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1PZL
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BU of 1pzl by Molmil
Crystal structure of HNF4a LBD in complex with the ligand and the coactivator SRC-1 peptide
分子名称: Hepatocyte nuclear factor 4-alpha, MYRISTIC ACID, steroid receptor coactivator-1
著者Duda, K, Chi, Y.-I, Dhe-paganon, S, Shoelson, S.
登録日2003-07-11
公開日2004-06-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for HNF-4alpha Activation by Ligand and Coactivator Binding
J.Biol.Chem., 279, 2004
3T6J
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BU of 3t6j by Molmil
Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 3.0 Angstroms
分子名称: Dipeptidyl peptidase 3, Tynorphin
著者Bezerra, G.A, Gruber, K.
登録日2011-07-28
公開日2012-04-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.976 Å)
主引用文献Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III.
Proc.Natl.Acad.Sci.USA, 109, 2012
3T6B
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BU of 3t6b by Molmil
Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 2.4 Angstroms
分子名称: Dipeptidyl peptidase 3, Tynorphin
著者Bezerra, G.A, Gruber, K.
登録日2011-07-28
公開日2012-04-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III
Proc.Natl.Acad.Sci.USA, 109, 2012
3K9P
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BU of 3k9p by Molmil
The crystal structure of E2-25K and ubiquitin complex
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H.
登録日2009-10-16
公開日2010-09-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285, 2010
2L3R
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BU of 2l3r by Molmil
NMR structure of UHRF1 Tandem Tudor Domains in a complex with Histone H3 peptide
分子名称: E3 ubiquitin-protein ligase UHRF1, Histone H3
著者Nady, N, Lemak, A, Fares, C, Gutmanas, A, Avvakumov, G, Xue, S, Arrowsmith, C, Structural Genomics Consortium (SGC)
登録日2010-09-21
公開日2011-04-13
最終更新日2025-03-26
実験手法SOLUTION NMR
主引用文献Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein.
J.Biol.Chem., 286, 2011
6XAW
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BU of 6xaw by Molmil
Crystal Structure Analysis of SIN3-UME6
分子名称: BROMIDE ION, Transcriptional regulatory protein SIN3, Transcriptional regulatory protein UME6
著者Seo, H.-S, Dhe-Paganon, S.
登録日2020-06-04
公開日2021-06-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal Structure Analysis of SIN3-UME6
To be published
6XDJ
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BU of 6xdj by Molmil
Crystal Structure Analysis of MBP-SIN3
分子名称: Maltodextrin-binding protein,Transcriptional regulatory protein SIN3, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose
著者Seo, H.-S, Dhe-Paganon, S.
登録日2020-06-10
公開日2021-06-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure Analysis of MBP-SIN3
To be published
3PHD
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BU of 3phd by Molmil
Crystal structure of human HDAC6 in complex with ubiquitin
分子名称: Histone deacetylase 6, Polyubiquitin, ZINC ION
著者Dong, A, Qui, W, Ravichandran, M, Schuetz, A, Loppnau, P, Li, F, Mackenzie, F, Kozieradzki, I, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2010-11-03
公開日2011-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini.
J.Biol.Chem., 287, 2012
3FVY
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BU of 3fvy by Molmil
Crystal structure of human Dipeptidyl Peptidase III
分子名称: CHLORIDE ION, Dipeptidyl-peptidase 3, MAGNESIUM ION, ...
著者Dong, A, Dobrovetsky, E, Seitova, A, Duncan, B, Crombet, L, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bochkarev, A, Cossar, D, Structural Genomics Consortium (SGC)
登録日2009-01-16
公開日2009-02-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III.
Proc.Natl.Acad.Sci.USA, 109, 2012
2MF9
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BU of 2mf9 by Molmil
Solution structure of the N-terminal domain of human FKBP38 (FKBP38NTD)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP8
著者Kang, C, Ye, H, Simon, B, Sattler, M, Yoon, H.S.
登録日2013-10-08
公開日2013-11-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Functional role of the flexible N-terminal extension of FKBP38 in catalysis.
Sci Rep, 3, 2013
2PZ9
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BU of 2pz9 by Molmil
Crystal structure of putative transcriptional regulator SCO4942 from Streptomyces coelicolor
分子名称: Putative regulatory protein, SULFATE ION
著者Filippova, E.V, Chruszcz, M, Xu, X, Zheng, H, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2007-05-17
公開日2007-06-19
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献In situ proteolysis for protein crystallization and structure determination.
Nat.Methods, 4, 2007
2PVS
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BU of 2pvs by Molmil
Structure of human pancreatic lipase related protein 2 mutant N336Q
分子名称: CALCIUM ION, Pancreatic lipase-related protein 2, SULFATE ION
著者Spinelli, S, Eydoux, C, Carriere, F, Cambillau, C.
登録日2007-05-10
公開日2007-12-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation.
Biochemistry, 47, 2008
5U1M
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BU of 5u1m by Molmil
Structure of the IRS-1 PTB Domain Bound to the Juxtamembrane Region of the Insulin Receptor
分子名称: Insulin receptor, Insulin receptor substrate 1
著者Eck, M.J, Dhe-Paganon, S.
登録日2016-11-28
公開日2017-09-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression.
Nat Commun, 8, 2017
9EFX
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BU of 9efx by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with TO-584
分子名称: 4-({(cyclopentanesulfonyl)[(pyridin-3-yl)methyl]amino}methyl)-N-hydroxybenzamide, Hdac6 protein, POTASSIUM ION, ...
著者Erdogan, F, Seo, H.-S, Dhe-Paganon, S.
登録日2024-11-20
公開日2024-12-04
実験手法X-RAY DIFFRACTION (1.262 Å)
主引用文献Bisected Cap Group Modifications Provides Basis for Improved Pharmacokinetics of HDAC Inhibitors
To Be Published
9EFC
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BU of 9efc by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with TO-588
分子名称: Hdac6 protein, N-hydroxy-4-({(methanesulfonyl)[(pyridin-3-yl)methyl]amino}methyl)benzamide, POTASSIUM ION, ...
著者Erdogan, F, Seo, H.-S, Dhe-Paganon, S.
登録日2024-11-20
公開日2024-12-04
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Bisected Cap Group Modifications Provides Basis for Improved Pharmacokinetics of HDAC Inhibitors
To Be Published
9EFR
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BU of 9efr by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with TO-600
分子名称: Hdac6 protein, N-hydroxy-4-({(propane-2-sulfonyl)[(pyridin-3-yl)methyl]amino}methyl)benzamide, POTASSIUM ION, ...
著者Erdogan, F, Seo, H.-S, Dhe-Paganon, S.
登録日2024-11-20
公開日2024-12-04
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Bisected Cap Group Modifications Provides Basis for Improved Pharmacokinetics of HDAC Inhibitors
To Be Published
9EGF
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BU of 9egf by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with TO-589
分子名称: 4-({(ethanesulfonyl)[(pyridin-3-yl)methyl]amino}methyl)-N-hydroxybenzamide, Hdac6 protein, POTASSIUM ION, ...
著者Erdogan, F, Seo, H.-S, Dhe-Paganon, S.
登録日2024-11-21
公開日2024-12-04
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Bisected Cap Group Modifications Provides Basis for Improved Pharmacokinetics of HDAC Inhibitors
To Be Published
9EGU
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BU of 9egu by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with TO-599
分子名称: Hdac6 protein, N-hydroxy-4-({[(pyridin-3-yl)methyl](thiophene-3-sulfonyl)amino}methyl)benzamide, POTASSIUM ION, ...
著者Erdogan, F, Seo, H.-S, Dhe-Paganon, S.
登録日2024-11-21
公開日2024-12-04
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Bisected Cap Group Modifications Provides Basis for Improved Pharmacokinetics of HDAC Inhibitors
To Be Published
2KFV
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BU of 2kfv by Molmil
Structure of the amino-terminal domain of human FK506-binding protein 3 / Northeast Structural Genomics Consortium Target HT99A
分子名称: FK506-binding protein 3
著者Sunnerhagen, M, Davis, T, Gutmanas, A, Fares, C, Ouyang, H, Lemak, A, Li, Y, Weigelt, J, Bountra, C, Edwards, A, Arrowsmith, C.H, Dhe-Paganon, S, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC)
登録日2009-02-27
公開日2009-06-23
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structure of the N-terminal domain of FK506-binding protein 3
To be Published

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件を2025-07-09に公開中

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