6LBI
Crystal Structure of FOXO1-DBD homodimer bound to a palindromic DNA sequence
Summary for 6LBI
| Entry DOI | 10.2210/pdb6lbi/pdb |
| Descriptor | IRE0, Forkhead box protein O1 (2 entities in total) |
| Functional Keywords | transcription factor, foxo1, protein-dna complex, dna binding, dna binding protein |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 12 |
| Total formula weight | 116122.95 |
| Authors | Li, J.,Dai, S.Y.,Chen, Y.H. (deposition date: 2019-11-14, release date: 2021-02-10, Last modification date: 2023-11-22) |
| Primary citation | Li, J.,Dai, S.,Chen, X.,Liang, X.,Qu, L.,Jiang, L.,Guo, M.,Zhou, Z.,Wei, H.,Zhang, H.,Chen, Z.,Chen, L.,Chen, Y. Mechanism of forkhead transcription factors binding to a novel palindromic DNA site. Nucleic Acids Res., 49:3573-3583, 2021 Cited by PubMed: 33577686DOI: 10.1093/nar/gkab086 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.067 Å) |
Structure validation
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