5JDN

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 10 mM Na+ and 10mM Sr2+

Summary for 5JDN

Entry DOI	10.2210/pdb5jdn/pdb
Related	5HWX 5HWY 5HXC 5HXE 5HXH 5HXR 5HXS 5HYA 5JDF 5JDG 5JDH 5JDL 5JDM 5JDQ
Descriptor	sodium-calcium exchanger NCX_Mj, SODIUM ION, STRONTIUM ION, ... (7 entities in total)
Functional Keywords	na+/ca2+ exchange, calcium signalling, membrane transporter, induced conformational change, membrane protein
Biological source	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Total number of polymer chains	1
Total formula weight	34667.32
Authors	Liao, J.,Jiang, Y.X.,Faraldo-Gomez, J.D. (deposition date: 2016-04-17, release date: 2016-05-11, Last modification date: 2023-09-27)
Primary citation	Liao, J.,Marinelli, F.,Lee, C.,Huang, Y.,Faraldo-Gomez, J.D.,Jiang, Y. Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger. Nat.Struct.Mol.Biol., 23:590-599, 2016 Cited by PubMed: 27183196 DOI: 10.1038/nsmb.3230 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation