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3FVY

Crystal structure of human Dipeptidyl Peptidase III

Functional Information from GO Data
ChainGOidnamespacecontents
A0004177molecular_functionaminopeptidase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006508biological_processproteolysis
A0008235molecular_functionmetalloexopeptidase activity
A0008237molecular_functionmetallopeptidase activity
A0008239molecular_functiondipeptidyl-peptidase activity
A0008270molecular_functionzinc ion binding
A0030163biological_processprotein catabolic process
A0046872molecular_functionmetal ion binding
A0070062cellular_componentextracellular exosome
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ZN A1000
ChainResidue
AHIS450
AHIS455
AGLU508
AHOH874
AHOH1320

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 738
ChainResidue
AHOH924
AHOH948
AHOH830
AHOH868
AHOH899
AHOH900

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 739
ChainResidue
AGLY164
AGLY167
AHOH812
AHOH998
AHOH1230

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CL A 740
ChainResidue
AASN478
AGLN486
AHOH769
AHOH1147

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:O55096
ChainResidueDetails
AGLU451

site_idSWS_FT_FI2
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:22493238, ECO:0007744|PDB:3FVY
ChainResidueDetails
AHIS450
AHIS455
AGLU508

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: N-acetylalanine => ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378
ChainResidueDetails
AALA2

222415

PDB entries from 2024-07-10

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