6WVB
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![BU of 6wvb by Molmil](/molmil-images/mine/6wvb) | Takifugu rubripes VKOR-like with warfarin | Descriptor: | S-WARFARIN, Vitamin K epoxide reductase-like protein, termini restrained by green fluorescent protein | Authors: | Liu, S, Sukumar, N, Li, W. | Deposit date: | 2020-05-05 | Release date: | 2020-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.872 Å) | Cite: | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
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6WV4
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![BU of 6wv4 by Molmil](/molmil-images/mine/6wv4) | Human VKOR C43S with warfarin | Descriptor: | S-WARFARIN, Vitamin K epoxide reductase Cys43Ser mutant, termini restrained by green fluorescent protein | Authors: | Liu, S, Sukumar, N, Li, W. | Deposit date: | 2020-05-05 | Release date: | 2020-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.012 Å) | Cite: | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
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6WV8
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![BU of 6wv8 by Molmil](/molmil-images/mine/6wv8) | Takifugu rubripes VKOR-like C138S mutant with vitamin K1 | Descriptor: | PHYLLOQUINONE, Vitamin K epoxide reductase-like protein, termini restrained by green fluorescent protein | Authors: | Liu, S, Sukumar, N, Li, W. | Deposit date: | 2020-05-05 | Release date: | 2020-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
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6WV7
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![BU of 6wv7 by Molmil](/molmil-images/mine/6wv7) | Human VKOR with Chlorophacinone | Descriptor: | Chlorophacinone, Vitamin K epoxide reductase, termini restrained by green fluorescent protein | Authors: | Liu, S, Sukumar, N, Li, W. | Deposit date: | 2020-05-05 | Release date: | 2020-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.483 Å) | Cite: | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
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6WV9
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![BU of 6wv9 by Molmil](/molmil-images/mine/6wv9) | |
6WVA
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![BU of 6wva by Molmil](/molmil-images/mine/6wva) | |
4KIK
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![BU of 4kik by Molmil](/molmil-images/mine/4kik) | Human IkB kinase beta | Descriptor: | Inhibitor of nuclear factor kappa-B kinase subunit beta, K-252A | Authors: | Liu, S, Mosyak, L. | Deposit date: | 2013-05-02 | Release date: | 2013-06-26 | Last modified: | 2013-08-28 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Crystal Structure of a Human I kappa B Kinase beta Asymmetric Dimer. J.Biol.Chem., 288, 2013
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4ZXD
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![BU of 4zxd by Molmil](/molmil-images/mine/4zxd) | Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD | Descriptor: | Hydroquinone dioxygenase large subunit, Hydroquinone dioxygenase small subunit | Authors: | Liu, S, Su, T, Zhang, C, Gu, L. | Deposit date: | 2015-05-20 | Release date: | 2015-09-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.052 Å) | Cite: | Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases. J.Biol.Chem., 290, 2015
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4ZXC
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![BU of 4zxc by Molmil](/molmil-images/mine/4zxc) | Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD in complex with Fe3+ | Descriptor: | FE (III) ION, Hydroquinone dioxygenase large subunit, Hydroquinone dioxygenase small subunit | Authors: | Liu, S, Su, T, Zhang, C, Gu, L. | Deposit date: | 2015-05-20 | Release date: | 2015-09-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases. J.Biol.Chem., 290, 2015
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4ZXA
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![BU of 4zxa by Molmil](/molmil-images/mine/4zxa) | Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD in complex with Cd2+ and 4-hydroxybenzonitrile | Descriptor: | 4-hydroxybenzonitrile, CADMIUM ION, Hydroquinone dioxygenase large subunit, ... | Authors: | Liu, S, Su, T, Zhang, C, Gu, L. | Deposit date: | 2015-05-20 | Release date: | 2015-09-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.488 Å) | Cite: | Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases. J.Biol.Chem., 290, 2015
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2LVN
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![BU of 2lvn by Molmil](/molmil-images/mine/2lvn) | Structure of the gp78 CUE domain | Descriptor: | E3 ubiquitin-protein ligase AMFR | Authors: | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | Deposit date: | 2012-07-09 | Release date: | 2012-11-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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2LVO
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![BU of 2lvo by Molmil](/molmil-images/mine/2lvo) | Structure of the gp78CUE domain bound to monubiquitin | Descriptor: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | Authors: | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | Deposit date: | 2012-07-09 | Release date: | 2012-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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2LVP
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![BU of 2lvp by Molmil](/molmil-images/mine/2lvp) | gp78CUE domain bound to the distal ubiquitin of K48-linked diubiquitin | Descriptor: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | Authors: | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | Deposit date: | 2012-07-09 | Release date: | 2012-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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6WV5
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![BU of 6wv5 by Molmil](/molmil-images/mine/6wv5) | Human VKOR C43S mutant with vitamin K1 epoxide | Descriptor: | (2R,3R)-2-hydroxy-3-methyl-2-[(2E,7S)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-2,3-dihydronaphthalene-1,4-dione, Vitamin K epoxide reductase Cys43Ser mutant, termini restrained by green fluorescent protein | Authors: | Liu, S, Sukumar, N, Li, W. | Deposit date: | 2020-05-05 | Release date: | 2020-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
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6WV6
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![BU of 6wv6 by Molmil](/molmil-images/mine/6wv6) | Human VKOR with phenindione | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Phenindione, Vitamin K epoxide reductase, ... | Authors: | Liu, S, Sukumar, N, Li, W. | Deposit date: | 2020-05-05 | Release date: | 2020-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
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6WV3
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![BU of 6wv3 by Molmil](/molmil-images/mine/6wv3) | Human VKOR with warfarin | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, S-WARFARIN, Vitamin K epoxide reductase, ... | Authors: | Liu, S, Sukumar, N, Li, W. | Deposit date: | 2020-05-05 | Release date: | 2020-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.197 Å) | Cite: | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
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6WVH
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![BU of 6wvh by Molmil](/molmil-images/mine/6wvh) | Human VKOR with Brodifacoum | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Brodifacoum, Vitamin K epoxide reductase, ... | Authors: | Liu, S, Sukumar, N, Li, W. | Deposit date: | 2020-05-06 | Release date: | 2020-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
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3TG2
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![BU of 3tg2 by Molmil](/molmil-images/mine/3tg2) | Crystal structure of the ISC domain of VibB in complex with isochorismate | Descriptor: | (5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid, TRIETHYLENE GLYCOL, Vibriobactin-specific isochorismatase | Authors: | Liu, S, Zhang, C, Niu, B, Li, N, Liu, X, Liu, M, Wei, T, Zhu, D, Huang, Y, Xu, S, Gu, L. | Deposit date: | 2011-08-17 | Release date: | 2012-08-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.101 Å) | Cite: | Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction Acta Crystallogr.,Sect.D, 68, 2012
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3TB4
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![BU of 3tb4 by Molmil](/molmil-images/mine/3tb4) | Crystal structure of the ISC domain of VibB | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Liu, S, Zhang, C, Niu, B, Li, N, Liu, M, Wei, T, Zhu, D, Xu, S, Gu, L. | Deposit date: | 2011-08-05 | Release date: | 2012-08-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction Acta Crystallogr.,Sect.D, 68, 2012
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4YHU
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![BU of 4yhu by Molmil](/molmil-images/mine/4yhu) | Yeast Prp3 C-terminal fragment 296-469 | Descriptor: | U4/U6 small nuclear ribonucleoprotein PRP3, YTTRIUM (III) ION | Authors: | Liu, S, Wahl, M.C. | Deposit date: | 2015-02-27 | Release date: | 2015-07-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing. Elife, 4, 2015
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8FN4
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![BU of 8fn4 by Molmil](/molmil-images/mine/8fn4) | Cryo-EM structure of RNase-treated RESC-A in trypanosomal RNA editing | Descriptor: | RNA-editing substrate-binding complex protein 1 (RESC1), RNA-editing substrate-binding complex protein 2 (RESC2), RNA-editing substrate-binding complex protein 3 (RESC3), ... | Authors: | Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. | Deposit date: | 2022-12-26 | Release date: | 2023-07-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing. Science, 381, 2023
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8FNC
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![BU of 8fnc by Molmil](/molmil-images/mine/8fnc) | Cryo-EM structure of RNase-treated RESC-C in trypanosomal RNA editing | Descriptor: | Mitochondrial RNA binding complex 1 subunit, Mitochondrial RNA binding protein, Phytanoyl-CoA dioxygenase family protein, ... | Authors: | Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. | Deposit date: | 2022-12-27 | Release date: | 2023-07-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing. Science, 381, 2023
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8FN6
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![BU of 8fn6 by Molmil](/molmil-images/mine/8fn6) | Cryo-EM structure of RNase-untreated RESC-A in trypanosomal RNA editing | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, RNA-editing substrate-binding complex protein 1 (RESC1), RNA-editing substrate-binding complex protein 2 (RESC2), ... | Authors: | Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. | Deposit date: | 2022-12-27 | Release date: | 2023-07-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing. Science, 381, 2023
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8FNF
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![BU of 8fnf by Molmil](/molmil-images/mine/8fnf) | Cryo-EM structure of RNase-untreated RESC-C in trypanosomal RNA editing | Descriptor: | Mitochondrial RNA binding complex 1 subunit, Mitochondrial RNA binding protein, Phytanoyl-CoA dioxygenase family protein, ... | Authors: | Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. | Deposit date: | 2022-12-27 | Release date: | 2023-07-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing. Science, 381, 2023
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8FNI
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![BU of 8fni by Molmil](/molmil-images/mine/8fni) | Cryo-EM structure of RNase-treated RESC-B in trypanosomal RNA editing | Descriptor: | RNA-editing substrate-binding complex protein 10 (RESC10), RNA-editing substrate-binding complex protein 11 (RESC11), RNA-editing substrate-binding complex protein 13 (RESC13), ... | Authors: | Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. | Deposit date: | 2022-12-27 | Release date: | 2023-07-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing. Science, 381, 2023
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