5JDL

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 1mM Sr2+

Summary for 5JDL

Entry DOI	10.2210/pdb5jdl/pdb
Related	5HWX 5HWY 5HXC 5HXE 5HXH 5HXR 5HXS 5HYA 5JDF 5JDG 5JDH 5JDM 5JDN 5JDQ
Descriptor	Uncharacterized membrane protein MJ0091, STRONTIUM ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	na+/ca2+ exchange, calcium signalling, membrane transporter, induced conformational change, membrane protein
Biological source	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Total number of polymer chains	1
Total formula weight	34672.70
Authors	Liao, J.,Jiang, Y.X.,Faraldo-Gomez, J.D. (deposition date: 2016-04-17, release date: 2016-05-11, Last modification date: 2023-09-27)
Primary citation	Liao, J.,Marinelli, F.,Lee, C.,Huang, Y.,Faraldo-Gomez, J.D.,Jiang, Y. Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger. Nat.Struct.Mol.Biol., 23:590-599, 2016 Cited by PubMed: 27183196 DOI: 10.1038/nsmb.3230 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.904 Å)

Structure validation