5YC0
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![BU of 5yc0 by Molmil](/molmil-images/mine/5yc0) | Crystal structure of LP-46/N44 | Descriptor: | Envelope glycoprotein, LP-46 | Authors: | Zhang, X, Wang, X, He, Y. | Deposit date: | 2017-09-05 | Release date: | 2018-02-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Exceptional potency and structural basis of a T1249-derived lipopeptide fusion inhibitor against HIV-1, HIV-2, and simian immunodeficiency virus J. Biol. Chem., 293, 2018
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6X19
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![BU of 6x19 by Molmil](/molmil-images/mine/6x19) | Non peptide agonist CHU-128, bound to Glucagon-Like peptide-1 (GLP-1) Receptor | Descriptor: | 3-{(1S)-1-[5-(2,2-dimethylmorpholin-4-yl)-2-{(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carbonyl}-1H-indol-1-yl]butyl}-1,2,4-oxadiazol-5(4H)-one, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Belousoff, M.J, Zhang, X, Danev, R. | Deposit date: | 2020-05-18 | Release date: | 2020-09-09 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol.Cell, 80, 2020
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6X18
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![BU of 6x18 by Molmil](/molmil-images/mine/6x18) | GLP-1 peptide hormone bound to Glucagon-Like peptide-1 (GLP-1) Receptor | Descriptor: | Glucagon, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Belousoff, M.J, Zhang, X, Danev, R. | Deposit date: | 2020-05-18 | Release date: | 2020-09-09 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol.Cell, 80, 2020
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5Y9W
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![BU of 5y9w by Molmil](/molmil-images/mine/5y9w) | Crystal 1 for AtLURE1.2-AtPRK6LRR | Descriptor: | Pollen receptor-like kinase 6, Protein LURE 1.2, SULFATE ION | Authors: | Chai, J, Zhang, X. | Deposit date: | 2017-08-28 | Release date: | 2017-12-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.847 Å) | Cite: | Structural basis for receptor recognition of pollen tube attraction peptides. Nat Commun, 8, 2017
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5YAH
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![BU of 5yah by Molmil](/molmil-images/mine/5yah) | Crystal 2 for AtLURE1.2-AtPRK6LRR | Descriptor: | Pollen receptor-like kinase 6, Protein LURE 1.2 | Authors: | Chai, J, Zhang, X. | Deposit date: | 2017-08-31 | Release date: | 2018-04-11 | Method: | X-RAY DIFFRACTION (2.104 Å) | Cite: | Structural basis for receptor recognition of pollen tube attraction peptides. Nat Commun, 8, 2017
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8XJK
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![BU of 8xjk by Molmil](/molmil-images/mine/8xjk) | Cloprosetnol bound Prostaglandin F2-alpha receptor-Gq Protein Complex | Descriptor: | (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | Authors: | Zhang, X, Li, X, Liu, G, Gong, W. | Deposit date: | 2023-12-21 | Release date: | 2024-02-28 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.63 Å) | Cite: | Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Rep, 43, 2024
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8XJO
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![BU of 8xjo by Molmil](/molmil-images/mine/8xjo) | U46619 bound Thromboxane A2 receptor-Gq Protein Complex | Descriptor: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | Authors: | Zhang, X, Li, X, Liu, G, Gong, W. | Deposit date: | 2023-12-21 | Release date: | 2024-02-28 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Rep, 43, 2024
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8XJN
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![BU of 8xjn by Molmil](/molmil-images/mine/8xjn) | Cloprosetnol bound Thromboxane A2 receptor-Gq Protein Complex | Descriptor: | (~{Z})-7-[(1~{R},2~{R},3~{R},5~{S})-2-[(~{E},3~{R})-4-(3-chloranylphenoxy)-3-oxidanyl-but-1-enyl]-3,5-bis(oxidanyl)cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | Authors: | Zhang, X, Li, X, Liu, G, Gong, W. | Deposit date: | 2023-12-21 | Release date: | 2024-02-28 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Rep, 43, 2024
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8XJL
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![BU of 8xjl by Molmil](/molmil-images/mine/8xjl) | PGF2-alpha bound Prostaglandin F2-alpha receptor-Gq Protein Complex | Descriptor: | (Z)-7-[(1R,2R,3R,5S)-3,5-bis(oxidanyl)-2-[(E,3S)-3-oxidanyloct-1-enyl]cyclopentyl]hept-5-enoic acid, Antibody fragment scFv16, Engineered miniGq, ... | Authors: | Zhang, X, Li, X, Liu, G, Gong, W. | Deposit date: | 2023-12-21 | Release date: | 2024-02-28 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Rep, 43, 2024
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8XJM
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![BU of 8xjm by Molmil](/molmil-images/mine/8xjm) | Latanoprost acid bound Prostaglandin F2-alpha receptor-Gq Protein Complex | Descriptor: | Antibody fragment scFv16, Engineered miniGq, Fusion tag,Prostaglandin F2-alpha receptor,LgBiT, ... | Authors: | Zhang, X, Li, X, Liu, G, Gong, W. | Deposit date: | 2023-12-21 | Release date: | 2024-02-28 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural basis for ligand recognition and activation of the prostanoid receptors. Cell Rep, 43, 2024
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5XWY
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![BU of 5xwy by Molmil](/molmil-images/mine/5xwy) | Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex | Descriptor: | A type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, Cas13a, RNA (59-MER) | Authors: | Zhang, X, Wang, Y, Ma, J, Liu, L, Li, X, Li, Z, You, L, Wang, J, Wang, M. | Deposit date: | 2017-06-30 | Release date: | 2017-09-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a. Cell, 170, 2017
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4RSQ
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![BU of 4rsq by Molmil](/molmil-images/mine/4rsq) | 2.9A resolution structure of SRPN2 (K198C/E359C) from Anopheles gambiae | Descriptor: | Serpin 2 | Authors: | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | Deposit date: | 2014-11-10 | Release date: | 2014-12-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290, 2015
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4ROA
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![BU of 4roa by Molmil](/molmil-images/mine/4roa) | 1.90A resolution structure of SRPN2 (S358W) from Anopheles gambiae | Descriptor: | Serpin 2 | Authors: | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | Deposit date: | 2014-10-28 | Release date: | 2014-12-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290, 2015
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5ZKZ
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![BU of 5zkz by Molmil](/molmil-images/mine/5zkz) | |
5ZIW
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![BU of 5ziw by Molmil](/molmil-images/mine/5ziw) | |
4ROB
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![BU of 4rob by Molmil](/molmil-images/mine/4rob) | 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae | Descriptor: | Serpin 2 | Authors: | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | Deposit date: | 2014-10-28 | Release date: | 2014-12-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | 2.8A resolution structure of SRPN2 (K198C) from Anopheles gambiae To be Published
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4RO9
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![BU of 4ro9 by Molmil](/molmil-images/mine/4ro9) | 2.0A resolution structure of SRPN2 (S358E) from Anopheles gambiae | Descriptor: | GLYCEROL, Serpin 2 | Authors: | Lovell, S, Battaile, K.P, Zhang, X, Meekins, D.A, An, C, Michel, K. | Deposit date: | 2014-10-28 | Release date: | 2014-12-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290, 2015
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5XUR
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![BU of 5xur by Molmil](/molmil-images/mine/5xur) | Crystal Structure of Rv2466c C22S Mutant | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Thioredoxin-like reductase Rv2466c | Authors: | Zhang, X, Li, H. | Deposit date: | 2017-06-25 | Release date: | 2018-03-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.996 Å) | Cite: | Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis. ACS Infect Dis, 4, 2018
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2Z41
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![BU of 2z41 by Molmil](/molmil-images/mine/2z41) | Crystal Structure Analysis of the Ski2-type RNA helicase | Descriptor: | MAGNESIUM ION, putative ski2-type helicase | Authors: | Nakashima, T, Zhang, X, Kakuta, Y, Yao, M, Tanaka, I, Kimura, M. | Deposit date: | 2007-06-12 | Release date: | 2008-04-08 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.51 Å) | Cite: | Crystal structure of an archaeal Ski2p-like protein from Pyrococcus horikoshii OT3 Protein Sci., 17, 2008
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6X1A
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![BU of 6x1a by Molmil](/molmil-images/mine/6x1a) | Non peptide agonist PF-06882961, bound to Glucagon-Like peptide-1 (GLP-1) Receptor | Descriptor: | 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Belousoff, M.J, Zhang, X, Danev, R. | Deposit date: | 2020-05-18 | Release date: | 2020-09-09 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol.Cell, 80, 2020
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7X5B
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![BU of 7x5b by Molmil](/molmil-images/mine/7x5b) | Crystal structure of RuvB | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Holliday junction ATP-dependent DNA helicase RuvB | Authors: | Lin, Z, Qu, Q, Zhang, X, Zhou, Z, Dai, L. | Deposit date: | 2022-03-04 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Cryo-EM structure of the RuvAB-Holliday junction intermediate complex from Pseudomonas aeruginosa. Front Plant Sci, 14, 2023
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7X5A
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![BU of 7x5a by Molmil](/molmil-images/mine/7x5a) | CryoEM structure of RuvA-Holliday junction complex | Descriptor: | DNA (26-MER), Holliday junction ATP-dependent DNA helicase RuvA | Authors: | Lin, Z, Qu, Q, Zhang, X, Zhou, Z. | Deposit date: | 2022-03-04 | Release date: | 2023-03-08 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Cryo-EM structure of the RuvAB-Holliday junction intermediate complex from Pseudomonas aeruginosa. Front Plant Sci, 14, 2023
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7X7Q
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![BU of 7x7q by Molmil](/molmil-images/mine/7x7q) | CryoEM structure of RuvA-RuvB-Holliday junction complex | Descriptor: | DNA (26-MER), DNA (40-MER), Holliday junction ATP-dependent DNA helicase RuvA, ... | Authors: | Lin, Z, Qu, Q, Zhang, X, Zhou, Z. | Deposit date: | 2022-03-10 | Release date: | 2023-03-15 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (7.02 Å) | Cite: | Cryo-EM structure of the RuvAB-Holliday junction intermediate complex from Pseudomonas aeruginosa. Front Plant Sci, 14, 2023
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7X7P
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![BU of 7x7p by Molmil](/molmil-images/mine/7x7p) | CryoEM structure of dsDNA-RuvB-RuvA domain3 complex | Descriptor: | DNA, Holliday junction ATP-dependent DNA helicase RuvA, Holliday junction ATP-dependent DNA helicase RuvB | Authors: | Lin, Z, Qu, Q, Zhang, X, Zhou, Z. | Deposit date: | 2022-03-10 | Release date: | 2023-03-15 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (7.02 Å) | Cite: | Cryo-EM structure of the RuvAB-Holliday junction intermediate complex from Pseudomonas aeruginosa. Front Plant Sci, 14, 2023
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7LCI
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![BU of 7lci by Molmil](/molmil-images/mine/7lci) | PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex | Descriptor: | 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Belousoff, M.J, Johnson, R.M, Drulyte, I, Yu, L, Kotecha, A, Danev, R, Wootten, D, Zhang, X, Sexton, P.M. | Deposit date: | 2021-01-11 | Release date: | 2021-01-20 | Last modified: | 2021-09-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Evolving cryo-EM structural approaches for GPCR drug discovery. Structure, 29, 2021
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