4QXR
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![BU of 4qxr by Molmil](/molmil-images/mine/4qxr) | Crystal structure of hSTING(S162A/G230I/Q266I) in complex with DMXAA | Descriptor: | (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, SULFATE ION, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2014-07-21 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA. Cell Rep, 8, 2014
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4QXQ
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![BU of 4qxq by Molmil](/molmil-images/mine/4qxq) | Crystal structure of hSTING(S162A/Q266I) in complex with DMXAA | Descriptor: | (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, SULFATE ION, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2014-07-21 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA. Cell Rep, 8, 2014
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4QXO
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![BU of 4qxo by Molmil](/molmil-images/mine/4qxo) | Crystal structure of hSTING(group2) in complex with DMXAA | Descriptor: | (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2014-07-21 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA. Cell Rep, 8, 2014
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4QXP
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![BU of 4qxp by Molmil](/molmil-images/mine/4qxp) | Crystal structure of hSTING(G230I) in complex with DMXAA | Descriptor: | (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2014-07-21 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA. Cell Rep, 8, 2014
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5KK5
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![BU of 5kk5 by Molmil](/molmil-images/mine/5kk5) | AsCpf1(E993A)-crRNA-DNA ternary complex | Descriptor: | CRISPR-associated endonuclease Cpf1, DNA (28-MER), DNA (8-mer), ... | Authors: | Gao, P, Yang, H, Rajashankar, K.R, Huang, Z, Patel, D.J. | Deposit date: | 2016-06-21 | Release date: | 2016-08-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.289 Å) | Cite: | Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition. Cell Res., 26, 2016
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4LOL
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![BU of 4lol by Molmil](/molmil-images/mine/4lol) | Crystal structure of mSting in complex with DMXAA | Descriptor: | (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOI
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![BU of 4loi by Molmil](/molmil-images/mine/4loi) | Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(2',5')p] | Descriptor: | 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one, PHOSPHATE ION, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOK
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![BU of 4lok by Molmil](/molmil-images/mine/4lok) | Crystal structure of mSting in complex with c[G(3',5')pA(3',5')p] | Descriptor: | 2-amino-9-[(2R,3R,3aR,5S,7aS,9R,10R,10aR,12R,14aS)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOH
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![BU of 4loh by Molmil](/molmil-images/mine/4loh) | Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(3',5')p] | Descriptor: | Stimulator of interferon genes protein, cGAMP | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOJ
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![BU of 4loj by Molmil](/molmil-images/mine/4loj) | Crystal structure of mSting in complex with c[G(2',5')pA(3',5')p] | Descriptor: | Stimulator of interferon genes protein, cGAMP | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4K96
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![BU of 4k96 by Molmil](/molmil-images/mine/4k96) | Structure of Binary Complex of cGAS with Bound dsDNA | Descriptor: | Cyclic GMP-AMP synthase, DNA-F, DNA-R, ... | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.084 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4K98
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![BU of 4k98 by Molmil](/molmil-images/mine/4k98) | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | Descriptor: | Cyclic GMP-AMP synthase, DNA-F, DNA-R, ... | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4K8V
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![BU of 4k8v by Molmil](/molmil-images/mine/4k8v) | Structure of cyclic GMP-AMP Synthase (cGAS) | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-18 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4K99
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![BU of 4k99 by Molmil](/molmil-images/mine/4k99) | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppdG(2 ,5 )pdG | Descriptor: | 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 3'-deoxy-guanosine 5'-monophosphate, Cyclic GMP-AMP synthase, ... | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4K97
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![BU of 4k97 by Molmil](/molmil-images/mine/4k97) | Structure of Ternary Complex of cGAS with dsDNA and Bound ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ... | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4K9B
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![BU of 4k9b by Molmil](/molmil-images/mine/4k9b) | Structure of Ternary Complex of cGAS with dsDNA and Bound c[G(2 ,5 )pA(3 ,5 )p] | Descriptor: | ADENOSINE MONOPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ... | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4K9A
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![BU of 4k9a by Molmil](/molmil-images/mine/4k9a) | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pG(2 ,5 )pA | Descriptor: | ADENOSINE MONOPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ... | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.264 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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8XH7
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![BU of 8xh7 by Molmil](/molmil-images/mine/8xh7) | Structure of EBV LMP1 oligomer | Descriptor: | Latent membrane protein 1 | Authors: | Gao, P, Huang, J.F. | Deposit date: | 2023-12-17 | Release date: | 2024-06-26 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Assembly and activation of EBV latent membrane protein 1. Cell, 2024
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8XH6
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![BU of 8xh6 by Molmil](/molmil-images/mine/8xh6) | Structure of EBV LMP1 dimer | Descriptor: | Latent membrane protein 1 | Authors: | Gao, P, Huang, J.F. | Deposit date: | 2023-12-17 | Release date: | 2024-06-26 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Assembly and activation of EBV latent membrane protein 1. Cell, 2024
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7BXF
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![BU of 7bxf by Molmil](/molmil-images/mine/7bxf) | MvcA-Lpg2149 complex | Descriptor: | Lpg2149, MvcA, PRASEODYMIUM ION | Authors: | Gao, P. | Deposit date: | 2020-04-19 | Release date: | 2020-05-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. Nat Commun, 11, 2020
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7BXG
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![BU of 7bxg by Molmil](/molmil-images/mine/7bxg) | MavC-UBE2N-Ub complex | Descriptor: | MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N | Authors: | Gao, P, Wang, Y. | Deposit date: | 2020-04-19 | Release date: | 2020-05-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.705 Å) | Cite: | Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. Nat Commun, 11, 2020
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7BXH
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![BU of 7bxh by Molmil](/molmil-images/mine/7bxh) | MavC-Lpg2149 complex | Descriptor: | Lpg2149, MavC | Authors: | Gao, P, Wang, Y. | Deposit date: | 2020-04-19 | Release date: | 2020-05-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. Nat Commun, 11, 2020
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3OKG
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![BU of 3okg by Molmil](/molmil-images/mine/3okg) | Crystal structure of HsdS subunit from Thermoanaerobacter tengcongensis | Descriptor: | Restriction endonuclease S subunits, SULFATE ION | Authors: | Liang, D, Gao, P, Tang, Q, An, X, Yan, X. | Deposit date: | 2010-08-24 | Release date: | 2011-05-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of HsdS subunit from Thermoanaerobacter tengcongensis sheds lights on mechanism of dynamic opening and closing of type I methyltransferase Plos One, 6, 2011
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7BYF
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![BU of 7byf by Molmil](/molmil-images/mine/7byf) | The crystal structure of mouse ORF10-Rae1-Nup98 complex | Descriptor: | 10 protein, MERCURY (II) ION, Peptidase S59 domain-containing protein, ... | Authors: | Gao, P, Feng, H. | Deposit date: | 2020-04-22 | Release date: | 2021-03-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10. Proc.Natl.Acad.Sci.USA, 117, 2020
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4HRH
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![BU of 4hrh by Molmil](/molmil-images/mine/4hrh) | Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide | Descriptor: | Helicase-like transcription factor, Protein S100-A10, Annexin A2, ... | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2012-10-27 | Release date: | 2013-03-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.001 Å) | Cite: | SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action. Cell(Cambridge,Mass.), 152, 2013
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