4OVA
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4RIK
| Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77 | 分子名称: | Alpha-synuclein | 著者 | Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S. | 登録日 | 2014-10-06 | 公開日 | 2015-08-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.854 Å) | 主引用文献 | Structure of the toxic core of alpha-synuclein from invisible crystals. Nature, 525, 2015
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3PPD
| GGVLVN segment from Human Prostatic Acid Phosphatase Residues 260-265, involved in Semen-Derived Enhancer of Viral Infection | 分子名称: | ACETIC ACID, GGVLVN peptide, amyloid forming segment, ... | 著者 | Zhao, A, Sawaya, M.R, Eisenberg, D. | 登録日 | 2010-11-24 | 公開日 | 2011-06-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation. Nature, 475, 2011
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5W0W
| Crystal structure of Protein Phosphatase 2A bound to TIPRL | 分子名称: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... | 著者 | Wu, C, Zheng, A, Li, J, Satyshur, K, Xing, Y. | 登録日 | 2017-06-01 | 公開日 | 2018-01-17 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Methylation-regulated decommissioning of multimeric PP2A complexes. Nat Commun, 8, 2017
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5W0X
| Crystal structure of mouse TOR signaling pathway regulator-like (TIPRL) delta 94-103 | 分子名称: | TIP41-like protein | 著者 | Wu, C, Zheng, A, Li, J, Satyshur, K, Xing, Y. | 登録日 | 2017-06-01 | 公開日 | 2018-01-17 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.717 Å) | 主引用文献 | Methylation-regulated decommissioning of multimeric PP2A complexes. Nat Commun, 8, 2017
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7XUZ
| Crystal structure of a HDAC4-MEF2A-DNA ternary complex | 分子名称: | DNA (5'-D(*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*T)-3'), DNA (5'-D(P*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*A)-3'), Histone deacetylase 4, ... | 著者 | Dai, S.Y, Guo, L, Dey, R, Guo, M, Bates, D, Cayford, J, Chen, X.J, Wei, X.D, Chen, L, Chen, Y.H. | 登録日 | 2022-05-20 | 公開日 | 2023-11-29 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (3.591 Å) | 主引用文献 | Structural insights into the HDAC4-MEF2A-DNA complex and its implication in long-range transcriptional regulation. Nucleic Acids Res., 52, 2024
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5XN5
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5Z9R
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5ZHH
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6ITE
| Crystal structure of group A Streptococcal surface dehydrogenase (SDH) | 分子名称: | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | 著者 | Yuan, C, Li, R, Huang, M.D. | 登録日 | 2018-11-21 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.739 Å) | 主引用文献 | Structural determination of group A Streptococcal surface dehydrogenase and characterization of its interaction with urokinase-type plasminogen activator receptor. Biochem.Biophys.Res.Commun., 510, 2019
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7DHT
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7D5O
| C-Src in complex with TAS-120 | 分子名称: | 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one, Proto-oncogene tyrosine-protein kinase Src | 著者 | Qu, L.Z, Chen, Y.H. | 登録日 | 2020-09-27 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors Commun Chem, 5, 2022
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7E17
| Structure of dimeric uPAR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | 著者 | Cai, Y, Huang, M. | 登録日 | 2021-02-01 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Crystal structure and cellular functions of uPAR dimer Nat Commun, 13, 2022
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7XV6
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7XVA
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7XV9
| Crystal structure of the Human TR4 DNA-Binding Domain | 分子名称: | Nuclear receptor subfamily 2 group C member 2, ZINC ION | 著者 | Liu, Y, Chen, Z. | 登録日 | 2022-05-21 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation. Nucleic Acids Res., 51, 2023
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7XV8
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7F3M
| Crystal structure of FGFR4 kinase domain with PRN1371 | 分子名称: | 6-[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]-2-(methylamino)-8-[3-(4-prop-2-enoylpiperazin-1-yl)propyl]pyrido[2,3-d]pyrimidin-7-one, Fibroblast growth factor receptor 4, SULFATE ION | 著者 | Chen, X.J, Qu, L.Z, Dai, S.Y, Wei, H.D, Chen, Y.H. | 登録日 | 2021-06-16 | 公開日 | 2022-01-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.289 Å) | 主引用文献 | Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors Commun Chem, 5, 2022
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7D57
| C-Src in complex with FIIN-2 | 分子名称: | N-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)propanamide, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION | 著者 | Chen, Y.H, Qu, L.Z. | 登録日 | 2020-09-25 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors Commun Chem, 5, 2022
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7XP5
| Cryo-EM structure of a class T GPCR in ligand-free state | 分子名称: | Endoglucanase H,Taste receptor type 2 member 46,Bitter taste receptor T2R46, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.J, Hua, T, Xu, W.X, Wu, L.J. | 登録日 | 2022-05-03 | 公開日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structural basis for strychnine activation of human bitter taste receptor TAS2R46. Science, 377, 2022
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7XP6
| Cryo-EM structure of a class T GPCR in active state | 分子名称: | Endoglucanase H,Taste receptor type 2 member 46,Endoglucanase H,Taste receptor type 2 member 46,Bitter taste receptor T2R46, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.J, Hua, T, Xu, W.X, Wu, L.J. | 登録日 | 2022-05-03 | 公開日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural basis for strychnine activation of human bitter taste receptor TAS2R46. Science, 377, 2022
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7XP4
| Cryo-EM structure of a class T GPCR in apo state | 分子名称: | Endoglucanase H,Taste receptor type 2 member 46,Endoglucanase H,Taste receptor type 2 member 46,Bitter taste receptor T2R46, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, Z.J, Hua, T, Xu, W.X, Wu, L.J. | 登録日 | 2022-05-03 | 公開日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural basis for strychnine activation of human bitter taste receptor TAS2R46. Science, 377, 2022
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7XT1
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7VM5
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7VM6
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