5B3J
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![BU of 5b3j by Molmil](/molmil-images/mine/5b3j) | Activation of NMDA receptors and the mechanism of inhibition by ifenprodil | Descriptor: | Fab, heavy chain, light chain, ... | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | Deposit date: | 2016-03-01 | Release date: | 2016-05-11 | Last modified: | 2022-03-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Activation of NMDA receptors and the mechanism of inhibition by ifenprodil Nature, 534, 2016
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5FXG
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![BU of 5fxg by Molmil](/molmil-images/mine/5fxg) | GLUN1B-GLUN2B NMDA RECEPTOR IN ACTIVE CONFORMATION | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | Deposit date: | 2016-03-02 | Release date: | 2016-05-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016
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5FXH
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![BU of 5fxh by Molmil](/molmil-images/mine/5fxh) | GluN1b-GluN2B NMDA receptor in non-active-1 conformation | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | Deposit date: | 2016-03-02 | Release date: | 2016-05-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016
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5FXI
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![BU of 5fxi by Molmil](/molmil-images/mine/5fxi) | GluN1b-GluN2B NMDA receptor structure in non-active-2 conformation | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | Deposit date: | 2016-03-02 | Release date: | 2016-05-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.4 Å) | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016
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5FXK
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![BU of 5fxk by Molmil](/molmil-images/mine/5fxk) | GluN1b-GluN2B NMDA receptor structure-Class Y | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | Deposit date: | 2016-03-02 | Release date: | 2016-05-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.4 Å) | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016
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5FXJ
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![BU of 5fxj by Molmil](/molmil-images/mine/5fxj) | GluN1b-GluN2B NMDA receptor structure-Class X | Descriptor: | GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1, NMDA 2B | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa H, H. | Deposit date: | 2016-03-02 | Release date: | 2016-05-25 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.25 Å) | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil. Nature, 534, 2016
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7TE9
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![BU of 7te9 by Molmil](/molmil-images/mine/7te9) | |
7TE4
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![BU of 7te4 by Molmil](/molmil-images/mine/7te4) | Crystal structure of Fab2 anti-GluN2B antibody | Descriptor: | Fab anti-GluN2B antibody, heavy chain, Fab2 anti-GluN2B antibody, ... | Authors: | Tajima, N, Furukawa, H. | Deposit date: | 2022-01-04 | Release date: | 2022-03-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.456 Å) | Cite: | Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
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7TES
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![BU of 7tes by Molmil](/molmil-images/mine/7tes) | |
7TEB
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![BU of 7teb by Molmil](/molmil-images/mine/7teb) | |
7TER
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![BU of 7ter by Molmil](/molmil-images/mine/7ter) | |
7TEE
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![BU of 7tee by Molmil](/molmil-images/mine/7tee) | |
7TET
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![BU of 7tet by Molmil](/molmil-images/mine/7tet) | |
7TEQ
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![BU of 7teq by Molmil](/molmil-images/mine/7teq) | |
3AEH
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![BU of 3aeh by Molmil](/molmil-images/mine/3aeh) | |
7TE6
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![BU of 7te6 by Molmil](/molmil-images/mine/7te6) | Crystal structure of GluN1b-2B ATD complexed to Fab5 anti-GluN2B antibody | Descriptor: | Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... | Authors: | Regan, M, Tajima, N, Furukawa, H. | Deposit date: | 2022-01-04 | Release date: | 2022-03-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (4.55 Å) | Cite: | Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
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8F0O
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![BU of 8f0o by Molmil](/molmil-images/mine/8f0o) | |
8GC2
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![BU of 8gc2 by Molmil](/molmil-images/mine/8gc2) | Domoate-bound GluK2 kainate receptor in partially-open conformation 1 | Descriptor: | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bogdanovic, N, Tajima, N. | Deposit date: | 2023-03-01 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis for kainate receptor activation by a partial agonist To Be Published
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8GC5
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![BU of 8gc5 by Molmil](/molmil-images/mine/8gc5) | Domoate-bound GluK2 kainate receptors in non-active conformation | Descriptor: | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bogdanovic, N, Tajima, N. | Deposit date: | 2023-03-01 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | Structural basis for kainate receptor activation by a partial agonist To Be Published
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8GC3
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![BU of 8gc3 by Molmil](/molmil-images/mine/8gc3) | Domote-bound GluK2 kainate receptors in partially-open conformation 2 | Descriptor: | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bogdanovic, N, Tajima, N. | Deposit date: | 2023-03-01 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for kainate receptor activation by a partial agonist To Be Published
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8GC4
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![BU of 8gc4 by Molmil](/molmil-images/mine/8gc4) | Domoate-bound GluK2 kainate receptor in partially-open conformation 3 | Descriptor: | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bogdanovic, N, Tajima, N. | Deposit date: | 2023-03-01 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | Structural basis for kainate receptor activation by a partial agonist To Be Published
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4JWY
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![BU of 4jwy by Molmil](/molmil-images/mine/4jwy) | GluN2D ligand-binding core in complex with propyl-NHP5G | Descriptor: | (2R)-amino(1-hydroxy-4-propyl-1H-pyrazol-5-yl)ethanoic acid, Glutamate receptor ionotropic, NMDA 2D | Authors: | Hansen, K.B, Tajima, N, Risgaard, R, Perszyk, R.E, Jorgensen, L, Vance, K.M, Ogden, K.K, Clausen, R.P, Furukawa, H, Traynelis, S.F. | Deposit date: | 2013-03-27 | Release date: | 2013-05-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-d-aspartate receptors. Mol.Pharmacol., 84, 2013
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4JWX
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![BU of 4jwx by Molmil](/molmil-images/mine/4jwx) | GluN2A ligand-binding core in complex with propyl-NHP5G | Descriptor: | (2R)-amino(1-hydroxy-4-propyl-1H-pyrazol-5-yl)ethanoic acid, GluN2A | Authors: | Hansen, K.B, Tajima, N, Risgaard, R, Perszyk, R.E, Jorgensen, L, Vance, K.M, Ogden, K.K, Clausen, R.P, Furukawa, H, Traynelis, S.F. | Deposit date: | 2013-03-27 | Release date: | 2013-05-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-d-aspartate receptors. Mol.Pharmacol., 84, 2013
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4NF6
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![BU of 4nf6 by Molmil](/molmil-images/mine/4nf6) | Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and PPDA | Descriptor: | (2S,3R)-1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid, GLYCINE, Glutamate receptor ionotropic, ... | Authors: | Jespersen, A, Tajima, N, Furukawa, H. | Deposit date: | 2013-10-30 | Release date: | 2014-03-12 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Insights into Competitive Antagonism in NMDA Receptors. Neuron, 81, 2014
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4NF4
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![BU of 4nf4 by Molmil](/molmil-images/mine/4nf4) | Crystal structure of GluN1/GluN2A ligand-binding domain in complex with DCKA and glutamate | Descriptor: | 4-hydroxy-5,7-dimethylquinoline-2-carboxylic acid, GLUTAMIC ACID, Glutamate receptor ionotropic, ... | Authors: | Annie, J, Tajima, N, Furukawa, H. | Deposit date: | 2013-10-30 | Release date: | 2014-03-12 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Insights into Competitive Antagonism in NMDA Receptors. Neuron, 81, 2014
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