Solution Structure of alpha-Conotoxin BuIA

Summary for 2I28

DescriptorAlpha-conotoxin BuIA (1 entity in total)
Functional Keywordsalpha-helix, beta-turn, two disulfide bonds, c-terminal amidation, toxin
Cellular locationSecreted P69657
Total number of polymer chains1
Total molecular weight1314.6
Chi, S.-W.,Kim, D.-H.,Olivera, B.M.,McIntosh, J.M.,Han, K.-H. (deposition date: 2006-08-16, release date: 2006-10-31, Last modification date: 2011-07-13)
Primary citation
Chi, S.-W.,Kim, D.-H.,Olivera, B.M.,McIntosh, J.M.,Han, K.-H.
NMR structure determination of alpha-conotoxin BuIA, a novel neuronal nicotinic acetylcholine receptor antagonist with an unusual 4/4 disulfide scaffold
Biochem.Biophys.Res.Commun., 349:1228-1234, 2006
PubMed: 16979596 (PDB entries with the same primary citation)
DOI: 10.1016/j.bbrc.2006.08.164
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers158.3%5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures