4JWY

GluN2D ligand-binding core in complex with propyl-NHP5G

Summary for 4JWY

• Entry DOI: 10.2210/pdb4jwy/pdb
• Related: 4JWX
• Descriptor: Glutamate receptor ionotropic, NMDA 2D, (2R)-amino(1-hydroxy-4-propyl-1H-pyrazol-5-yl)ethanoic acid (3 entities in total)
• Functional Keywords: bilobed structure, ion channel, transport protein
• Biological source: Rattus norvegicus (brown rat,rat,rats); More
• Cellular location: Cell membrane; Multi-pass membrane protein: Q62645
• Total number of polymer chains: 1
• Total formula weight: 32270.85

Authors

Hansen, K.B.,Tajima, N.,Risgaard, R.,Perszyk, R.E.,Jorgensen, L.,Vance, K.M.,Ogden, K.K.,Clausen, R.P.,Furukawa, H.,Traynelis, S.F. (deposition date: 2013-03-27, release date: 2013-05-29, Last modification date: 2023-09-20)

• Primary citation: Hansen, K.B.,Tajima, N.,Risgaard, R.,Perszyk, R.E.,Jorgensen, L.,Vance, K.M.,Ogden, K.K.,Clausen, R.P.,Furukawa, H.,Traynelis, S.F.; Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-d-aspartate receptors.; Mol.Pharmacol., 84:114-127, 2013; PubMed: 23625947; DOI: 10.1124/mol.113.085803

Experimental method

X-RAY DIFFRACTION (2 Å)