3FVY

Crystal structure of human Dipeptidyl Peptidase III

Summary for 3FVY

Entry DOI	10.2210/pdb3fvy/pdb
Descriptor	Dipeptidyl-peptidase 3, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	sgc, dpp3, dipeptidyl peptidase iii, aminopeptidase, hydrolase, metal-binding, metalloprotease, phosphoprotein, protease, structural genomics, structural genomics consortium
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q9NY33
Total number of polymer chains	1
Total formula weight	81923.39
Authors	Dong, A.,Dobrovetsky, E.,Seitova, A.,Duncan, B.,Crombet, L.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bochkarev, A.,Cossar, D.,Structural Genomics Consortium (SGC) (deposition date: 2009-01-16, release date: 2009-02-03, Last modification date: 2023-09-06)
Primary citation	Bezerra, G.A.,Dobrovetsky, E.,Viertlmayr, R.,Dong, A.,Binter, A.,Abramic, M.,Macheroux, P.,Dhe-Paganon, S.,Gruber, K. Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III. Proc.Natl.Acad.Sci.USA, 109:6525-6530, 2012 Cited by PubMed: 22493238 DOI: 10.1073/pnas.1118005109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation