8Y33

A near-infrared fluorescent protein of de novo backbone design

Summary for 8Y33

Entry DOI	10.2210/pdb8y33/pdb
Descriptor	near-infrared fluorescent protein, 3-[5-[(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-2-[[5-[(3-ethyl-4-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid (2 entities in total)
Functional Keywords	de novo backbone design, monomerization, near-infrared fluorescent protein, de novo protein
Biological source	synthetic construct
Total number of polymer chains	1
Total formula weight	21723.38
Authors	Hu, X.,Xu, Y. (deposition date: 2024-01-28, release date: 2024-02-28, Last modification date: 2024-04-17)
Primary citation	Hu, X.,Xu, Y.,Yi, J.,Wang, C.,Zhu, Z.,Yue, T.,Zhang, H.,Wang, X.,Wu, F.,Xue, L.,Bai, L.,Liu, H.,Chen, Q. Using Protein Design and Directed Evolution to Monomerize a Bright Near-Infrared Fluorescent Protein. Acs Synth Biol, 2024 Cited by PubMed: 38552148 DOI: 10.1021/acssynbio.3c00643 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation