8H0F
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8H0E
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8GZO
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2OFS
| Crystal structure of human CD59 | 分子名称: | CD59 glycoprotein | 著者 | Davies, C. | 登録日 | 2007-01-04 | 公開日 | 2007-05-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex. Acta Crystallogr.,Sect.D, 63, 2007
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6XEY
| Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-4 | 分子名称: | 2-4 Heavy Chain, 2-4 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Rapp, M, Shapiro, L, Ho, D.D. | 登録日 | 2020-06-14 | 公開日 | 2020-07-22 | 最終更新日 | 2021-01-27 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike. Nature, 584, 2020
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3TYQ
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3TYV
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5JDH
| Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 10 mM Na+ and 10mM Ca2+ | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CALCIUM ION, ... | 著者 | Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D. | 登録日 | 2016-04-16 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | 主引用文献 | Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger. Nat.Struct.Mol.Biol., 23, 2016
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5JDN
| Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 10 mM Na+ and 10mM Sr2+ | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PENTADECANE, PENTAETHYLENE GLYCOL, ... | 著者 | Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D. | 登録日 | 2016-04-17 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger. Nat.Struct.Mol.Biol., 23, 2016
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5JDM
| Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 0.1mM Sr2+ | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15-PENTAOXAHEPTADECANE, PENTADECANE, ... | 著者 | Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D. | 登録日 | 2016-04-17 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.558 Å) | 主引用文献 | Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger. Nat.Struct.Mol.Biol., 23, 2016
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5JDG
| Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 0.1mM Ca2+ | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D. | 登録日 | 2016-04-16 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.407 Å) | 主引用文献 | Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger. Nat.Struct.Mol.Biol., 23, 2016
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5JDL
| Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 1mM Sr2+ | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, PENTADECANE, ... | 著者 | Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D. | 登録日 | 2016-04-17 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.904 Å) | 主引用文献 | Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger. Nat.Struct.Mol.Biol., 23, 2016
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4N75
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7SI2
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7SD5
| Crystallographic structure of neutralizing antibody 10-40 in complex with SARS-CoV-2 spike receptor binding domain | 分子名称: | 10-40 Heavy chain, 10-40 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Reddem, E.R, Casner, R.G, Shapiro, L. | 登録日 | 2021-09-29 | 公開日 | 2022-04-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses. Sci Transl Med, 14, 2022
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1WJF
| SOLUTION STRUCTURE OF H12C MUTANT OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE COMPLEXED TO CADMIUM, NMR, 40 STRUCTURES | 分子名称: | CADMIUM ION, HIV-1 INTEGRASE | 著者 | Cai, M, Gronenborn, A.M, Clore, G.M. | 登録日 | 1998-06-11 | 公開日 | 1998-12-16 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the His12 --> Cys mutant of the N-terminal zinc binding domain of HIV-1 integrase complexed to cadmium. Protein Sci., 7, 1998
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7YP2
| Cryo-EM structure of EBV gHgL-gp42 in complex with mAb 6H2 (localized refinement) | 分子名称: | 6H2 heavy chain, 6H2 light chain, Envelope glycoprotein H | 著者 | Liu, L, Sun, H, Jiang, Y, Hong, J, Zheng, Q, Li, S, Chen, Y, Xia, N. | 登録日 | 2022-08-02 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection. Cell Rep Med, 4, 2023
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7YOY
| Cryo-EM structure of EBV gHgL-gp42 in complex with mAbs 3E8 and 5E3 (localized refinement) | 分子名称: | 3E8 heavy chain, 3E8 light chain, 5E3 heavy chain, ... | 著者 | Liu, L, Sun, H, Jiang, Y, Hong, J, Zheng, Q, Li, S, Chen, Y, Xia, N. | 登録日 | 2022-08-02 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection. Cell Rep Med, 4, 2023
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7YP1
| Cryo-EM structure of EBV gHgL-gp42 in complex with mAb 10E4 (localized refinement) | 分子名称: | 10E4 heavy chain, 10E4 light chain, EBV gH, ... | 著者 | Liu, L, Sun, H, Jiang, Y, Hong, J, Zheng, Q, Li, S, Chen, Y, Xia, N. | 登録日 | 2022-08-02 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection. Cell Rep Med, 4, 2023
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2QRA
| Crystal structure of XIAP BIR1 domain (P21 form) | 分子名称: | Baculoviral IAP repeat-containing protein 4, ETHANOL, ZINC ION | 著者 | Lin, S.-C. | 登録日 | 2007-07-27 | 公開日 | 2007-09-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the BIR1 domain of XIAP in two crystal forms J.Mol.Biol., 372, 2007
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6XAE
| SUBSTITUTED BENZYLOXYTRICYCLIC COMPOUNDS AS RETINOIC ACID-RELATED ORPHAN RECEPTOR GAMMA T AGONISTS | 分子名称: | Nuclear receptor ROR-gamma, trans-4-{(3aR,9bR)-7-[(2-chloro-6-fluorophenyl)methoxy]-9b-[(4-fluorophenyl)sulfonyl]-1,2,3a,4,5,9b-hexahydro-3H-benzo[e]indole-3-carbonyl}cyclohexane-1-carboxylic acid | 著者 | Sack, J.S. | 登録日 | 2020-06-04 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.257 Å) | 主引用文献 | Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (ROR gamma t) agonists. Bioorg.Med.Chem.Lett., 30, 2020
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8IER
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8IL3
| Cryo-EM structure of CD38 in complex with FTL004 | 分子名称: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Heavy chain, Light chain | 著者 | Yang, J, Wang, Y, Zhang, G. | 登録日 | 2023-03-01 | 公開日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | FTL004, an anti-CD38 mAb with negligible RBC binding and enhanced pro-apoptotic activity, is a novel candidate for treatments of multiple myeloma and non-Hodgkin lymphoma. J Hematol Oncol, 15, 2022
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4Y87
| Crystal structure of phosphodiesterase 9 in complex with (R)-C33 (6-{[(1R)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) | 分子名称: | 6-{[(1R)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | 著者 | Huang, M. | 登録日 | 2015-02-16 | 公開日 | 2015-09-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol.Pharmacol., 88, 2015
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4Y86
| Crystal structure of PDE9 in complex with racemic inhibitor C33 | 分子名称: | 6-{[(1R)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, 6-{[(1S)-1-(4-chlorophenyl)ethyl]amino}-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ... | 著者 | Huang, M. | 登録日 | 2015-02-16 | 公開日 | 2015-09-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol.Pharmacol., 88, 2015
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