2LZ5

Solution structure of a Novel Alpha-Conotoxin TxIB

Summary for 2LZ5

• Entry DOI: 10.2210/pdb2lz5/pdb
• NMR Information: BMRB: 18736
• Descriptor: Conotoxin_TxIB (1 entity in total)
• Functional Keywords: alpha-conotoxin, alpha-helix, disulfide bonds, amidated c-terminus, toxin
• Biological source: Conus textile
• Total number of polymer chains: 1
• Total formula weight: 1746.03

Authors

Luo, S.,Zhangsun, D.,Wu, Y.,Zhu, X.,Hu, Y.,McIntyre, M.,Christensen, S.,Akcan, M.,Craik, D.,McIntosh, J. (deposition date: 2012-09-23, release date: 2012-12-05, Last modification date: 2023-06-14)

• Primary citation: Luo, S.,Zhangsun, D.,Wu, Y.,Zhu, X.,Hu, Y.,McIntyre, M.,Christensen, S.,Akcan, M.,Craik, D.J.,McIntosh, J.M.; Characterization of a novel alpha-conotoxin from conus textile that selectively targets alpha6/alpha3beta2beta3 nicotinic acetylcholine receptors.; J.Biol.Chem., 288:894-902, 2013; PubMed: 23184959; DOI: 10.1074/jbc.M112.427898

Experimental method

SOLUTION NMR