5BO8

Structure of human sialyltransferase ST8SiaIII

Summary for 5BO8

Entry DOI	10.2210/pdb5bo8/pdb
Related	5BO6 5BO7 5BO9
Descriptor	Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	sialyltransferase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	84271.77
Authors	Volkers, G.,Worrall, L.,Strynadka, N.C.J. (deposition date: 2015-05-27, release date: 2015-07-15, Last modification date: 2023-09-27)
Primary citation	Volkers, G.,Worrall, L.J.,Kwan, D.H.,Yu, C.C.,Baumann, L.,Lameignere, E.,Wasney, G.A.,Scott, N.E.,Wakarchuk, W.,Foster, L.J.,Withers, S.G.,Strynadka, N.C. Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation. Nat.Struct.Mol.Biol., 22:627-635, 2015 Cited by PubMed: 26192331 DOI: 10.1038/nsmb.3060 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation