5FCZ
Streptomyces plicatus N-acetyl-beta-hexosaminidase in complex with Thio-NAglucal (TNX)
Summary for 5FCZ
| Entry DOI | 10.2210/pdb5fcz/pdb |
| Related | 1HP4 1HP5 1JAK 1M01 5FD0 |
| Descriptor | B-N-acetylhexosaminidase, 1,5-anhydro-2-deoxy-2-(ethanethioylamino)-D-arabino-hex-1-enitol, SULFATE ION, ... (6 entities in total) |
| Functional Keywords | family 20 glycoside hydrolase, sphex, gh20, thio-nag-glucal, hexosaminidase, glycosidase inhibitor, hydrolase |
| Biological source | Streptomyces plicatus |
| Total number of polymer chains | 1 |
| Total formula weight | 56913.88 |
| Authors | Vadlamani, G.,Mark, B.L. (deposition date: 2015-12-15, release date: 2016-10-26, Last modification date: 2023-09-27) |
| Primary citation | Santana, A.G.,Vadlamani, G.,Mark, B.L.,Withers, S.G. N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases. Chem.Commun.(Camb.), 52:7943-7946, 2016 Cited by PubMed: 27253678DOI: 10.1039/c6cc02520j PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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