1M2C
 
 | | THREE-DIMENSIONAL STRUCTURE OF ALPHA-CONOTOXIN MII, NMR, 14 STRUCTURES | | Descriptor: | ALPHA-CONOTOXIN MII | | Authors: | Shon, K.J, Koerber, S.C, Rivier, J.E, Olivera, B.M, Mcintosh, J.M. | | Deposit date: | 1997-09-15 | | Release date: | 1998-12-09 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors.
J.Biol.Chem., 271, 1996
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9BAF
 | | Solution NMR structure of conofurin-Delta | | Descriptor: | Alpha-conotoxin LvIA | | Authors: | Harvey, P.J, Craik, D.J, Hone, A.J, McIntosh, J.M. | | Deposit date: | 2024-04-04 | | Release date: | 2024-07-03 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Design, Synthesis, and Structure-Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus-2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors.
J.Med.Chem., 67, 2024
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5JME
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4EZ1
 | | Crystal structure of acetylcholine binding protein (AChBP) from Aplysia Californica in complex with alpha-conotoxin BuIA | | Descriptor: | Alpha-conotoxin BuIA, MANGANESE (II) ION, Soluble acetylcholine receptor | | Authors: | Talley, T.T, Reger, A.S, Kim, C, Sankaran, B, Ho, K, Taylor, P, McIntosh, J.M. | | Deposit date: | 2012-05-02 | | Release date: | 2013-05-08 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Pairwise interaction of alpha-conotoxin BuIA Pro6 with the beta subunit of nicotinic acetylcholine receptor
To be Published
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1PQR
 | | Solution Conformation of alphaA-Conotoxin EIVA | | Descriptor: | Alpha-A-conotoxin EIVA | | Authors: | Chi, S.-W, Park, K.-H, Suk, J.-E, Olivera, B.M, McIntosh, J.M, Han, K.-H. | | Deposit date: | 2003-06-18 | | Release date: | 2003-11-04 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution Conformation of alphaA-conotoxin EIVA, a Potent Neuromuscular Nicotinic Acetylcholine Receptor Antagonist from Conus ermineus
J.Biol.Chem., 278, 2003
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1UL2
 | | Solution Conformation of alpha-Conotoxin GIC | | Descriptor: | alpha-conotoxin GIC | | Authors: | Chi, S.-W, Kim, D.-H, Olivera, B.M, McIntosh, J.M, Han, K.-H. | | Deposit date: | 2003-09-06 | | Release date: | 2004-07-20 | | Last modified: | 2024-11-20 | | Method: | SOLUTION NMR | | Cite: | Solution conformation of alpha-conotoxin GIC, a novel potent antagonist of alpha3beta2 nicotinic acetylcholine receptors
Biochem.J., 380, 2004
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1ZLC
 | | Solution Conformation of alpha-conotoxin PIA | | Descriptor: | Alpha-conotoxin PIA | | Authors: | Chi, S.-W, Lee, S.-H, Kim, D.-H, Kim, J.-S, Olivera, B.M, McIntosh, J.M, Han, K.-H. | | Deposit date: | 2005-05-05 | | Release date: | 2006-05-02 | | Last modified: | 2024-10-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of alpha-conotoxin PIA, a novel antagonist of alpha6 subunit containing nicotinic acetylcholine receptors
Biochem.Biophys.Res.Commun., 338, 2005
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1K64
 | | NMR Structue of alpha-conotoxin EI | | Descriptor: | alpha-conotoxin EI | | Authors: | Park, K.H, Suk, J.E, Jacobsen, R, Gray, W.R, McIntosh, J.M, Han, K.H. | | Deposit date: | 2001-10-15 | | Release date: | 2003-09-09 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution conformation of alpha-conotoxin EI, a neuromuscular toxin specific for the alpha 1/delta subunit interface of torpedo nicotinic acetylcholine receptor
J.BIOL.CHEM., 276, 2001
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2GCZ
 | | Solution Structure of alpha-Conotoxin OmIA | | Descriptor: | Alpha-conotoxin OmIA | | Authors: | Chi, S.-W, Kim, D.-H, Olivera, B.M, McIntosh, J.M, Han, K.-H. | | Deposit date: | 2006-03-15 | | Release date: | 2006-07-25 | | Last modified: | 2024-11-20 | | Method: | SOLUTION NMR | | Cite: | Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist alpha-conotoxin OmIA that discriminates alpha3 vs. alpha6 nAChR subtypes
Biochem.Biophys.Res.Commun., 345, 2006
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2M3I
 | | Characterization of a Novel Alpha4/6-Conotoxin TxIC from Conus textile that Potently Blocks alpha3beta4 Nicotinic Acetylcholine Receptors | | Descriptor: | Alpha-conotoxin | | Authors: | Luo, S, Zhangsun, D, Zhu, X, Wu, Y, Hu, Y, Christensen, S, Akcan, M, Craik, D.J, McIntosh, J.M. | | Deposit date: | 2013-01-20 | | Release date: | 2013-12-04 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Characterization of a Novel alpha-Conotoxin TxID from Conus textile That Potently Blocks Rat alpha 3 beta 4 Nicotinic Acetylcholine Receptors.
J.Med.Chem., 56, 2013
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2I28
 | | Solution Structure of alpha-Conotoxin BuIA | | Descriptor: | Alpha-conotoxin BuIA | | Authors: | Chi, S.-W, Kim, D.-H, Olivera, B.M, McIntosh, J.M, Han, K.-H. | | Deposit date: | 2006-08-16 | | Release date: | 2006-10-31 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | NMR structure determination of alpha-conotoxin BuIA, a novel neuronal nicotinic acetylcholine receptor antagonist with an unusual 4/4 disulfide scaffold
Biochem.Biophys.Res.Commun., 349, 2006
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1DG2
 | | SOLUTION CONFORMATION OF A-CONOTOXIN AUIB | | Descriptor: | A-CONOTOXIN AUIB | | Authors: | Cho, J.-H, Mok, K.H, Olivera, B.M, McIntosh, J.M, Park, K.-H, Han, K.-H. | | Deposit date: | 1999-11-23 | | Release date: | 2000-02-25 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | Nuclear magnetic resonance solution conformation of alpha-conotoxin AuIB, an alpha(3)beta(4) subtype-selective neuronal nicotinic acetylcholine receptor antagonist.
J.Biol.Chem., 275, 2000
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9EH4
 | | Solution structure of alpha conotoxin LvID | | Descriptor: | Alpha conotoxin LvID | | Authors: | Harvey, P.J, Craik, D.J. | | Deposit date: | 2024-11-22 | | Release date: | 2025-04-23 | | Last modified: | 2025-05-07 | | Method: | SOLUTION NMR | | Cite: | Selective Inhibition of Rat alpha 7 Nicotinic Acetylcholine Receptors by LvID, a Newly Characterized alpha 4/7-Conotoxin from Conus lividus .
J.Med.Chem., 68, 2025
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1MII
 | | SOLUTION STRUCTURE OF ALPHA-CONOTOXIN MII | | Descriptor: | PROTEIN (ALPHA CONOTOXIN MII) | | Authors: | Hill, J.M, Oomen, C.J, Miranda, L.P, Bingham, J.P, Alewood, P.F, Craik, D.J. | | Deposit date: | 1998-10-05 | | Release date: | 1998-10-21 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional solution structure of alpha-conotoxin MII by NMR spectroscopy: effects of solution environment on helicity.
Biochemistry, 37, 1998
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2LZ5
 | | Solution structure of a Novel Alpha-Conotoxin TxIB | | Descriptor: | Conotoxin_TxIB | | Authors: | Luo, S, Zhangsun, D, Wu, Y, Zhu, X, Hu, Y, McIntyre, M, Christensen, S, Akcan, M, Craik, D, McIntosh, J. | | Deposit date: | 2012-09-23 | | Release date: | 2012-12-05 | | Last modified: | 2024-11-20 | | Method: | SOLUTION NMR | | Cite: | Characterization of a novel alpha-conotoxin from conus textile that selectively targets alpha6/alpha3beta2beta3 nicotinic acetylcholine receptors.
J.Biol.Chem., 288, 2013
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1OMC
 | | SOLUTION STRUCTURE OF OMEGA-CONOTOXIN GVIA USING 2-D NMR SPECTROSCOPY AND RELAXATION MATRIX ANALYSIS | | Descriptor: | OMEGA-CONOTOXIN GVIA | | Authors: | Davis, J.H, Bradley, E.K, Miljanich, G.P, Nadasdi, L, Ramachandran, J, Basus, V.J. | | Deposit date: | 1993-04-28 | | Release date: | 1994-01-31 | | Last modified: | 2025-03-26 | | Method: | SOLUTION NMR | | Cite: | Solution structure of omega-conotoxin GVIA using 2-D NMR spectroscopy and relaxation matrix analysis.
Biochemistry, 32, 1993
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1E74
 | | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R11E | | Descriptor: | ALPHA-CONOTOXIN IM1(R11E) | | Authors: | Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C. | | Deposit date: | 2000-08-24 | | Release date: | 2000-12-27 | | Last modified: | 2024-11-20 | | Method: | SOLUTION NMR | | Cite: | Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
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1E76
 | | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT D5N | | Descriptor: | ALPHA-CONOTOXIN IM1(D5N) | | Authors: | Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C. | | Deposit date: | 2000-08-24 | | Release date: | 2000-12-27 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
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1E75
 | | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R7L | | Descriptor: | ALPHA-CONOTOXIN IM1(R7L) | | Authors: | Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C. | | Deposit date: | 2000-08-24 | | Release date: | 2000-12-27 | | Last modified: | 2024-10-23 | | Method: | SOLUTION NMR | | Cite: | Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
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1IM1
 | | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1, 20 STRUCTURES | | Descriptor: | ALPHA-CONOTOXIN IM1 | | Authors: | Rogers, J.P, Luginbuhl, P, Shen, G.S, Mccabe, R.T, Stevens, R.C, Wemmer, D.E. | | Deposit date: | 1998-11-18 | | Release date: | 1999-06-15 | | Last modified: | 2024-10-23 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of alpha-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors.
Biochemistry, 38, 1999
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1G2G
 | | MINIMAL CONFORMATION OF THE ALPHA-CONOTOXIN IMI FOR THE ALPHA7 NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR RECOGNITION | | Descriptor: | ALPHA-CONOTOXIN IMI | | Authors: | Lamthanh, H, Jegou-Matheron, C, Servent, D, Menez, A, Lancelin, J.M. | | Deposit date: | 2000-10-19 | | Release date: | 2000-11-08 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Minimal conformation of the alpha-conotoxin ImI for the alpha7 neuronal nicotinic acetylcholine receptor recognition: correlated CD, NMR and binding studies.
FEBS Lett., 454, 1999
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2MDQ
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2JUS
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2JUT
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2JUR
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