2G6P
Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative
Summary for 2G6P
| Entry DOI | 10.2210/pdb2g6p/pdb |
| Related | 2B3H |
| Descriptor | Methionine aminopeptidase 1, COBALT (II) ION, POTASSIUM ION, ... (7 entities in total) |
| Functional Keywords | hydrolase, methionine aminopeptidase, pyridinyl pyrimidine |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 35050.01 |
| Authors | Addlagatta, A.,Hu, X.,Liu, J.O.,Matthews, B.W. (deposition date: 2006-02-24, release date: 2006-06-20, Last modification date: 2024-02-14) |
| Primary citation | Hu, X.,Addlagatta, A.,Matthews, B.W.,Liu, J.O. Identification of Pyridinylpyrimidines as Inhibitors of Human Methionine Aminopeptidases. Angew.Chem.Int.Ed.Engl., 45:3772-3775, 2006 Cited by PubMed: 16724298DOI: 10.1002/anie.200600757 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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