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2G6P

Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with Pyridyl pyrimidine derivative

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Methionine aminopeptidase 1polymer30434178.91UniProt (P53582)
Pfam (PF00557)
Homo sapiens (human)MetAP 1, MAP 1, Peptidase M 1
2B, C, D
(A)
COBALT (II) IONnon-polymer58.93Chemie (CO)
3E
(A)
POTASSIUM IONnon-polymer39.11Chemie (K)
4F
(A)
5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINEnon-polymer324.81Chemie (HM2)
5G
(A)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
6H
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
7I
(A)
waterwater18.0179Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34178.9
Non-Polymers*Number of molecules7
Total formula weight871.1
All*Total formula weight35050.0
*Water molecules are not included.

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PDB entries from 2025-12-24

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