8SMN
| Xenopus laevis hyaluronan synthase 1, nascent HA polymer bound state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab15 heavy chain, Fab15 light chain, ... | 著者 | Gorniak, I, Zimmer, J. | 登録日 | 2023-04-26 | 公開日 | 2024-05-01 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Atomistic insights into hyaluronan synthesis, secretion, and length control To Be Published
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8SNE
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8SMP
| Xenopus laevis hyaluronan synthase 1, UDP-bound, gating loop inserted state | 分子名称: | Fab15 heavy chain, Fab15 light chain, Hyaluronan synthase 1, ... | 著者 | Gorniak, I, Zimmer, J. | 登録日 | 2023-04-26 | 公開日 | 2024-05-01 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Atomistic insights into hyaluronan synthesis, secretion, and length control To Be Published
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8T9B
| Structure of the CK variant of Fab F1 (FabC-F1) in complex with the C-terminal FN3 domain of EphA2 | 分子名称: | CK variant of Fab F1 heavy chain, CK variant of Fab F1 light chain, Ephrin type-A receptor 2 | 著者 | Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | 登録日 | 2023-06-23 | 公開日 | 2024-05-01 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Engineered Antigen-binding Fragments for Enhanced Crystallization of Antibody:Antigen Complexes To be Published
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8DJG
| ADGRL3-lectin domain in complex with an activating synthetic antibody fragment | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Isoform 2 of Adhesion G protein-coupled receptor L3, ... | 著者 | Kordon, S.P, Bandekar, S.J, Arac, D. | 登録日 | 2022-06-30 | 公開日 | 2023-02-15 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder. Nat Commun, 14, 2023
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8TS5
| Structure of the apo FabS1C_C1 | 分子名称: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | 著者 | Singer, A.U, Bruce, H.A, Blazer, L.L, Adams, J.J, Sicheri, F, Sidhu, S.S. | 登録日 | 2023-08-10 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
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8TRT
| Structure of the EphA2 CRD bound to FabS1CE_C1, monoclinic form | 分子名称: | CHLORIDE ION, Ephrin type-A receptor 2, S1CE variant of Fab C1 heavy chain, ... | 著者 | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | 登録日 | 2023-08-10 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
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8TRS
| Structure of the EphA2 CRD bound to FabS1CE_C1, trigonal form | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S. | 登録日 | 2023-08-10 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
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8DR8
| LRRC8A:C conformation 2 (oblong) top mask | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8DS9
| LRRC8A:C in MSPE3D1 nanodisc top focus | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-21 | 公開日 | 2023-03-08 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8DRO
| LRRC8A:C conformation 1 (round) LRR focus 2 | 分子名称: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562 | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-21 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8DRA
| LRRC8A:C conformation 2 (oblong) LRR mask | 分子名称: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8DRN
| LRRC8A:C conformation 1 (round) LRR focus 1 | 分子名称: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-21 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8DRE
| LRRC8A:C conformation 2 (oblong) | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8DRK
| LRRC8A:C conformation 1 (round) top focus | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-21 | 公開日 | 2023-03-08 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8DS3
| LRRC8A:C conformation 1 (round) | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-21 | 公開日 | 2023-03-08 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8DSA
| LRRC8A:C in MSP1E3D1 nanodisc | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562, Volume-regulated anion channel subunit LRRC8C | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-21 | 公開日 | 2023-03-08 | 最終更新日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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8DRQ
| LRRC8A:C conformation 1 (round) LRR focus 3 | 分子名称: | Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562 | 著者 | Kern, D.M, Brohawn, S.G. | 登録日 | 2022-07-21 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels. Nat.Struct.Mol.Biol., 30, 2023
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7JIJ
| ATP-bound AMP-activated protein kinase | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | 著者 | Yan, Y, Zhou, X.E, Powell, K, Xu, T, Brunzelle, J.S, Xu, H.X, Melcher, K. | 登録日 | 2020-07-23 | 公開日 | 2021-07-28 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (5.5 Å) | 主引用文献 | Structure of an AMPK complex in an inactive, ATP-bound state. Science, 373, 2021
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7MTB
| Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6 | 分子名称: | Fab6 heavy chain, Fab6 light chain, RETINAL, ... | 著者 | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | 登録日 | 2021-05-13 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. Nature, 595, 2021
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7MT8
| Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin | 分子名称: | RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ... | 著者 | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | 登録日 | 2021-05-13 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. Nature, 595, 2021
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7MTA
| Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab1 | 分子名称: | Fab1 Heavy chain, Fab1 Light chain, RETINAL, ... | 著者 | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | 登録日 | 2021-05-13 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. Nature, 595, 2021
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7MT9
| Rhodopsin kinase (GRK1) in complex with rhodopsin | 分子名称: | RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ... | 著者 | Chen, Q, Chen, C.-L, Tesmer, J.J.G. | 登録日 | 2021-05-13 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1. Nature, 595, 2021
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7NIU
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7NIV
| Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation) | 分子名称: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment light chain, CHOLESTEROL, ... | 著者 | Nosol, K, Locher, K.P. | 登録日 | 2021-02-14 | 公開日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures of ABCB4 provide insight into phosphatidylcholine translocation. Proc.Natl.Acad.Sci.USA, 118, 2021
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