6JM5
| Crystal structure of TBC1D23 C terminal domain | Descriptor: | SODIUM ION, TBC1 domain family member 23 | Authors: | Sun, Q, Huang, W. | Deposit date: | 2019-03-07 | Release date: | 2019-10-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCH. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6A3B
| MVM NES mutant Nm13 in complex with CRM1-Ran-RanBP1 | Descriptor: | 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2018-06-15 | Release date: | 2019-06-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
|
|
6CRQ
| Glutaraldehyde-treated BG505 SOSIP.664 Env in complex with PGV04 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Pallesen, J, Ward, A.B. | Deposit date: | 2018-03-19 | Release date: | 2018-04-18 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins. PLoS Pathog., 14, 2018
|
|
7KEW
| Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-43 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BDBV-43 Fab heavy chain, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2020-10-13 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
|
|
7KFG
| Antibody Fab BDBV-289 | Descriptor: | Antibody Fab BDBV-289 heavy chain, Antibody Fab BDBV-289 light chain, DI(HYDROXYETHYL)ETHER | Authors: | Murin, C.D, Bruhn, J.F, Ward, A.B. | Deposit date: | 2020-10-13 | Release date: | 2021-04-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
|
|
7KEX
| |
7KFE
| Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-329 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody BDBV-329 heavy chain, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2020-10-13 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
|
|
7KF9
| |
7KFH
| Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-437 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab EBOV-437 heavy chain, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2020-10-13 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
|
|
7KFB
| Ebola virus GP (mucin deleted, Makona strain) bound to antibody Fab EBOV-442 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab EBOV-442 heavy chain, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2020-10-13 | Release date: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
|
|
7KEJ
| BDBV-289 bound to EBOV GPdMuc Makona | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain (HC) BDBV-289, Antibody Fab light chain (LC) BDBV-289, ... | Authors: | Murin, C.D, Ward, A.B. | Deposit date: | 2020-10-11 | Release date: | 2021-06-23 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Rep, 35, 2021
|
|
7LVB
| CHOLERA TOXIN B SUBUNIT WITH ATTACHED SIV EPITOPE | Descriptor: | CHLORIDE ION, Cholera enterotoxin B-subunit,Surface protein gp120, TRIETHYLENE GLYCOL, ... | Authors: | Patskovsky, Y, Cardozo, T.J. | Deposit date: | 2021-02-24 | Release date: | 2022-03-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Cholera toxin B scaffolded, focused SIV V2 epitope elicits antibodies that influence the risk of SIV mac251 acquisition in macaques. Front Immunol, 14, 2023
|
|
8HQ3
| KL1 in complex with CRM1-Ran-RanBP1 | Descriptor: | CHLORIDE ION, CRM1 isoform 1, DIMETHYL SULFOXIDE, ... | Authors: | Sun, Q, Jian, L. | Deposit date: | 2022-12-13 | Release date: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of Aminoratjadone Derivatives as Potent Noncovalent CRM1 Inhibitors. J.Med.Chem., 66, 2023
|
|
8HQ6
| KL2 in complex with CRM1-Ran-RanBP1 | Descriptor: | CHLORIDE ION, CRM1 isoform 1, DIMETHYL SULFOXIDE, ... | Authors: | Sun, Q, Jian, L. | Deposit date: | 2022-12-13 | Release date: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Discovery of Aminoratjadone Derivatives as Potent Noncovalent CRM1 Inhibitors. J.Med.Chem., 66, 2023
|
|
7XUX
| |
6A3A
| MVM NES mutant Nm2 in complex with CRM1-Ran-RanBP1 | Descriptor: | 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2018-06-15 | Release date: | 2019-06-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
|
|
6A3E
| MVM NES mutant Nm15 in complex with CRM1-Ran-RanBP1 | Descriptor: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2018-06-15 | Release date: | 2019-06-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
|
|
6A3C
| MVM NES mutant Nm12 in complex with CRM1-Ran-RanBP1 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2018-06-15 | Release date: | 2019-06-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
|
|
6A38
| MVM NS2 NES in complex with CRM1-Ran-RanBP1 | Descriptor: | 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2018-06-15 | Release date: | 2019-06-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
|
|
2GHU
| Crystal structure of falcipain-2 from Plasmodium falciparum | Descriptor: | falcipain 2 | Authors: | Hogg, T, Nagarajan, K, Schmidt, C.L, Hilgenfeld, R. | Deposit date: | 2006-03-27 | Release date: | 2006-06-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural and Functional Characterization of Falcipain-2, a Hemoglobinase from the Malarial Parasite Plasmodium falciparum. J.Biol.Chem., 281, 2006
|
|
7DKL
| |
6KFT
| MVM NS2 mutant Nm42 in complex with CRM1-Ran-RanBP1 | Descriptor: | 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... | Authors: | Sun, Q, Li, Y. | Deposit date: | 2019-07-08 | Release date: | 2020-07-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021
|
|
6MNR
| Rhesus macaque anti-HIV V3 antibody DH753 with gp120 V3 ZAM18 peptide | Descriptor: | 1,2-ETHANEDIOL, Ab DH753 heavy chain Fab fragment, Ab DH753 light chain, ... | Authors: | Nicely, N.I. | Deposit date: | 2018-10-02 | Release date: | 2019-07-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations. Nat Commun, 10, 2019
|
|
6MNQ
| Rhesus macaque anti-HIV V3 antibody DH727.2 with gp120 V3 ZAM18 peptide | Descriptor: | 1,2-ETHANEDIOL, Ab DH727.2 heavy chain Fab fragment, Ab DH727.2 light chain, ... | Authors: | Nicely, N.I. | Deposit date: | 2018-10-02 | Release date: | 2019-07-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.804 Å) | Cite: | Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations. Nat Commun, 10, 2019
|
|
6MNS
| Rhesus macaque anti-HIV V3 antibody DH753 with gp120 V3 ZAM18 peptide | Descriptor: | Ab DH753 heavy chain Fab fragment, Ab DH753 light chain, Envelope glylcoprotein, ... | Authors: | Nicely, N.I. | Deposit date: | 2018-10-02 | Release date: | 2019-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations. Nat Commun, 10, 2019
|
|