4X7R

Crystal structure of S. aureus TarM G117R mutant in complex with Fondaparinux, alpha-GlcNAc-glycerol and UDP

Summary for 4X7R

• Entry DOI: 10.2210/pdb4x7r/pdb
• Related: 4X6L 4X7M 4X7P
• Related PRD ID: PRD_900028
• Descriptor: TarM, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, URIDINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: glycosyltransferase gt-b retaining wall teichoic acid, transferase
• Biological source: Staphylococcus aureus subsp. aureus 21178
• Total number of polymer chains: 2
• Total formula weight: 119343.09

Authors

Worrall, L.J.,Sobhanifar, S.,Strynadka, N.C. (deposition date: 2014-12-09, release date: 2015-02-25, Last modification date: 2024-02-28)

• Primary citation: Sobhanifar, S.,Worrall, L.J.,Gruninger, R.J.,Wasney, G.A.,Blaukopf, M.,Baumann, L.,Lameignere, E.,Solomonson, M.,Brown, E.D.,Withers, S.G.,Strynadka, N.C.; Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.; Proc.Natl.Acad.Sci.USA, 112:E576-E585, 2015; PubMed: 25624472; DOI: 10.1073/pnas.1418084112

Experimental method

X-RAY DIFFRACTION (2.15 Å)