-12 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOJ
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![BU of 4loj by Molmil](/molmil-images/mine/4loj) | Crystal structure of mSting in complex with c[G(2',5')pA(3',5')p] | 分子名称: | Stimulator of interferon genes protein, cGAMP | 著者 | Gao, P, Patel, D.J. | 登録日 | 2013-07-12 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOI
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![BU of 4loi by Molmil](/molmil-images/mine/4loi) | Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(2',5')p] | 分子名称: | 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one, PHOSPHATE ION, Stimulator of interferon genes protein | 著者 | Gao, P, Patel, D.J. | 登録日 | 2013-07-12 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOK
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![BU of 4lok by Molmil](/molmil-images/mine/4lok) | Crystal structure of mSting in complex with c[G(3',5')pA(3',5')p] | 分子名称: | 2-amino-9-[(2R,3R,3aR,5S,7aS,9R,10R,10aR,12R,14aS)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon genes protein | 著者 | Gao, P, Patel, D.J. | 登録日 | 2013-07-12 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOL
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![BU of 4lol by Molmil](/molmil-images/mine/4lol) | Crystal structure of mSting in complex with DMXAA | 分子名称: | (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein | 著者 | Gao, P, Patel, D.J. | 登録日 | 2013-07-12 | 公開日 | 2013-08-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4PZ7
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![BU of 4pz7 by Molmil](/molmil-images/mine/4pz7) | PCE1 guanylyltransferase | 分子名称: | GLYCEROL, SULFATE ION, mRNA-capping enzyme subunit alpha | 著者 | Doamekpor, S.K, Lima, C.D. | 登録日 | 2014-03-28 | 公開日 | 2014-06-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.109 Å) | 主引用文献 | How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes. Genes Dev., 28, 2014
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4PZ8
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![BU of 4pz8 by Molmil](/molmil-images/mine/4pz8) | PCE1 guanylyltransferase bound to SPT5 CTD | 分子名称: | SULFATE ION, Transcription elongation factor spt5, mRNA-capping enzyme subunit alpha | 著者 | Doamekpor, S.K, Lima, C.D. | 登録日 | 2014-03-28 | 公開日 | 2014-06-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes. Genes Dev., 28, 2014
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4PZ6
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![BU of 4pz6 by Molmil](/molmil-images/mine/4pz6) | |
3RTX
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![BU of 3rtx by Molmil](/molmil-images/mine/3rtx) | |
3U4H
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![BU of 3u4h by Molmil](/molmil-images/mine/3u4h) | CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template | 分子名称: | 8-Amino-N1-Cyclic Inosine 5'-Diphosphoribose, ADP-ribosyl cyclase 1 | 著者 | Liu, Q, Hao, Q, Lee, H.C, Graeff, R. | 登録日 | 2011-10-08 | 公開日 | 2012-10-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.878 Å) | 主引用文献 | CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template Plos One, 8, 2013
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3U4I
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![BU of 3u4i by Molmil](/molmil-images/mine/3u4i) | CD38 structure-based inhibitor design using the N1-cyclic inosine 5'-diphosphate ribose template | 分子名称: | ADP-ribosyl cyclase 1, Cyclic adenosine 5'-diphosphocarbocyclic ribose | 著者 | Liu, Q, Hao, Q, Lee, H.C, Graeff, R. | 登録日 | 2011-10-08 | 公開日 | 2012-10-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.118 Å) | 主引用文献 | CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template Plos One, 8, 2013
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2GAT
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![BU of 2gat by Molmil](/molmil-images/mine/2gat) | SOLUTION STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, NMR, REGULARIZED MEAN STRUCTURE | 分子名称: | DNA (5'-D(*AP*AP*TP*GP*TP*TP*TP*AP*TP*CP*TP*GP*CP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*GP*CP*AP*GP*AP*TP*AP*AP*AP*CP*AP*TP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1, ... | 著者 | Clore, G.M, Tjandra, N, Starich, M, Omichinski, J.G, Gronenborn, A.M. | 登録日 | 1997-11-07 | 公開日 | 1998-01-28 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solution. Nat.Struct.Biol., 4, 1997
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3GAT
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![BU of 3gat by Molmil](/molmil-images/mine/3gat) | SOLUTION NMR STRUCTURE OF THE C-TERMINAL DOMAIN OF CHICKEN GATA-1 BOUND TO DNA, 34 STRUCTURES | 分子名称: | DNA (5'-D(*AP*AP*TP*GP*TP*TP*TP*AP*TP*CP*TP*GP*CP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*GP*CP*AP*GP*AP*TP*AP*AP*AP*CP*AP*TP*T)-3'), ERYTHROID TRANSCRIPTION FACTOR GATA-1, ... | 著者 | Clore, G.M, Tjandra, N, Starich, M, Omichinski, J.G, Gronenborn, A.M. | 登録日 | 1997-11-07 | 公開日 | 1998-01-28 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Use of dipolar 1H-15N and 1H-13C couplings in the structure determination of magnetically oriented macromolecules in solution. Nat.Struct.Biol., 4, 1997
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