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2RB6
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BU of 2rb6 by Molmil
X-Ray structure of the protein Q8EI81. Northeast Structural Genomics Consortium target SoR78A
分子名称: Uncharacterized protein
著者Kuzin, A.P, Su, M, Seetharaman, J, Vorobiev, S.M, Wang, H, Mao, L, Cunningham, K, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2007-09-18
公開日2007-10-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-Ray structure of the protein Q8EI81.
To be Published
2RAL
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BU of 2ral by Molmil
Crystal Structure Analysis of double cysteine mutant of S.epidermidis adhesin SdrG: Evidence for the Dock,Lock and Latch ligand binding mechanism
分子名称: Serine-aspartate repeat-containing protein G
著者Ponnuraj, K, Sthanam, N, Bowden, M.G, Hook, M.
登録日2007-09-17
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Evidence for the "dock, lock, and latch" ligand binding mechanism of the staphylococcal microbial surface component recognizing adhesive matrix molecules (MSCRAMM) SdrG.
J.Biol.Chem., 283, 2008
4URY
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BU of 4ury by Molmil
The crystal structure of H-Ras and SOS in complex with ligands
分子名称: GTPASE HRAS, N-[(4-aminophenyl)sulfonyl]cyclopropanecarboxamide, SON OF SEVENLESS HOMOLOG 1
著者Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G.
登録日2014-07-02
公開日2015-03-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation.
J.Med.Chem., 58, 2015
2RD4
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BU of 2rd4 by Molmil
Design of specific inhibitors of Phospholipase A2: Crystal structure of the complex of phospholipase A2 with pentapeptide Leu-Val-Phe-Phe-Ala at 2.9 A resolution
分子名称: CALCIUM ION, Phospholipase A2 isoform 1, Phospholipase A2 isoform 2, ...
著者Mirza, Z, Kaur, A, Singh, N, Sinha, M, Sharma, S, Srinivasan, A, Kaur, P, Singh, T.P.
登録日2007-09-21
公開日2007-10-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Design of specific inhibitors of Phospholipase A2: Crystal structure of the complex of phospholipase A2 with pentapeptide Leu-Val-Phe-Phe-Ala at 2.9 A resolution
To be Published
4V0T
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BU of 4v0t by Molmil
Monomeric pseudorabies virus protease pUL26N at 2.1 A resolution
分子名称: UL26
著者Zuehlsdorf, M, Werten, S, Palm, G.J, Hinrichs, W.
登録日2014-09-18
公開日2015-07-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin Pul26N, a Herpesvirus Serine Protease
Plos Pathog., 11, 2015
4V4T
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BU of 4v4t by Molmil
Crystal structure of the whole ribosomal complex with a stop codon in the A-site.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
登録日2005-10-12
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (6.46 Å)
主引用文献Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
4W6W
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BU of 4w6w by Molmil
Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF6
分子名称: F18 fimbrial adhesin AC, NbFedF6
著者Moonens, K, De Kerpel, M, Annelies, C, Cox, E, Pardon, E, Remaut, H, De Greve, H.
登録日2014-08-21
公開日2014-12-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
2RK4
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BU of 2rk4 by Molmil
Structure of M26I DJ-1
分子名称: Protein DJ-1
著者Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A.
登録日2007-10-16
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1.
Biochemistry, 47, 2008
2R6T
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BU of 2r6t by Molmil
Structure of a R132K variant PduO-type ATP:co(I)rrinoid adenosyltransferase from Lactobacillus reuteri complexed with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cobalamin adenosyltransferase PduO-like protein, MAGNESIUM ION
著者St Maurice, M, Mera, P.E, Escalante-Semerena, J.C, Rayment, I.
登録日2007-09-06
公開日2007-12-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural and functional analyses of the human-type corrinoid adenosyltransferase (PduO) from Lactobacillus reuteri.
Biochemistry, 46, 2007
2RM4
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BU of 2rm4 by Molmil
Solution Structure of the LSM Domain of Dm EDC3 (Enhancer of DECAPPING 3)
分子名称: CG6311-PB
著者Truffault, V, Coles, M, Tritschler, F.
登録日2007-09-20
公開日2007-10-30
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting
Mol.Cell.Biol., 27, 2007
2RO3
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BU of 2ro3 by Molmil
RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator Abh
分子名称: Putative transition state regulator abh
著者Sullivan, D.M, Bobay, B.G, Douglas, K.J, Thompson, R.J, Rance, M, Strauch, M.A, Cavanagh, J.
登録日2008-03-08
公開日2008-11-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Insights into the nature of DNA binding of AbrB-like transcription factors
Structure, 16, 2008
4V69
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BU of 4v69 by Molmil
Ternary complex-bound E.coli 70S ribosome.
分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Villa, E, Sengupta, J, Trabuco, L.G, LeBarron, J, Baxter, W.T, Shaikh, T.R, Grassucci, R.A, Nissen, P, Ehrenberg, M, Schulten, K, Frank, J.
登録日2008-12-11
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis
Proc.Natl.Acad.Sci.USA, 106, 2009
4W6X
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BU of 4w6x by Molmil
Co-complex structure of the lectin domain of F18 fimbrial adhesin FedF with inhibitory nanobody NbFedF7
分子名称: F18 fimbrial adhesin AC, Nanobody NbFedF7
著者Moonens, K, De Kerpel, M, Coddens, A, Cox, E, Pardon, E, Remaut, H, De Greve, H.
登録日2014-08-21
公開日2014-12-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Nanobody Mediated Inhibition of Attachment of F18 Fimbriae Expressing Escherichia coli.
Plos One, 9, 2014
2RF8
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BU of 2rf8 by Molmil
Crystal Structure of the mutant C2A conjugated bile acid hydrolase from Clostridium perfringens
分子名称: Choloylglycine hydrolase, GLYCEROL
著者Rossmann, M, Saenger, W.
登録日2007-09-28
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for the catalytic activity and processing of the conjugated bile salt hydrolase from Clostridium perfringens
To be Published
2R98
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BU of 2r98 by Molmil
Crystal Structure of N-acetylglutamate synthase (selenoMet substituted) from Neisseria gonorrhoeae
分子名称: ACETYL COENZYME *A, Putative acetylglutamate synthase
著者Shi, D, Sagar, V, Jin, Z, Yu, X, Caldovic, L, Morizono, H, Allewell, N.M, Tuchman, M.
登録日2007-09-12
公開日2008-01-15
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of N-acetyl-L-glutamate synthase from Neisseria gonorrhoeae provides insights into mechanisms of catalysis and regulation.
J.Biol.Chem., 283, 2008
2R9G
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BU of 2r9g by Molmil
Crystal structure of the C-terminal fragment of AAA ATPase from Enterococcus faecium
分子名称: AAA ATPase, central region, ACETATE ION, ...
著者Ramagopal, U.A, Patskovsky, Y, Bonanno, J.B, Shi, W, Toro, R, Meyer, A.J, Rutter, M, Wu, B, Groshong, C, Gheyi, T, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-09-12
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Crystal Structure of the C-Terminal Domain of AAA ATPase from Enterococcus faecium.
To be Published
4WBA
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BU of 4wba by Molmil
Q/E mutant SA11 NSP4_CCD
分子名称: GLYCEROL, Non-structural glycoprotein NSP4, PHOSPHATE ION
著者Viskovska, M, Sastri, N.P, Hyser, J.M, Tanner, M.R, Horton, L.B, Sankaran, B, Prasad, B.V.V, Estes, M.K.
登録日2014-09-02
公開日2014-09-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Structural Plasticity of the Coiled-Coil Domain of Rotavirus NSP4.
J.Virol., 88, 2014
2RLC
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BU of 2rlc by Molmil
Crystal Structure of the Conjugated Bile Acid Hydrolase from Clostridium perfringens in Complex with Reaction Products Glycine and Cholate
分子名称: CHOLIC ACID, Choloylglycine hydrolase, GLYCINE, ...
著者Rossmann, M, Saenger, W.
登録日2007-10-18
公開日2009-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of choloyl glycine hydrolase from Clostridium perfringens
To be Published
2RLT
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BU of 2rlt by Molmil
phosphorylated CPI-17 (22-120)
分子名称: Protein phosphatase 1 regulatory subunit 14A
著者Eto, M.
登録日2007-08-11
公開日2008-07-15
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Phosphorylation-induced conformational switching of CPI-17 produces a potent myosin phosphatase inhibitor.
Structure, 15, 2007
2RM5
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BU of 2rm5 by Molmil
Glutathione peroxidase-type tryparedoxin peroxidase, oxidized form
分子名称: Glutathione peroxidase-like protein
著者Melchers, J, Feher, K, Diechtierow, M, Krauth-Siegel, L, Tews, I, Muhle-Goll, C.
登録日2007-10-03
公開日2008-07-29
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Structural basis for a distinct catalytic mechanism in Trypanosoma brucei tryparedoxin peroxidase
J.Biol.Chem., 283, 2008
2REX
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BU of 2rex by Molmil
Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase
分子名称: CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Tong, Y, Tempel, W, Shen, L, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2007-09-27
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase.
To be Published
4WB5
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BU of 4wb5 by Molmil
Crystal structure of human cAMP-dependent protein kinase A (catalytic alpha subunit)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PKI (5-24), ...
著者Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A.
登録日2014-09-02
公開日2015-01-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.641 Å)
主引用文献Structural insights into mis-regulation of protein kinase A in human tumors.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WB4
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BU of 4wb4 by Molmil
wt SA11 NSP4_CCD
分子名称: CALCIUM ION, Non-structural glycoprotein NSP4
著者Viskovska, M, Sastri, N.P, Hyser, J.M, Tanner, M.R, Horton, L.B, Sankaran, B, Prasad, B.V.V, Estes, M.K.
登録日2014-09-02
公開日2014-09-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structural Plasticity of the Coiled-Coil Domain of Rotavirus NSP4.
J.Virol., 88, 2014
2RRD
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BU of 2rrd by Molmil
Structure of HRDC domain from human Bloom syndrome protein, BLM
分子名称: HRDC domain from Bloom syndrome protein
著者Sato, A, Mishima, M, Nagai, A, Kim, S.Y, Ito, Y, Hakoshima, T, Jee, J.G, Kitano, K.
登録日2010-07-19
公開日2010-09-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the HRDC domain of human Bloom syndrome protein BLM
J.Biochem., 148, 2010
4WBH
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STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I APO - 2.2A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Protein notum homolog, ...
著者Zebisch, M, Jones, E.Y.
登録日2014-09-03
公開日2015-02-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Notum deacylates Wnt proteins to suppress signalling activity
Nature, 519, 2015

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