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6DMS
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BU of 6dms by Molmil
Endo-fucoidan hydrolase MfFcnA4_H294Q from glycoside hydrolase family 107
Descriptor: 1,2-ETHANEDIOL, Alpha-1,4-endofucoidanase, CALCIUM ION
Authors:Vickers, C, Abe, K, Salama-Alber, O, Boraston, A.B.
Deposit date:2018-06-05
Release date:2018-10-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Endo-fucoidan hydrolases from glycoside hydrolase family 107 (GH107) display structural and mechanistic similarities to alpha-l-fucosidases from GH29.
J. Biol. Chem., 293, 2018
6DLH
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BU of 6dlh by Molmil
Endo-fucoidan hydrolase MfFcnA4 from glycoside hydrolase family 107
Descriptor: 1,2-ETHANEDIOL, Alpha-1,4-endofucoidanase, CALCIUM ION, ...
Authors:Vickers, C, Abe, K, Salama-Alber, O, Boraston, A.B.
Deposit date:2018-06-01
Release date:2018-10-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Endo-fucoidan hydrolases from glycoside hydrolase family 107 (GH107) display structural and mechanistic similarities to alpha-l-fucosidases from GH29.
J. Biol. Chem., 293, 2018
4X6L
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BU of 4x6l by Molmil
Crystal structure of S. aureus TarM in complex with UDP
Descriptor: TarM, URIDINE-5'-DIPHOSPHATE
Authors:Worrall, L.J, Sobhanifar, S, Gruninger, R.J, Strynadka, N.C.
Deposit date:2014-12-08
Release date:2015-02-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X7P
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BU of 4x7p by Molmil
Crystal structure of apo S. aureus TarM
Descriptor: SULFATE ION, TarM
Authors:Worrall, L.J, Sobhanifar, S, Gruninger, R.J, Strynadka, N.C.
Deposit date:2014-12-09
Release date:2015-02-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X7M
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BU of 4x7m by Molmil
Crystal structure of S. aureus TarM G117R mutant in complex with UDP and UDP-GlcNAc
Descriptor: TarM, URIDINE-5'-DIPHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Worrall, L.J, Sobhanifar, S, Strynadka, N.C.
Deposit date:2014-12-09
Release date:2015-03-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X7R
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BU of 4x7r by Molmil
Crystal structure of S. aureus TarM G117R mutant in complex with Fondaparinux, alpha-GlcNAc-glycerol and UDP
Descriptor: (2S)-2,3-dihydroxypropyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, TarM, ...
Authors:Worrall, L.J, Sobhanifar, S, Strynadka, N.C.
Deposit date:2014-12-09
Release date:2015-02-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X0N
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BU of 4x0n by Molmil
Porcine pancreatic alpha-amylase in complex with helianthamide, a novel proteinaceous inhibitor
Descriptor: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Williams, L.K, Brayer, G.D.
Deposit date:2014-11-21
Release date:2015-11-25
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.6001 Å)
Cite:Structural Templating and Guided Refolding of the Potent Naturally Occurring Peptide Helianthamide Within the Active Site of Amylase, a Diabetes and Obesity Therapeutic Target
To Be Published
4GPB
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BU of 4gpb by Molmil
COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor: 2-deoxy-2-fluoro-1-O-phosphono-alpha-D-glucopyranose, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE
Authors:Martin, J.L, Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
4GQR
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BU of 4gqr by Molmil
Human Pancreatic alpha-amylase in complex with myricetin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, CALCIUM ION, ...
Authors:Williams, L.K, Brayer, G.D.
Deposit date:2012-08-23
Release date:2012-10-24
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Order and disorder: differential structural impacts of myricetin and ethyl caffeate on human amylase, an antidiabetic target.
J.Med.Chem., 55, 2012
4GQQ
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BU of 4gqq by Molmil
Human pancreatic alpha-amylase with bound ethyl caffeate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Williams, L.K, Brayer, G.D.
Deposit date:2012-08-23
Release date:2012-10-24
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Order and disorder: differential structural impacts of myricetin and ethyl caffeate on human amylase, an antidiabetic target.
J.Med.Chem., 55, 2012
6DNS
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BU of 6dns by Molmil
Endo-fucoidan hydrolase MfFcnA9 from glycoside hydrolase family 107
Descriptor: 1,2-ETHANEDIOL, Alpha-1,4-endofucoidanase, CALCIUM ION
Authors:Vickers, C, Abe, K, Salama-Alber, O, Boraston, A.B.
Deposit date:2018-06-07
Release date:2018-10-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Endo-fucoidan hydrolases from glycoside hydrolase family 107 (GH107) display structural and mechanistic similarities to alpha-l-fucosidases from GH29.
J. Biol. Chem., 293, 2018
5BO8
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BU of 5bo8 by Molmil
Structure of human sialyltransferase ST8SiaIII
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ...
Authors:Volkers, G, Worrall, L, Strynadka, N.C.J.
Deposit date:2015-05-27
Release date:2015-07-15
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation.
Nat.Struct.Mol.Biol., 22, 2015
1U8X
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BU of 1u8x by Molmil
CRYSTAL STRUCTURE OF GLVA FROM BACILLUS SUBTILIS, A METAL-REQUIRING, NAD-DEPENDENT 6-PHOSPHO-ALPHA-GLUCOSIDASE
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, MANGANESE (II) ION, Maltose-6'-phosphate glucosidase, ...
Authors:Rajan, S.S, Yang, X, Collart, F, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-08-09
Release date:2004-08-24
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Novel Catalytic Mechanism of Glycoside Hydrolysis Based on the Structure of an NAD(+)/Mn(2+)-Dependent Phospho-alpha-Glucosidase from Bacillus subtilis.
STRUCTURE, 12, 2004
7GPB
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BU of 7gpb by Molmil
STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
Descriptor: ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Barford, D, Hu, S.-H, Johnson, L.N.
Deposit date:1990-11-13
Release date:1992-10-15
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
8GPB
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BU of 8gpb by Molmil
STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
Descriptor: ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE
Authors:Barford, D, Hu, S.-H, Johnson, L.N.
Deposit date:1990-11-13
Release date:1992-10-15
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
6GPB
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BU of 6gpb by Molmil
REFINED CRYSTAL STRUCTURE OF THE PHOSPHORYLASE-HEPTULOSE 2-PHOSPHATE-OLIGOSACCHARIDE-AMP COMPLEX
Descriptor: 1-deoxy-2-O-phosphono-alpha-D-gluco-hept-2-ulopyranose, ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, ...
Authors:Acharya, K.R, Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Refined crystal structure of the phosphorylase-heptulose 2-phosphate-oligosaccharide-AMP complex.
J.Mol.Biol., 211, 1990
3GPB
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BU of 3gpb by Molmil
COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor: 1-O-phosphono-alpha-D-glucopyranose, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE
Authors:Martin, J.L, Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
4C4C
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BU of 4c4c by Molmil
Michaelis complex of Hypocrea jecorina CEL7A E217Q mutant with cellononaose spanning the active site
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLULOSE 1,4-BETA-CELLOBIOSIDASE, COBALT (II) ION, ...
Authors:Haddad-Momeni, M, Sandgren, M, Stahlberg, J.
Deposit date:2013-09-05
Release date:2014-01-08
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Mechanism of Cellulose Hydrolysis by a Two-Step, Retaining Cellobiohydrolase Elucidated by Structural and Transition Path Sampling Studies.
J.Am.Chem.Soc., 136, 2014
6M8N
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BU of 6m8n by Molmil
Endo-fucoidan hydrolase P5AFcnA from glycoside hydrolase family 107
Descriptor: CALCIUM ION, MALONATE ION, P5AFcnA
Authors:Boraston, A.B, Vickers, C.J, Abe, K, Salama-Alber, O.
Deposit date:2018-08-22
Release date:2018-10-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Endo-fucoidan hydrolases from glycoside hydrolase family 107 (GH107) display structural and mechanistic similarities to alpha-l-fucosidases from GH29.
J. Biol. Chem., 293, 2018
2A75
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BU of 2a75 by Molmil
Trypanosoma rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)
Descriptor: 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, SULFATE ION, sialidase
Authors:Amaya, M.F, Alzari, P.M, Buschiazzo, A.
Deposit date:2005-07-04
Release date:2005-11-22
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase.
J.Biol.Chem., 281, 2006
5FCZ
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BU of 5fcz by Molmil
Streptomyces plicatus N-acetyl-beta-hexosaminidase in complex with Thio-NAglucal (TNX)
Descriptor: 1,5-anhydro-2-deoxy-2-(ethanethioylamino)-D-arabino-hex-1-enitol, B-N-acetylhexosaminidase, CHLORIDE ION, ...
Authors:Vadlamani, G, Mark, B.L.
Deposit date:2015-12-15
Release date:2016-10-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases.
Chem.Commun.(Camb.), 52, 2016
5KEZ
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BU of 5kez by Molmil
Selective and potent inhibition of the glycosidase human amylase by the short and extremely compact peptide piHA from mRNA display
Descriptor: ACE-DTY-PRO-TYR-SER-CYS-TRP-VAL-ARG-HIS-NH2, CALCIUM ION, CHLORIDE ION, ...
Authors:Caner, S, Brayer, G.D.
Deposit date:2016-06-10
Release date:2017-03-29
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Rapid Discovery of Potent and Selective Glycosidase-Inhibiting De Novo Peptides.
Cell Chem Biol, 24, 2017
8TDH
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BU of 8tdh by Molmil
Structure of trehalose bound Alistipes sp. Glucoside-3-dehydrogenase AL3
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Predicted dehydrogenases and related proteins, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose
Authors:Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2023-07-03
Release date:2024-06-19
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
8TDE
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BU of 8tde by Molmil
Structure of glucose bound Bacteroides thetaiotaomicron 3-Keto-2-hydroxy-glucal-hydratase BT2
Descriptor: POTASSIUM ION, Probable secreted glycosyl hydrolase, alpha-D-glucopyranose
Authors:Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2023-07-02
Release date:2024-06-12
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024
8TDA
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BU of 8tda by Molmil
Structure of Bacteroides thetaiotaomicron 3-Keto-2-hydroxy-glucal-hydratase BT2
Descriptor: POTASSIUM ION, Probable secreted glycosyl hydrolase
Authors:Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2023-07-02
Release date:2024-06-12
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:An alternative broad-specificity pathway for glycan breakdown in bacteria.
Nature, 631, 2024

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