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3UIA
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BU of 3uia by Molmil
Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Glycoprotein 41
Authors:Liu, J, Lu, M.
Deposit date:2011-11-04
Release date:2013-05-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
To be Published
2OMJ
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BU of 2omj by Molmil
solution structure of LARG PDZ domain
Descriptor: Rho guanine nucleotide exchange factor 12
Authors:Liu, J, Huang, H, Hu, Q.
Deposit date:2007-01-22
Release date:2008-01-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:solution structure and dynamics of the LARG PDZ domain
To be Published
2OS6
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BU of 2os6 by Molmil
Solution structure of LARG PDZ domain in complex with C-terminal octa-peptide of Plexin B1
Descriptor: C-terminal peptide of Plexin-B1, Rho guanine nucleotide exchange factor 12
Authors:Liu, J, Huang, H, Yang, Y.
Deposit date:2007-02-05
Release date:2008-02-12
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the LARG PDZ domain in complex with C-terminal peptide of Plexin B1
To be Published
4HLR
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BU of 4hlr by Molmil
Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
Descriptor: Gp41, HEXANE-1,6-DIOL
Authors:Liu, J, Lu, M.
Deposit date:2012-10-17
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
To be Published
8IB0
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BU of 8ib0 by Molmil
The amyloid structure of mouse RIPK1 RHIM-containing domain by solid-state NMR
Descriptor: Receptor-interacting serine/threonine-protein kinase 1
Authors:Liu, J, Xialian, W.
Deposit date:2023-02-09
Release date:2023-03-22
Last modified:2024-08-28
Method:SOLID-STATE NMR
Cite:The structure of mouse RIPK1 RHIM-containing domain as a homo-amyloid and in RIPK1/RIPK3 complex.
Nat Commun, 15, 2024
4QLW
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BU of 4qlw by Molmil
Azurin mutant M121E with iron
Descriptor: Azurin, FE (III) ION, NITRATE ION, ...
Authors:Liu, J, Robinson, H, Lu, Y.
Deposit date:2014-06-13
Release date:2014-08-13
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Redesigning the Blue Copper Azurin into a Redox-Active Mononuclear Nonheme Iron Protein: Preparation and Study of Fe(II)-M121E Azurin.
J.Am.Chem.Soc., 136, 2014
4QKT
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BU of 4qkt by Molmil
Azurin mutant M121EM44K with copper
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Azurin, ...
Authors:Liu, J, Robinson, H, Lu, Y.
Deposit date:2014-06-09
Release date:2014-08-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:Redesigning the Blue Copper Azurin into a Redox-Active Mononuclear Nonheme Iron Protein: Preparation and Study of Fe(II)-M121E Azurin.
J.Am.Chem.Soc., 136, 2014
8XHR
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BU of 8xhr by Molmil
Crystal structure of Mycobacterium tuberculosis MenT3 bound with CTP
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Nucleotidyl transferase AbiEii/AbiGii toxin family protein
Authors:Liu, J, Yashiro, Y, Tomita, K.
Deposit date:2023-12-18
Release date:2024-02-28
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3.
Nucleic Acids Res., 52, 2024
7D60
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BU of 7d60 by Molmil
Cryo-EM Structure of human CALHM5 in the presence of rubidium red
Descriptor: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
Authors:Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
Deposit date:2020-09-28
Release date:2020-12-23
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
7D65
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BU of 7d65 by Molmil
Cryo-EM Structure of human CALHM5 in the presence of Ca2+
Descriptor: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
Authors:Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
Deposit date:2020-09-29
Release date:2020-12-23
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
7D61
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BU of 7d61 by Molmil
Cryo-EM Structure of human CALHM5 in the presence of EDTA
Descriptor: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
Authors:Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
Deposit date:2020-09-28
Release date:2020-12-23
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
8GK3
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BU of 8gk3 by Molmil
Cytochrome P450 3A7 in complex with Dehydroepiandrosterone sulfate
Descriptor: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, Cytochrome P450 3A7, PROTOPORPHYRIN IX CONTAINING FE
Authors:Liu, J, Scott, E.E.
Deposit date:2023-03-16
Release date:2023-07-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate.
J.Biol.Chem., 299, 2023
5X0W
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BU of 5x0w by Molmil
Molecular mechanism for the binding between Sharpin and HOIP
Descriptor: E3 ubiquitin-protein ligase RNF31, Sharpin
Authors:Liu, J, Li, F, Cheng, X, Pan, L.
Deposit date:2017-01-23
Release date:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly
Cell Rep, 21, 2017
7CJB
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BU of 7cjb by Molmil
VHL recognizes hydroxyproline in RIPK1
Descriptor: Elongin-B, Elongin-C, GLYCEROL, ...
Authors:Liu, J, Wang, Y, Pan, L.
Deposit date:2020-07-09
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:VHL recognizes hydroxyproline in RIPK1
To Be Published
7V8E
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BU of 7v8e by Molmil
Crystal structure of IpaH1.4 LRR domain bound to HOIL-1L UBL domain.
Descriptor: RING-type E3 ubiquitin transferase, RanBP-type and C3HC4-type zinc finger-containing protein 1
Authors:Liu, J, Wang, Y, Pan, L.
Deposit date:2021-08-22
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8G
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BU of 7v8g by Molmil
Crystal structure of HOIP RING1 domain bound to IpaH1.4 LRR domain
Descriptor: E3 ubiquitin-protein ligase RNF31, RING-type E3 ubiquitin transferase, ZINC ION
Authors:Liu, J, Wang, Y, Pan, L.
Deposit date:2021-08-23
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8F
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BU of 7v8f by Molmil
Crystal structure of UBE2L3 bound to HOIP RING1 domain.
Descriptor: E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION
Authors:Liu, J, Wang, Y, Pan, L.
Deposit date:2021-08-22
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8H
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BU of 7v8h by Molmil
Crystal structure of LRR domain from Shigella flexneri IpaH1.4
Descriptor: RING-type E3 ubiquitin transferase
Authors:Liu, J, Wang, Y, Pan, L.
Deposit date:2021-08-23
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
3ZP0
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BU of 3zp0 by Molmil
INFLUENZA VIRUS (VN1194) H5 HA with LSTa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose
Authors:Liu, J, Stevens, D.J, Gamblin, S.J, Skehel, J.J.
Deposit date:2013-02-26
Release date:2013-10-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Changes in the Hemagglutinin of H5N1 Viruses During Human Infection - Influence on Receptor Binding.
Virology, 447, 2013
3ZPA
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BU of 3zpa by Molmil
INFLUENZA VIRUS (VN1194) H5 I155F mutant HA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ
Authors:Liu, J, Chen, Z, Stevens, D.J, Gamblin, S.J, Skehel, J.J.
Deposit date:2013-02-27
Release date:2013-10-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Changes in the Hemagglutinin of H5N1 Viruses During Human Infection - Influence on Receptor Binding.
Virology, 447, 2013
7LKY
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BU of 7lky by Molmil
Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641
Descriptor: DIMETHYL SULFOXIDE, Isoform 1 of PHD finger protein 1, Peptidomimetic inhibitor UNC6641, ...
Authors:Liu, J, Kutateladze, T.G.
Deposit date:2021-02-03
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1).
J.Med.Chem., 64, 2021
8J5D
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BU of 8j5d by Molmil
Cryo-EM structure of starch degradation complex of BAM1-LSF1-MDH
Descriptor: Beta-amylase 1, chloroplastic, Malate dehydrogenase, ...
Authors:Guan, Z.Y, Liu, J, Yan, J.J.
Deposit date:2023-04-21
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The LIKE SEX FOUR 1-malate dehydrogenase complex functions as a scaffold to recruit beta-amylase to promote starch degradation.
Plant Cell, 36, 2023
6V9C
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BU of 6v9c by Molmil
Crystal structure of FGFR4 kinase domain in complex with covalent inhibitor
Descriptor: Fibroblast growth factor receptor 4, N-[(3R,4S)-4-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}oxolan-3-yl]prop-2-enamide, SULFATE ION
Authors:Liu, J, Liu, H.
Deposit date:2019-12-13
Release date:2020-03-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma.
Acs Med.Chem.Lett., 11, 2020
6WXJ
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BU of 6wxj by Molmil
CSF1R signaling is a regulator of pathogenesis in progressive MS
Descriptor: 4-(3-{[(2S)-2-(6-methoxypyridin-3-yl)-2,3-dihydro-1,4-benzodioxin-6-yl]methyl}-3H-imidazo[4,5-b]pyridin-6-yl)-2-methylbut-3-yn-2-amine, Macrophage colony-stimulating factor 1 receptor
Authors:Liu, J.
Deposit date:2020-05-10
Release date:2021-02-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:CSF1R signaling is a regulator of pathogenesis in progressive MS.
Cell Death Dis, 11, 2020
6XDM
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BU of 6xdm by Molmil
STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH AN ARYL KETONE INHIBITOR
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Histone deacetylase 2, ...
Authors:Klein, D.J, Liu, J.
Deposit date:2020-06-11
Release date:2020-07-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance.
Acs Med.Chem.Lett., 11, 2020

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