7JIJ

ATP-bound AMP-activated protein kinase

Summary for 7JIJ

Entry DOI	10.2210/pdb7jij/pdb
Related PRD ID	PRD_900001
Descriptor	Maltose/maltodextrin ABC transporter substrate-binding protein MalE, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, ... (8 entities in total)
Functional Keywords	ampk, activation, atp-binding, signaling protein
Biological source	Escherichia coli More
Total number of polymer chains	4
Total formula weight	155813.50
Authors	Yan, Y.,Zhou, X.E.,Powell, K.,Xu, T.,Brunzelle, J.S.,Xu, H.X.,Melcher, K. (deposition date: 2020-07-23, release date: 2021-07-28, Last modification date: 2023-10-18)
Primary citation	Yan, Y.,Mukherjee, S.,Harikumar, K.G.,Strutzenberg, T.S.,Zhou, X.E.,Suino-Powell, K.,Xu, T.H.,Sheldon, R.D.,Lamp, J.,Brunzelle, J.S.,Radziwon, K.,Ellis, A.,Novick, S.J.,Vega, I.E.,Jones, R.G.,Miller, L.J.,Xu, H.E.,Griffin, P.R.,Kossiakoff, A.A.,Melcher, K. Structure of an AMPK complex in an inactive, ATP-bound state. Science, 373:413-419, 2021 Cited by PubMed: 34437114 DOI: 10.1126/science.abe7565 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (5.5 Å)

Structure validation