4RSQ

2.9A resolution structure of SRPN2 (K198C/E359C) from Anopheles gambiae

Summary for 4RSQ

Entry DOI	10.2210/pdb4rsq/pdb
Descriptor	Serpin 2 (1 entity in total)
Functional Keywords	serpin, serine protease, insect immunity, hydrolase inhibitor
Biological source	Anopheles gambiae (African malaria mosquito)
Total number of polymer chains	12
Total formula weight	543738.98
Authors	Lovell, S.,Battaile, K.P.,Zhang, X.,Meekins, D.A.,An, C.,Michel, K. (deposition date: 2014-11-10, release date: 2014-12-24, Last modification date: 2023-09-20)
Primary citation	Zhang, X.,Meekins, D.A.,An, C.,Zolkiewski, M.,Battaile, K.P.,Kanost, M.R.,Lovell, S.,Michel, K. Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae. J.Biol.Chem., 290:2946-2956, 2015 Cited by PubMed: 25525260 DOI: 10.1074/jbc.M114.625665 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation