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7XME
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BU of 7xme by Molmil
Structure of Influenza A virus polymerase basic protein 2 (PB2) with an azazindole derivative
分子名称: (2~{S},3~{S})-3-[[5-dimethoxyphosphoryl-4-(5-fluoranyl-1~{H}-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, IODIDE ION, Polymerase basic protein 2
著者Zhang, Z.
登録日2022-04-25
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.521 Å)
主引用文献Discovery of a novel azaindole derivatives targeting the influenza PB2 cap binding region
To Be Published
7VGR
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BU of 7vgr by Molmil
SARS-CoV-2 M protein dimer (long form) in complex with YN7756_1 Fab
分子名称: Membrane protein, YN7756_1 Fab heavy chain, YN7756_1 Fab light chain
著者Zhang, Z, Ohto, U, Shimizu, T.
登録日2021-09-18
公開日2022-08-03
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structure of SARS-CoV-2 membrane protein essential for virus assembly.
Nat Commun, 13, 2022
7VGS
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BU of 7vgs by Molmil
SARS-CoV-2 M protein dimer (short form) in complex with YN7717_9 Fab
分子名称: Membrane protein, YN7717_9 Fab heavy chain, YN7717_9 Fab light chain
著者Zhang, Z, Ohto, U, Shimizu, T.
登録日2021-09-18
公開日2022-08-03
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of SARS-CoV-2 membrane protein essential for virus assembly.
Nat Commun, 13, 2022
8ZMR
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BU of 8zmr by Molmil
Vesamicol-bound VAChT
分子名称: Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7, vesamicol
著者Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H.
登録日2024-05-23
公開日2024-06-19
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into VAChT neurotransmitter recognition and inhibition.
Cell Res., 34, 2024
8ZMS
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BU of 8zms by Molmil
Acetylcholine-bound VAChT
分子名称: ACETYLCHOLINE, Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7
著者Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H.
登録日2024-05-23
公開日2024-06-19
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insights into VAChT neurotransmitter recognition and inhibition.
Cell Res., 34, 2024
8WH0
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BU of 8wh0 by Molmil
MPOX E5 hexamer ssDNA and AMP-PNP bound conformation
分子名称: DNA (5'-D(P*CP*CP*CP*CP*C)-3'), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Zhang, Z, Dong, C.
登録日2023-09-22
公開日2024-10-09
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Essential and multifunctional mpox virus E5 helicase-primase in double and single hexamer.
Sci Adv, 10, 2024
8WH3
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BU of 8wh3 by Molmil
MPOX E5 hexamer apo form
分子名称: Uncoating factor OPG117
著者Zhang, Z, Dong, C.
登録日2023-09-22
公開日2024-09-25
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Essential and multifunctional mpox virus E5 helicase-primase in double and single hexamer.
Sci Adv, 10, 2024
8WH4
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BU of 8wh4 by Molmil
MPOX E5 hexamer ssDNA bound apo conformation
分子名称: DNA (5'-D(P*CP*CP*CP*C)-3'), Uncoating factor OPG117
著者Zhang, Z, Dong, C.
登録日2023-09-22
公開日2024-09-25
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Essential and multifunctional mpox virus E5 helicase-primase in double and single hexamer.
Sci Adv, 10, 2024
8WH6
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BU of 8wh6 by Molmil
MPOX E5 hexamer ADP and ssDNA bound and clear primase domain conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*CP*CP*C)-3'), Uncoating factor OPG117, ...
著者Zhang, Z, Dong, C.
登録日2023-09-22
公開日2024-09-25
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Essential and multifunctional mpox virus E5 helicase-primase in double and single hexamer.
Sci Adv, 10, 2024
5H93
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BU of 5h93 by Molmil
Crystal structure of Geobacter metallireducens SMUG1
分子名称: Geobacter metallireducens SMUG1
著者Xie, W, Cao, W, Zhang, Z, Shen, J.
登録日2015-12-25
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.176 Å)
主引用文献Structural Basis of Substrate Specificity in Geobacter metallireducens SMUG1
Acs Chem.Biol., 11, 2016
5H98
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BU of 5h98 by Molmil
Crystal structure of Geobacter metallireducens SMUG1
分子名称: Geobacter metallireducens SMUG1
著者Xie, W, Cao, W, Zhang, Z, Shen, J.
登録日2015-12-26
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural Basis of Substrate Specificity in Geobacter metallireducens SMUG1
Acs Chem.Biol., 11, 2016
8WX2
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BU of 8wx2 by Molmil
Cryo-EM structure of human SLC15A3 (dimer)
分子名称: Solute carrier family 15 member 3
著者Kasai, S, Zhang, Z, Ohto, U, Shimizu, T.
登録日2023-10-27
公開日2023-12-06
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Cryo-EM structure of human SLC15A3 (outward-facing partially occluded)
To Be Published
8WX3
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BU of 8wx3 by Molmil
Cryo-EM structure of human SLC15A4 (outward-facing open)
分子名称: Solute carrier family 15 member 4
著者Sakaniwa, K, Zhang, Z, Ohto, U, Shimizu, T.
登録日2023-10-27
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Cryo-EM structure of human SLC15A4 (outward-facing open)
To Be Published
8WX5
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BU of 8wx5 by Molmil
Cryo-EM structure of human SLC15A4 in complex with TASL (inward-facing open)
分子名称: Solute carrier family 15 member 4, TASL (TASL-SLC15A4 fusion protein)
著者Ohto, U, Zhang, Z, Fujimura, A, Shimizu, T.
登録日2023-10-27
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Cryo-EM structure of human SLC15A4 in complex with TASL (inward-facing open)
To Be Published
8WX4
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BU of 8wx4 by Molmil
Cryo-EM structure of human SLC15A4 in complex with Lys-Leu (outward-facing open)
分子名称: LEUCINE, LYSINE, Solute carrier family 15 member 4
著者Sakaniwa, K, Zhang, Z, Ohto, U, Shimizu, T.
登録日2023-10-27
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Cryo-EM structure of human SLC15A4 in complex with Lys-Leu (outward-facing open)
To Be Published
8HIK
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BU of 8hik by Molmil
The TPP-bound BRIL-SLC19A1/Fab/Nb ternary complex
分子名称: Anti-BRIL Fab heavy chain, Anti-BRIL Fab light chain, Anti-Fab nanobody, ...
著者Zhang, Z, Dang, Y.
登録日2022-11-20
公開日2022-12-21
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Molecular mechanism of substrate recognition by folate transporter SLC19A1.
Cell Discov, 8, 2022
8HII
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BU of 8hii by Molmil
The BRIL-SLC19A1/Fab/Nb ternary complex
分子名称: BRIL-SLC19A1 chimera, anti-BRIL Fab heavy chain, anti-BRIL Fab light chain, ...
著者Zhang, Z, Dang, Y.
登録日2022-11-20
公開日2022-12-21
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Molecular mechanism of substrate recognition by folate transporter SLC19A1.
Cell Discov, 8, 2022
8HGO
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BU of 8hgo by Molmil
The EGF-bound EGFR/HER2 ectodomain complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor, ...
著者Zhang, Z, Bai, X.
登録日2022-11-15
公開日2023-02-08
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献Structure and dynamics of the EGFR/HER2 heterodimer.
Cell Discov, 9, 2023
8HGP
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BU of 8hgp by Molmil
The EREG-bound EGFR/HER2 ectodomain complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
著者Zhang, Z, Bai, X.
登録日2022-11-15
公開日2023-02-08
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (4.53 Å)
主引用文献Structure and dynamics of the EGFR/HER2 heterodimer.
Cell Discov, 9, 2023
8HGS
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BU of 8hgs by Molmil
The EGF-bound EGFR ectodomain homodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, Pro-epidermal growth factor, ...
著者Zhang, Z, Bai, X.
登録日2022-11-15
公開日2023-02-15
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3.81 Å)
主引用文献Structure and dynamics of the EGFR/HER2 heterodimer.
Cell Discov, 9, 2023
6K10
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BU of 6k10 by Molmil
Non substrate bound state of Staphylococcus Aureus AldH
分子名称: 1,2-ETHANEDIOL, Aldehyde dehydrogenase
著者Zhang, Z, Tao, X.
登録日2019-05-08
公開日2020-05-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.78962183 Å)
主引用文献Structural Insight into the Substrate Gating Mechanism by Staphylococcus aureus Aldehyde Dehydrogenase
CCS Chemistry, 2, 2020
6K9H
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BU of 6k9h by Molmil
Human LXR-beta in complex with an agonist
分子名称: Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-phenyl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate
著者Zhang, Z, Zhou, H.
登録日2019-06-15
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of new LXR beta agonists as glioblastoma inhibitors.
Eur.J.Med.Chem., 194, 2020
6K0Z
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BU of 6k0z by Molmil
Substrate bound state of Staphylococcus Aureus AldH
分子名称: 1,2-ETHANEDIOL, Aldehyde dehydrogenase, GLYCEROL
著者Zhang, Z, Tao, X.
登録日2019-05-08
公開日2020-05-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.4967258 Å)
主引用文献Structural Insight into the Substrate Gating Mechanism by Staphylococcus aureus Aldehyde Dehydrogenase
CCS Chemistry, 2, 2020
6K9G
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BU of 6k9g by Molmil
Human LXR-beta in complex with an agonist
分子名称: Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{R},3~{R})-2'-[3-[4-(hydroxymethyl)-3-methylsulfonyl-phenyl]phenyl]-2-oxidanylidene-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate
著者Zhang, Z, Zhou, H.
登録日2019-06-15
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of new LXR beta agonists as glioblastoma inhibitors.
Eur.J.Med.Chem., 194, 2020
6K9M
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BU of 6k9m by Molmil
Human LXR-beta in complex with an agonist
分子名称: Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-propan-2-yl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate
著者Zhang, Z, Zhou, H.
登録日2019-06-16
公開日2020-06-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discovery of novel liver X receptor inverse agonists as lipogenesis inhibitors.
Eur.J.Med.Chem., 206, 2020

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件を2024-10-16に公開中

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