4NF4

Crystal structure of GluN1/GluN2A ligand-binding domain in complex with DCKA and glutamate

Summary for 4NF4

• Entry DOI: 10.2210/pdb4nf4/pdb
• Related: 4NF5 4NF6 4NF8
• Descriptor: Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2A, 4-hydroxy-5,7-dimethylquinoline-2-carboxylic acid, ... (5 entities in total)
• Functional Keywords: receptor, dcka and glutamate, transport protein
• Biological source: Rattus norvegicus (rat); More
• Cellular location: Cell membrane ; Multi-pass membrane protein : P35439 Q00959
• Total number of polymer chains: 2
• Total formula weight: 65489.68

Authors

Annie, J.,Tajima, N.,Furukawa, H. (deposition date: 2013-10-30, release date: 2014-03-12, Last modification date: 2017-08-09)

• Primary citation: Jespersen, A.,Tajima, N.,Fernandez-Cuervo, G.,Garnier-Amblard, E.C.,Furukawa, H.; Structural Insights into Competitive Antagonism in NMDA Receptors.; Neuron, 81:366-378, 2014; PubMed: 24462099; DOI: 10.1016/j.neuron.2013.11.033

Experimental method

X-RAY DIFFRACTION (2 Å)