1NHH
| Crystal structure of N-terminal 40KD MutL protein (LN40) complex with ADPnP and one Rubidium | Descriptor: | 1,2-ETHANEDIOL, DNA mismatch repair protein mutL, MAGNESIUM ION, ... | Authors: | Hu, X, Machius, M, Yang, W. | Deposit date: | 2002-12-19 | Release date: | 2003-06-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Monovalent cation dependence and preference of GHKL ATPases and kinases FEBS Lett., 544, 2003
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1NHJ
| Crystal structure of N-terminal 40KD MutL/A100P mutant protein complex with ADPnP and one sodium | Descriptor: | DNA mismatch repair protein mutL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Hu, X, Machius, M, Yang, W. | Deposit date: | 2002-12-19 | Release date: | 2003-06-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Monovalent cation dependence and preference of GHKL ATPases and kinases FEBS Lett., 544, 2003
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1NHI
| Crystal structure of N-terminal 40KD MutL (LN40) complex with ADPnP and one potassium | Descriptor: | 1,2-ETHANEDIOL, DNA mismatch repair protein mutL, MAGNESIUM ION, ... | Authors: | Hu, X, Machius, M, Yang, W. | Deposit date: | 2002-12-19 | Release date: | 2003-06-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Monovalent cation dependence and preference of GHKL ATPases and kinases FEBS Lett., 544, 2003
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3B83
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3RPL
| D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase of Synechocystis sp. PCC 6803 in complex with FRUCTOSE-1,6-BISPHOSPHATE | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... | Authors: | Hu, X, Hui, D, Lingling, F, Jian, W. | Deposit date: | 2011-04-26 | Release date: | 2012-05-02 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | New insights into the structural and interactional basis for a promising route towards fructose-1,6-/sedoheptulose-1,7-bisphosphatases controlling To be Published
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3URM
| Crystal structure of the periplasmic sugar binding protein ChvE | Descriptor: | Multiple sugar-binding periplasmic receptor ChvE, beta-D-galactopyranose | Authors: | Hu, X, Zhao, J, Binns, A, Degrado, W. | Deposit date: | 2011-11-22 | Release date: | 2012-11-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Agrobacterium tumefaciens recognizes its host environment using ChvE to bind diverse plant sugars as virulence signals. Proc.Natl.Acad.Sci.USA, 110, 2013
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3UUG
| Crystal structure of the periplasmic sugar binding protein ChvE | Descriptor: | Multiple sugar-binding periplasmic receptor ChvE, beta-D-glucopyranuronic acid | Authors: | Hu, X, Zhao, J, Binns, A, Degrado, W. | Deposit date: | 2011-11-28 | Release date: | 2012-11-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Agrobacterium tumefaciens recognizes its host environment using ChvE to bind diverse plant sugars as virulence signals. Proc.Natl.Acad.Sci.USA, 110, 2013
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3LA1
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3ROJ
| D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase of Synechocystis sp. PCC 6803 | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase, ... | Authors: | Hu, X, Hui, D, Lingling, F, Jian, W. | Deposit date: | 2011-04-26 | Release date: | 2012-05-02 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | New insights into the structural and interactional basis for a promising route towards fructose-1,6-/sedoheptulose-1,7-bisphosphatases controlling To be Published
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2RBL
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2RB8
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8J1X
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8J1W
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8Y33
| A near-infrared fluorescent protein of de novo backbone design | Descriptor: | 3-[5-[(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-2-[[5-[(3-ethyl-4-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, near-infrared fluorescent protein | Authors: | Hu, X, Xu, Y. | Deposit date: | 2024-01-28 | Release date: | 2024-02-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Using Protein Design and Directed Evolution to Monomerize a Bright Near-Infrared Fluorescent Protein. Acs Synth Biol, 13, 2024
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8I8Y
| A mutant of the C-terminal complex of proteins 4.1G and NuMA | Descriptor: | Engineered protein | Authors: | Hu, X. | Deposit date: | 2023-02-06 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Combined prediction and design reveals the target recognition mechanism of an intrinsically disordered protein interaction domain. Proc.Natl.Acad.Sci.USA, 120, 2023
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8J98
| A near-infrared fluorescent protein of de novo backbone design | Descriptor: | 3-[5-[[(3~{R},4~{R})-3-ethenyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, FORMIC ACID, GLYCEROL, ... | Authors: | Hu, X, Xu, Y. | Deposit date: | 2023-05-02 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | De novo backbone design for monomerization of near-infrared fluorescent protein To Be Published
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8HDU
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8HDV
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2G6P
| Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE, COBALT (II) ION, ... | Authors: | Addlagatta, A, Hu, X, Liu, J.O, Matthews, B.W. | Deposit date: | 2006-02-24 | Release date: | 2006-06-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification of Pyridinylpyrimidines as Inhibitors of Human Methionine Aminopeptidases. Angew.Chem.Int.Ed.Engl., 45, 2006
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6U7V
| xRRM structure of spPof8 | Descriptor: | NITRATE ION, Protein pof8 | Authors: | Kim, J.-K, Hu, X, Yu, C, Jun, H.-I, Liu, J, Sankaran, B, Huang, L, Qiao, F. | Deposit date: | 2019-09-03 | Release date: | 2020-09-09 | Last modified: | 2021-03-24 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Quality-Control Mechanism for Telomerase RNA Folding in the Cell. Cell Rep, 33, 2020
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3GEX
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3I19
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8JPA
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4U7O
| Active histidine kinase bound with ATP | Descriptor: | AMP PHOSPHORAMIDATE, Histidine protein kinase sensor protein | Authors: | Cai, Y, Hu, X, Sang, J. | Deposit date: | 2014-07-31 | Release date: | 2015-09-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.395 Å) | Cite: | Conformational dynamics of the essential sensor histidine kinase WalK. Acta Crystallogr D Struct Biol, 73, 2017
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2XWT
| CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A BLOCKING TYPE TSHR AUTOANTIBODY | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, THYROID BLOCKING HUMAN AUTOANTIBODY K1-70 HEAVY CHAIN, ... | Authors: | Sanders, J, Sanders, P, Young, S, Kabelis, K, Baker, S, Sullivan, A, Evans, M, Clark, J, Wilmot, J, Hu, X, Roberts, E, Powell, M, Nunez Miguel, R, Furmaniak, J, Rees Smith, B. | Deposit date: | 2010-11-05 | Release date: | 2011-03-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of the Tsh Receptor (Tshr) Bound to a Blocking-Type Tshr Autoantibody. J.Mol.Endocrinol., 46, 2011
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